RU2006141653A - Доставка противогрибковых лекарственных средств - Google Patents
Доставка противогрибковых лекарственных средств Download PDFInfo
- Publication number
- RU2006141653A RU2006141653A RU2006141653/15A RU2006141653A RU2006141653A RU 2006141653 A RU2006141653 A RU 2006141653A RU 2006141653/15 A RU2006141653/15 A RU 2006141653/15A RU 2006141653 A RU2006141653 A RU 2006141653A RU 2006141653 A RU2006141653 A RU 2006141653A
- Authority
- RU
- Russia
- Prior art keywords
- antifungal
- concentration
- antifungal composition
- compound
- composition according
- Prior art date
Links
- 230000001716 anti-fugal effect Effects 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000012871 anti-fungal composition Substances 0.000 claims 24
- VVJKKWFAADXIJK-UHFFFAOYSA-N Allylamine Chemical compound NCC=C VVJKKWFAADXIJK-UHFFFAOYSA-N 0.000 claims 18
- 230000000843 anti-fungal effect Effects 0.000 claims 18
- 229940121375 antifungal agent Drugs 0.000 claims 18
- 150000001875 compounds Chemical class 0.000 claims 18
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical group C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 claims 7
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 claims 7
- 206010017533 Fungal infection Diseases 0.000 claims 7
- 208000031888 Mycoses Diseases 0.000 claims 7
- 210000000282 nail Anatomy 0.000 claims 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 5
- IIUZTXTZRGLYTI-UHFFFAOYSA-N Dihydrogriseofulvin Natural products COC1CC(=O)CC(C)C11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 IIUZTXTZRGLYTI-UHFFFAOYSA-N 0.000 claims 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 4
- UXWOXTQWVMFRSE-UHFFFAOYSA-N Griseoviridin Natural products O=C1OC(C)CC=C(C(NCC=CC=CC(O)CC(O)C2)=O)SCC1NC(=O)C1=COC2=N1 UXWOXTQWVMFRSE-UHFFFAOYSA-N 0.000 claims 4
- DDUHZTYCFQRHIY-UHFFFAOYSA-N Negwer: 6874 Natural products COC1=CC(=O)CC(C)C11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 DDUHZTYCFQRHIY-UHFFFAOYSA-N 0.000 claims 4
- 229960002867 griseofulvin Drugs 0.000 claims 4
- DDUHZTYCFQRHIY-RBHXEPJQSA-N griseofulvin Chemical compound COC1=CC(=O)C[C@@H](C)[C@@]11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 DDUHZTYCFQRHIY-RBHXEPJQSA-N 0.000 claims 4
- 239000011877 solvent mixture Substances 0.000 claims 4
- 230000000699 topical effect Effects 0.000 claims 4
- XMAYWYJOQHXEEK-OZXSUGGESA-N (2R,4S)-ketoconazole Chemical compound C1CN(C(=O)C)CCN1C(C=C1)=CC=C1OC[C@@H]1O[C@@](CN2C=NC=C2)(C=2C(=CC(Cl)=CC=2)Cl)OC1 XMAYWYJOQHXEEK-OZXSUGGESA-N 0.000 claims 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 3
- BYBLEWFAAKGYCD-UHFFFAOYSA-N Miconazole Chemical compound ClC1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 BYBLEWFAAKGYCD-UHFFFAOYSA-N 0.000 claims 3
- 229960004125 ketoconazole Drugs 0.000 claims 3
- 229960002509 miconazole Drugs 0.000 claims 3
- DOMXUEMWDBAQBQ-WEVVVXLNSA-N terbinafine Chemical compound C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 DOMXUEMWDBAQBQ-WEVVVXLNSA-N 0.000 claims 3
- WRMNZCZEMHIOCP-UHFFFAOYSA-N 2-phenylethanol Chemical compound OCCC1=CC=CC=C1 WRMNZCZEMHIOCP-UHFFFAOYSA-N 0.000 claims 2
- 241000223229 Trichophyton rubrum Species 0.000 claims 2
