BRPI0510286A - composiçaõ antifúngica para aplicação tópica na pele ou nas unhas, e, uso de um composto antfúngico de alil-amina - Google Patents
composiçaõ antifúngica para aplicação tópica na pele ou nas unhas, e, uso de um composto antfúngico de alil-aminaInfo
- Publication number
- BRPI0510286A BRPI0510286A BRPI0510286-3A BRPI0510286A BRPI0510286A BR PI0510286 A BRPI0510286 A BR PI0510286A BR PI0510286 A BRPI0510286 A BR PI0510286A BR PI0510286 A BRPI0510286 A BR PI0510286A
- Authority
- BR
- Brazil
- Prior art keywords
- skin
- alcohol
- composition
- nails
- antifungal
- Prior art date
Links
- VVJKKWFAADXIJK-UHFFFAOYSA-N Allylamine Chemical compound NCC=C VVJKKWFAADXIJK-UHFFFAOYSA-N 0.000 title abstract 10
- 230000000843 anti-fungal effect Effects 0.000 title abstract 7
- 150000001875 compounds Chemical class 0.000 title abstract 7
- 229940121375 antifungal agent Drugs 0.000 title abstract 6
- 239000012871 anti-fungal composition Substances 0.000 title abstract 4
- 230000000699 topical effect Effects 0.000 title abstract 2
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical group C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 abstract 4
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 abstract 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 3
- WRMNZCZEMHIOCP-UHFFFAOYSA-N 2-phenylethanol Chemical compound OCCC1=CC=CC=C1 WRMNZCZEMHIOCP-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 206010017533 Fungal infection Diseases 0.000 abstract 1
- 206010017543 Fungal skin infection Diseases 0.000 abstract 1
- 208000031888 Mycoses Diseases 0.000 abstract 1
- 206010061304 Nail infection Diseases 0.000 abstract 1
- 235000019445 benzyl alcohol Nutrition 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- DOMXUEMWDBAQBQ-WEVVVXLNSA-N terbinafine Chemical compound C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 DOMXUEMWDBAQBQ-WEVVVXLNSA-N 0.000 abstract 1
- 229960002722 terbinafine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/832,933 US20050238672A1 (en) | 2004-04-27 | 2004-04-27 | Antifungal drug delivery |
| PCT/US2005/014246 WO2005105072A2 (en) | 2004-04-27 | 2005-04-25 | Antifungal drug delivery |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0510286A true BRPI0510286A (pt) | 2007-10-30 |
Family
ID=35136720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0510286-3A BRPI0510286A (pt) | 2004-04-27 | 2005-04-25 | composiçaõ antifúngica para aplicação tópica na pele ou nas unhas, e, uso de um composto antfúngico de alil-amina |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20050238672A1 (https=) |
| EP (1) | EP1755575A4 (https=) |
| JP (1) | JP2007534764A (https=) |
| KR (1) | KR20070024543A (https=) |
| CN (1) | CN101022779B (https=) |
| AU (1) | AU2005237541A1 (https=) |
| BR (1) | BRPI0510286A (https=) |
| CA (1) | CA2564134A1 (https=) |
| IL (1) | IL178750A0 (https=) |
| MX (1) | MXPA06012426A (https=) |
| NO (1) | NO20065422L (https=) |
| RU (1) | RU2006141653A (https=) |
| WO (1) | WO2005105072A2 (https=) |
| ZA (1) | ZA200609821B (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0506139D0 (en) * | 2005-03-24 | 2005-05-04 | Transphase Ltd | A transdermal topical composition and its uses |
