RU2004121177A - Применение прамипексола для лечения бокового амитрофического склероза - Google Patents

Применение прамипексола для лечения бокового амитрофического склероза Download PDF

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Publication number
RU2004121177A
RU2004121177A RU2004121177/14A RU2004121177A RU2004121177A RU 2004121177 A RU2004121177 A RU 2004121177A RU 2004121177/14 A RU2004121177/14 A RU 2004121177/14A RU 2004121177 A RU2004121177 A RU 2004121177A RU 2004121177 A RU2004121177 A RU 2004121177A
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RU
Russia
Prior art keywords
pramipexole
tetrahydrobentiazole
treatment
alkyl
sclerosis
Prior art date
Application number
RU2004121177/14A
Other languages
English (en)
Russian (ru)
Inventor
Джеймс П. Мл. БЕННЕТТ (US)
Джеймс П. Мл. БЕННЕТТ
Original Assignee
Юниверсити Оф Вирджиния Пэйтент Фаундейшн (Us)
Юниверсити Оф Вирджиния Пэйтент Фаундейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Юниверсити Оф Вирджиния Пэйтент Фаундейшн (Us), Юниверсити Оф Вирджиния Пэйтент Фаундейшн filed Critical Юниверсити Оф Вирджиния Пэйтент Фаундейшн (Us)
Publication of RU2004121177A publication Critical patent/RU2004121177A/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Artificial Filaments (AREA)
  • Noodles (AREA)
RU2004121177/14A 2001-12-11 2002-12-02 Применение прамипексола для лечения бокового амитрофического склероза RU2004121177A (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US33938301P 2001-12-11 2001-12-11
US60/339,383 2001-12-11
US34737102P 2002-01-11 2002-01-11
US60/347,371 2002-01-11

Publications (1)

Publication Number Publication Date
RU2004121177A true RU2004121177A (ru) 2005-03-10

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2004121177/14A RU2004121177A (ru) 2001-12-11 2002-12-02 Применение прамипексола для лечения бокового амитрофического склероза

Country Status (20)

Country Link
US (4) US7157480B2 (da)
EP (4) EP2305252A1 (da)
JP (2) JP4500543B2 (da)
KR (1) KR20040066890A (da)
CN (1) CN1617720A (da)
AT (1) ATE480235T1 (da)
AU (1) AU2002360600B2 (da)
CA (1) CA2468747C (da)
CY (1) CY1111237T1 (da)
DE (1) DE60237635D1 (da)
DK (1) DK1453505T3 (da)
ES (2) ES2351303T3 (da)
HK (1) HK1150153A1 (da)
HU (1) HUP0500001A3 (da)
IL (1) IL162408A0 (da)
MX (1) MXPA04005572A (da)
PL (1) PL374310A1 (da)
PT (1) PT1453505E (da)
RU (1) RU2004121177A (da)
WO (1) WO2003049705A2 (da)

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US8518926B2 (en) * 2006-04-10 2013-08-27 Knopp Neurosciences, Inc. Compositions and methods of using (R)-pramipexole
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US8524695B2 (en) * 2006-12-14 2013-09-03 Knopp Neurosciences, Inc. Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
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CN102802418A (zh) * 2009-06-19 2012-11-28 诺普神经科学股份有限公司 用于治疗肌萎缩性侧索硬化的组合物和方法
WO2013096816A1 (en) 2011-12-22 2013-06-27 Biogen Idec Ma Inc. Improved synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
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CA2885653A1 (en) * 2012-11-29 2014-06-05 Wayne State University Neuroprotective agents for treatment of neurodegenerative diseases
US9662313B2 (en) 2013-02-28 2017-05-30 Knopp Biosciences Llc Compositions and methods for treating amyotrophic lateral sclerosis in responders
US9468630B2 (en) 2013-07-12 2016-10-18 Knopp Biosciences Llc Compositions and methods for treating conditions related to increased eosinophils
CN105764507B (zh) 2013-07-12 2019-07-19 诺普生物科学有限责任公司 治疗升高的嗜酸性粒细胞和/或嗜碱性粒细胞的水平
ES2871556T3 (es) 2013-08-13 2021-10-29 Knopp Biosciences Llc Composiciones y métodos para el tratamiento de la urticaria crónica
ES2813674T3 (es) 2013-08-13 2021-03-24 Knopp Biosciences Llc Composiciones y métodos para el tratamiento de trastornos de células plasmáticas y trastornos prolinfocíticos de células b
EP3681474A1 (en) 2017-09-11 2020-07-22 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Compositions and methods for nasal administration of drugs to brain and for systemic effect

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Also Published As

Publication number Publication date
DE60237635D1 (de) 2010-10-21
US20110301210A1 (en) 2011-12-08
US20070105918A1 (en) 2007-05-10
EP2305252A1 (en) 2011-04-06
CA2468747C (en) 2011-05-31
IL162408A0 (en) 2005-11-20
EP1453505B1 (en) 2010-09-08
EP1453505A2 (en) 2004-09-08
EP1453505A4 (en) 2007-01-10
CA2468747A1 (en) 2003-06-19
HUP0500001A3 (en) 2005-11-28
PT1453505E (pt) 2010-12-16
ATE480235T1 (de) 2010-09-15
HUP0500001A2 (hu) 2005-04-28
MXPA04005572A (es) 2004-12-06
CN1617720A (zh) 2005-05-18
CY1111237T1 (el) 2015-06-11
KR20040066890A (ko) 2004-07-27
EP2246053B1 (en) 2013-09-18
JP2005516911A (ja) 2005-06-09
PL374310A1 (en) 2005-10-03
AU2002360600B2 (en) 2007-11-29
DK1453505T3 (da) 2010-11-15
US20130172394A1 (en) 2013-07-04
EP2246053A1 (en) 2010-11-03
US7157480B2 (en) 2007-01-02
US20050032856A1 (en) 2005-02-10
JP2010031059A (ja) 2010-02-12
EP2305253A1 (en) 2011-04-06
ES2351303T3 (es) 2011-02-02
HK1150153A1 (en) 2011-11-04
JP4500543B2 (ja) 2010-07-14
AU2002360600A1 (en) 2003-06-23
ES2432527T3 (es) 2013-12-04
WO2003049705A2 (en) 2003-06-19
WO2003049705A3 (en) 2004-01-29

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