- 235000019445 benzyl alcohol Nutrition 0.000 claims 2
- 235000019441 ethanol Nutrition 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 229960002722 terbinafine Drugs 0.000 claims 2
- BLSQLHNBWJLIBQ-OZXSUGGESA-N (2R,4S)-terconazole Chemical compound C1CN(C(C)C)CCN1C(C=C1)=CC=C1OC[C@@H]1O[C@@](CN2N=CN=C2)(C=2C(=CC(Cl)=CC=2)Cl)OC1 BLSQLHNBWJLIBQ-OZXSUGGESA-N 0.000 claims 1
- LEZWWPYKPKIXLL-UHFFFAOYSA-N 1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole Chemical compound C1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 LEZWWPYKPKIXLL-UHFFFAOYSA-N 0.000 claims 1
- VHVPQPYKVGDNFY-DFMJLFEVSA-N 2-[(2r)-butan-2-yl]-4-[4-[4-[4-[[(2r,4s)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one Chemical compound O=C1N([C@H](C)CC)N=CN1C1=CC=C(N2CCN(CC2)C=2C=CC(OC[C@@H]3O[C@](CN4N=CN=C4)(OC3)C=3C(=CC(Cl)=CC=3)Cl)=CC=2)C=C1 VHVPQPYKVGDNFY-DFMJLFEVSA-N 0.000 claims 1
- 241001480036 Epidermophyton floccosum Species 0.000 claims 1
- 241000233866 Fungi Species 0.000 claims 1
- 241000893980 Microsporum canis Species 0.000 claims 1
- 208000002474 Tinea Diseases 0.000 claims 1
- 241001459572 Trichophyton interdigitale Species 0.000 claims 1
- 241001045770 Trichophyton mentagrophytes Species 0.000 claims 1
- 229960005074 butoconazole Drugs 0.000 claims 1
- SWLMUYACZKCSHZ-UHFFFAOYSA-N butoconazole Chemical compound C1=CC(Cl)=CC=C1CCC(SC=1C(=CC=CC=1Cl)Cl)CN1C=NC=C1 SWLMUYACZKCSHZ-UHFFFAOYSA-N 0.000 claims 1
- 229960004022 clotrimazole Drugs 0.000 claims 1
- VNFPBHJOKIVQEB-UHFFFAOYSA-N clotrimazole Chemical compound ClC1=CC=CC=C1C(N1C=NC=C1)(C=1C=CC=CC=1)C1=CC=CC=C1 VNFPBHJOKIVQEB-UHFFFAOYSA-N 0.000 claims 1
- 229960003913 econazole Drugs 0.000 claims 1
- 210000000981 epithelium Anatomy 0.000 claims 1
- 210000004904 fingernail bed Anatomy 0.000 claims 1
- 229960004884 fluconazole Drugs 0.000 claims 1
- RFHAOTPXVQNOHP-UHFFFAOYSA-N fluconazole Chemical compound C1=NC=NN1CC(C=1C(=CC(F)=CC=1)F)(O)CN1C=NC=N1 RFHAOTPXVQNOHP-UHFFFAOYSA-N 0.000 claims 1
- 229960004130 itraconazole Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229940126601 medicinal product Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229960003483 oxiconazole Drugs 0.000 claims 1
- QRJJEGAJXVEBNE-MOHJPFBDSA-N oxiconazole Chemical compound ClC1=CC(Cl)=CC=C1CO\N=C(C=1C(=CC(Cl)=CC=1)Cl)\CN1C=NC=C1 QRJJEGAJXVEBNE-MOHJPFBDSA-N 0.000 claims 1
- 229940067107 phenylethyl alcohol Drugs 0.000 claims 1
- 229960000580 terconazole Drugs 0.000 claims 1
- -1 thioconazole Chemical compound 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/832,933 | 2004-04-27 | ||
| US10/832,933 US20050238672A1 (en) | 2004-04-27 | 2004-04-27 | Antifungal drug delivery |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2006141653A true RU2006141653A (ru) | 2008-06-10 |
Family
ID=35136720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2006141653/15A RU2006141653A (ru) | 2004-04-27 | 2005-04-25 | Доставка противогрибковых лекарственных средств |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20050238672A1 (https=) |
| EP (1) | EP1755575A4 (https=) |
| JP (1) | JP2007534764A (https=) |
| KR (1) | KR20070024543A (https=) |