| MXPA05012961A (es) * | 2005-11-30 | 2007-05-30 | Fernando Ahumada Ayala | Preparaciones para el cuidado de las unas que contienen clorhidrato de terbinafina. |
| WO2007098591A2 (en) * | 2006-03-02 | 2007-09-07 | Nuvo Research Inc. | Topical nail formulation |
| US20100168233A1 (en) * | 2007-02-21 | 2010-07-01 | Power Paper Ltd | Terbinafine formulation |
| GB201011212D0 (en) * | 2010-07-02 | 2010-08-18 | Linde Aktiengesellshcaft | Gas storage apparatus |
| KR20120056314A (ko) * | 2010-11-24 | 2012-06-04 | 주식회사유한양행 | 테르비나핀 또는 그의 염을 함유하는 국소 항진균 조성물 |
| US10302630B2 (en) | 2012-10-09 | 2019-05-28 | The Procter & Gamble Company | Method of identifying or evaluating beneficial actives and compositions containing the same |
| JP6189962B2 (ja) | 2012-10-09 | 2017-08-30 | ザ プロクター アンド ギャンブル カンパニー | 相乗作用する美容成分の組み合わせを特定する方法 |
| US8697753B1 (en) | 2013-02-07 | 2014-04-15 | Polichem Sa | Method of treating onychomycosis |
| US9144538B2 (en) | 2013-02-08 | 2015-09-29 | The Procter & Gamble Company | Cosmetic compositions containing substituted azole and methods for alleviating the signs of photoaged skin |
| US9138393B2 (en) | 2013-02-08 | 2015-09-22 | The Procter & Gamble Company | Cosmetic compositions containing substituted azole and methods for improving the appearance of aging skin |
| GB201317005D0 (en) * | 2013-09-25 | 2013-11-06 | Blueberry Therapeutics Ltd | Composition and methods of treatment |
| EP2952208A1 (en) * | 2014-06-04 | 2015-12-09 | Universidade de Santiago de Compostela | Hydroalcoholic system for nail treatment |
| CN109862882A (zh) * | 2016-08-29 | 2019-06-07 | 卡尔·F·尚巴赫 | 用于治疗皮肤真菌感染的方法和组合物 |
| US11554108B2 (en) | 2016-08-29 | 2023-01-17 | Xeropedix, Inc. | Methods and compositions for treating cutaneous fungal infections |
| RU2699653C1 (ru) * | 2019-03-22 | 2019-09-09 | федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) (ФГАОУ ВО Первый МГМУ им. И.М. Сеченова Минздрава России (Се | Средство для лечения микоза ногтей |
| WO2021072027A1 (en) * | 2019-10-08 | 2021-04-15 | Hallux Inc. | Onychomycosis treatment compositions and methods |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3382151A (en) * | 1964-01-13 | 1968-05-07 | Mavala Sa | Composition for strengthening nails |
| DE3544983A1 (de) * | 1985-12-19 | 1987-06-25 | Hoechst Ag | Antimykotisch wirksamer nagellack |
| US4820724A (en) * | 1986-03-31 | 1989-04-11 | University Of Southern California | Dual phase solvent carrier system |
| US4894375A (en) * | 1986-09-29 | 1990-01-16 | Merck & Co., Inc. | Method of controlling mycotic infections and compositions therefor |
| FR2673537B1 (fr) * | 1991-03-08 | 1993-06-11 | Oreal | Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes. |
| US5487776A (en) * | 1994-03-17 | 1996-01-30 | Nimni; Marcel | Anti-fungal nail lacquer and method therefor |
| US5696164A (en) * | 1994-12-22 | 1997-12-09 | Johnson & Johnson Consumer Products, Inc. | Antifungal treatment of nails |
| US5652256A (en) * | 1995-06-06 | 1997-07-29 | Knowles; W. Roy | Topical composition for fungal treatment |
| US5814308A (en) * | 1996-03-26 | 1998-09-29 | Zhang; Ke | Methods for the treatment of gastrointestinal tract disorders |