| CN (1) | CN101022779B (https=) |
| AU (1) | AU2005237541A1 (https=) |
| BR (1) | BRPI0510286A (https=) |
| CA (1) | CA2564134A1 (https=) |
| IL (1) | IL178750A0 (https=) |
| MX (1) | MXPA06012426A (https=) |
| NO (1) | NO20065422L (https=) |
| RU (1) | RU2006141653A (https=) |
| WO (1) | WO2005105072A2 (https=) |
| ZA (1) | ZA200609821B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2699653C1 (ru) * | 2019-03-22 | 2019-09-09 | федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) (ФГАОУ ВО Первый МГМУ им. И.М. Сеченова Минздрава России (Се | Средство для лечения микоза ногтей |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0506139D0 (en) * | 2005-03-24 | 2005-05-04 | Transphase Ltd | A transdermal topical composition and its uses |
| MXPA05012961A (es) * | 2005-11-30 | 2007-05-30 | Fernando Ahumada Ayala | Preparaciones para el cuidado de las unas que contienen clorhidrato de terbinafina. |
| WO2007098591A2 (en) * | 2006-03-02 | 2007-09-07 | Nuvo Research Inc. | Topical nail formulation |
| CN101677953A (zh) * | 2007-02-21 | 2010-03-24 | 纸型电池有限公司 | 用于离子电渗疗法的特比萘芬制剂 |
| GB201011212D0 (en) * | 2010-07-02 | 2010-08-18 | Linde Aktiengesellshcaft | Gas storage apparatus |
| KR20120056314A (ko) * | 2010-11-24 | 2012-06-04 | 주식회사유한양행 | 테르비나핀 또는 그의 염을 함유하는 국소 항진균 조성물 |
| WO2014059008A1 (en) | 2012-10-09 | 2014-04-17 | The Procter & Gamble Company | Method of identifying or evaluating beneficial actives and compositions containing the same |
| WO2014059009A1 (en) | 2012-10-09 | 2014-04-17 | The Procter & Gamble Company | Method of identifying synergistic cosmetic combinations |
| US8697753B1 (en) | 2013-02-07 | 2014-04-15 | Polichem Sa | Method of treating onychomycosis |
| US9138393B2 (en) | 2013-02-08 | 2015-09-22 | The Procter & Gamble Company | Cosmetic compositions containing substituted azole and methods for improving the appearance of aging skin |
| US9144538B2 (en) | 2013-02-08 | 2015-09-29 | The Procter & Gamble Company | Cosmetic compositions containing substituted azole and methods for alleviating the signs of photoaged skin |
| GB201317005D0 (en) * | 2013-09-25 | 2013-11-06 | Blueberry Therapeutics Ltd | Composition and methods of treatment |
| EP2952208A1 (en) * | 2014-06-04 | 2015-12-09 | Universidade de Santiago de Compostela | Hydroalcoholic system for nail treatment |
| US11554108B2 (en) | 2016-08-29 | 2023-01-17 | Xeropedix, Inc. | Methods and compositions for treating cutaneous fungal infections |
| EP3503874A1 (en) * | 2016-08-29 | 2019-07-03 | Carl F. Schanbacher | Methods and compositions for treating cutaneous fungal infections |
| EP4041839A4 (en) * | 2019-10-08 | 2023-10-11 | Hallux, Inc. | ONYCHOMYCOSIS TREATMENT COMPOSITIONS AND METHODS |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3382151A (en) * | 1964-01-13 | 1968-05-07 | Mavala Sa | Composition for strengthening nails |
| DE3544983A1 (de) * | 1985-12-19 | 1987-06-25 | Hoechst Ag | Antimykotisch wirksamer nagellack |
| US4820724A (en) * | 1986-03-31 | 1989-04-11 | University Of Southern California | Dual phase solvent carrier system |