| US6030948A (en) * | 1997-12-19 | 2000-02-29 | Mann; Morris A. | Hair regeneration compositions for treatment of alopecia and methods of application related thereto |
| CA2278328C (en) * | 1998-02-09 | 2008-07-22 | Macrochem Corporation | Antifungal nail lacquer and method using same |
| CA2325553A1 (en) * | 1998-04-17 | 1999-10-28 | Penederm Inc. | Topical formulations for the treatment of nail fungal diseases |
| US6495124B1 (en) * | 2000-02-14 | 2002-12-17 | Macrochem Corporation | Antifungal nail lacquer and method using same |
| US6281239B1 (en) * | 2000-04-12 | 2001-08-28 | Bradley Pharmeaceuticals, Inc. | Method of treating onychomycosis |
| US6585963B1 (en) * | 2001-02-15 | 2003-07-01 | Watson Pharmaceuticals, Inc. | Nail compositions and methods of administering same |
| GB0108082D0 (en) * | 2001-03-30 | 2001-05-23 | Novartis Consumer Health Sa | Topical composition |
| US6765001B2 (en) * | 2001-12-21 | 2004-07-20 | Medicis Pharmaceutical Corporation | Compositions and methods for enhancing corticosteroid delivery |
| EP1635770B1 (en) * | 2003-03-21 | 2009-05-27 | Nexmed Holdings, Inc. | Antifungal nail coat and method of use |
| US20040191207A1 (en) * | 2003-03-31 | 2004-09-30 | Lipari John M. | Alpha-hydroxy acid ester drug delivery compositions and methods of use |
| HUP0303313A2 (hu) * | 2003-10-09 | 2005-07-28 | Richter Gedeon Vegyészeti Gyár Rt. | Transzdermális gyógyszerkészítmények |
-
2004
- 2004-04-27 US US10/832,933 patent/US20050238672A1/en not_active Abandoned
-
2005
- 2005-04-25 JP JP2007510881A patent/JP2007534764A/ja active Pending
- 2005-04-25 CA CA002564134A patent/CA2564134A1/en not_active Abandoned
- 2005-04-25 EP EP05739804A patent/EP1755575A4/en not_active Withdrawn
- 2005-04-25 BR BRPI0510286-3A patent/BRPI0510286A/pt not_active IP Right Cessation
- 2005-04-25 RU RU2006141653/15A patent/RU2006141653A/ru not_active Application Discontinuation
- 2005-04-25 ZA ZA200609821A patent/ZA200609821B/xx unknown
- 2005-04-25 CN CN2005800133411A patent/CN101022779B/zh not_active Expired - Fee Related
- 2005-04-25 AU AU2005237541A patent/AU2005237541A1/en not_active Abandoned
- 2005-04-25 MX MXPA06012426A patent/MXPA06012426A/es not_active Application Discontinuation
- 2005-04-25 KR KR1020067024858A patent/KR20070024543A/ko not_active Withdrawn
- 2005-04-25 WO PCT/US2005/014246 patent/WO2005105072A2/en not_active Ceased
-
2006
- 2006-10-19 IL IL178750A patent/IL178750A0/en unknown
- 2006-11-24 NO NO20065422A patent/NO20065422L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101022779B (zh) | 2010-12-08 |
| CA2564134A1 (en) | 2005-11-10 |
| WO2005105072A2 (en) | 2005-11-10 |
| IL178750A0 (en) | 2007-05-15 |
| ZA200609821B (en) | 2008-06-25 |
| EP1755575A2 (en) | 2007-02-28 |
| CN101022779A (zh) | 2007-08-22 |
| KR20070024543A (ko) | 2007-03-02 |
| JP2007534764A (ja) | 2007-11-29 |
| MXPA06012426A (es) | 2007-03-28 |
| NO20065422L (no) | 2007-01-19 |
| AU2005237541A1 (en) | 2005-11-10 |
| RU2006141653A (ru) | 2008-06-10 |
| EP1755575A4 (en) | 2010-09-22 |
| US20050238672A1 (en) | 2005-10-27 |
| WO2005105072A3 (en) | 2006-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012. |