| US4894375A (en) * | 1986-09-29 | 1990-01-16 | Merck & Co., Inc. | Method of controlling mycotic infections and compositions therefor |
| FR2673537B1 (fr) * | 1991-03-08 | 1993-06-11 | Oreal | Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes. |
| US5487776A (en) * | 1994-03-17 | 1996-01-30 | Nimni; Marcel | Anti-fungal nail lacquer and method therefor |
| US5696164A (en) * | 1994-12-22 | 1997-12-09 | Johnson & Johnson Consumer Products, Inc. | Antifungal treatment of nails |
| US5652256A (en) * | 1995-06-06 | 1997-07-29 | Knowles; W. Roy | Topical composition for fungal treatment |
| US5814308A (en) * | 1996-03-26 | 1998-09-29 | Zhang; Ke | Methods for the treatment of gastrointestinal tract disorders |
| US6030948A (en) * | 1997-12-19 | 2000-02-29 | Mann; Morris A. | Hair regeneration compositions for treatment of alopecia and methods of application related thereto |
| DK0983037T3 (da) * | 1998-02-09 | 2003-09-01 | Macrochem Corp | Fungicid neglelak |
| US6143794A (en) * | 1998-04-17 | 2000-11-07 | Bertek Pharmaceuticals, Inc. | Topical formulations for the treatment of nail fungal diseases |
| US6495124B1 (en) * | 2000-02-14 | 2002-12-17 | Macrochem Corporation | Antifungal nail lacquer and method using same |
| US6281239B1 (en) * | 2000-04-12 | 2001-08-28 | Bradley Pharmeaceuticals, Inc. | Method of treating onychomycosis |
| US6585963B1 (en) * | 2001-02-15 | 2003-07-01 | Watson Pharmaceuticals, Inc. | Nail compositions and methods of administering same |
| GB0108082D0 (en) * | 2001-03-30 | 2001-05-23 | Novartis Consumer Health Sa | Topical composition |
| US6765001B2 (en) * | 2001-12-21 | 2004-07-20 | Medicis Pharmaceutical Corporation | Compositions and methods for enhancing corticosteroid delivery |
| EP2106805B1 (en) * | 2003-03-21 | 2011-06-15 | Nexmed Holdings, Inc. | Antifungal nail coat and method of use |
| US20040191207A1 (en) * | 2003-03-31 | 2004-09-30 | Lipari John M. | Alpha-hydroxy acid ester drug delivery compositions and methods of use |
| HUP0303313A2 (hu) * | 2003-10-09 | 2005-07-28 | Richter Gedeon Vegyészeti Gyár Rt. | Transzdermális gyógyszerkészítmények |
-
2004
- 2004-04-27 US US10/832,933 patent/US20050238672A1/en not_active Abandoned
-
2005
- 2005-04-25 RU RU2006141653/15A patent/RU2006141653A/ru not_active Application Discontinuation
- 2005-04-25 CA CA002564134A patent/CA2564134A1/en not_active Abandoned
- 2005-04-25 CN CN2005800133411A patent/CN101022779B/zh not_active Expired - Fee Related
- 2005-04-25 KR KR1020067024858A patent/KR20070024543A/ko not_active Withdrawn
- 2005-04-25 EP EP05739804A patent/EP1755575A4/en not_active Withdrawn
- 2005-04-25 AU AU2005237541A patent/AU2005237541A1/en not_active Abandoned
- 2005-04-25 BR BRPI0510286-3A patent/BRPI0510286A/pt not_active IP Right Cessation
- 2005-04-25 ZA ZA200609821A patent/ZA200609821B/xx unknown
- 2005-04-25 WO PCT/US2005/014246 patent/WO2005105072A2/en not_active Ceased
- 2005-04-25 MX MXPA06012426A patent/MXPA06012426A/es not_active Application Discontinuation
- 2005-04-25 JP JP2007510881A patent/JP2007534764A/ja active Pending
-
2006
- 2006-10-19 IL IL178750A patent/IL178750A0/en unknown
- 2006-11-24 NO NO20065422A patent/NO20065422L/no not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2699653C1 (ru) * | 2019-03-22 | 2019-09-09 | федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) (ФГАОУ ВО Первый МГМУ им. И.М. Сеченова Минздрава России (Се | Средство для лечения микоза ногтей |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2007534764A (ja) | 2007-11-29 |
| AU2005237541A1 (en) | 2005-11-10 |
| IL178750A0 (en) | 2007-05-15 |
| WO2005105072A3 (en) | 2006-03-02 |
| CA2564134A1 (en) | 2005-11-10 |
| EP1755575A2 (en) | 2007-02-28 |
| BRPI0510286A (pt) | 2007-10-30 |
| US20050238672A1 (en) | 2005-10-27 |
| CN101022779A (zh) | 2007-08-22 |
| NO20065422L (no) | 2007-01-19 |
| MXPA06012426A (es) | 2007-03-28 |
| CN101022779B (zh) | 2010-12-08 |
| KR20070024543A (ko) | 2007-03-02 |
| ZA200609821B (en) | 2008-06-25 |
| WO2005105072A2 (en) | 2005-11-10 |
| EP1755575A4 (en) | 2010-09-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2006141653A (ru) | Доставка противогрибковых лекарственных средств | |
| DK2512479T3 (en) | Compositions for the treatment of peripheral vascular disease | |
| CA2645070C (en) | Pharmaceutical composition for external use | |
| JP2007534764A5 (https=) | ||
| RU2419429C2 (ru) | Фармацевтическая композиция для наружного применения | |
| ZA200403035B (en) | Imidazole-4-carboxamide derivatives, preparation and use thereof for treatment of obesity. | |
| JP2017536382A5 (https=) | ||
| EP3315492A1 (en) | Pyrazole derivative, or pharmaceutically acceptable salt thereof | |
| CN112105601A (zh) | 作为细胞死亡抑制剂用于治疗例如卒中的3-(苄基氨基)-4-(环己基氨基)-n-(2-哌嗪-1-基)乙基)苯磺酰胺衍生物和相关的ferrostatin-1类似物 | |
| Carmignani et al. | Novel hypotensive agents from Verbesina c aracasana. 8. Synthesis and pharmacology of (3, 4-Dimethoxycinnamoyl)-N-agmatine and Synthetic Analogues1 | |
| RU2006128445A (ru) | Ацетилиновые пиперазиновые соединения и их применение в качестве антагонистов метаботропных глутаматных рецепторов | |
| WO2015106283A1 (en) | Antifungal compounds | |
| US10537549B2 (en) | Dihydroisoxazole compound for use in controlling sea lice | |
| ZA200505037B (en) | Pyridinalkyl-Aminoalkyl-1H-indole Derivatives having an Inhibitory Action on 5-HT and Serotonin Reuptake as Antidepressants and Anxiolytics | |
| NO20050279D0 (no) | Ny fremgangsmate | |
| WO2010132852A2 (en) | Protease inhibitors | |
| KR101733189B1 (ko) | 손톱 또는 발톱 성장 촉진용 조성물 | |
| CN115667215A (zh) | 抗冠状病毒的广谱抗病毒药物 | |
| KR101525019B1 (ko) | Ｎｒｆ2 활성화능을 갖는 신규 화합물, 이를 포함하는 약학적 조성물 | |
| US20080249088A1 (en) | Topical Delivery of Antifungal Drugs | |
| JPWO2021092239A5 (https=) | ||
| JP2008531526A (ja) | 腎臓病の予防または治療に有用な薬物を調製するためのピラゾール誘導体の使用 | |
| EP2168951A1 (en) | Azolylmethylenehydrazine derivative and use thereof | |
| Ghannoum et al. | Amorolfine | |
| EP2377855A1 (en) | A valsartanamide dinitrate derivative for the treatment of vascular and metabolic diseases |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA93 | Acknowledgement of application withdrawn (no request for examination) |
Effective date: 20080707 |
|
| FZ9A | Application not withdrawn (correction of the notice of withdrawal) |
Effective date: 20080716 |
|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20090811 |