RU1797609C - Способ получени 5Н-дибенз ( @ , @ )-азепина - Google Patents

Способ получени 5Н-дибенз ( @ , @ )-азепина

Info

Publication number
RU1797609C
RU1797609C SU904830088A SU4830088A RU1797609C RU 1797609 C RU1797609 C RU 1797609C SU 904830088 A SU904830088 A SU 904830088A SU 4830088 A SU4830088 A SU 4830088A RU 1797609 C RU1797609 C RU 1797609C
Authority
RU
Russia
Prior art keywords
dibenz
azepine
boiling point
preparing
polar
Prior art date
Application number
SU904830088A
Other languages
English (en)
Inventor
Циаки Золтан
Хорват Андраш
Короди ФЕРЕНЦ
Кехедьи Имре
Сабо Золтан
Тимар Тибор
Франк Ласло
Галамб Вилмош
Балог Корик Пирошка
Фекете Миклош
Хорват Шандор
Юхас Карой
Тамаш Лайош
Теребеш Ласло
Original Assignee
Алкалоида Ведьесети Дьяр
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Алкалоида Ведьесети Дьяр filed Critical Алкалоида Ведьесети Дьяр
Application granted granted Critical
Publication of RU1797609C publication Critical patent/RU1797609C/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Использование: в качестве промежуточного вещества дл  синтеза лекарственных средств, например карбамазепина, про вл ющего антиэпилептичеекую активность. Сущность изобретени : продукт: 5Н-дибенз (b,f) азепин, Реагент 1: иминадибензил, Услови  реакции: каталитическа  дегидрогенизаци  в присутствии катализатора из благородного металла и от 0,35 до 2 мол рных эквивалентов акцептора водорода при 200-270°С, в расплаве без растворител  или в жидком состо нии в пол рном протонном растворителе с высокой температурой кипени , или в смеси с непол рным растворителем , имеющим более высокую температуру кипени . (Л С
SU904830088A 1989-05-04 1990-05-04 Способ получени 5Н-дибенз ( @ , @ )-азепина RU1797609C (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU892158A HU206682B (en) 1989-05-04 1989-05-04 Improved process for producing 5h-dibenz/b,f/azepine

Publications (1)

Publication Number Publication Date
RU1797609C true RU1797609C (ru) 1993-02-23

Family

ID=10958059

Family Applications (1)

Application Number Title Priority Date Filing Date
SU904830088A RU1797609C (ru) 1989-05-04 1990-05-04 Способ получени 5Н-дибенз ( @ , @ )-азепина

Country Status (9)

Country Link
EP (1) EP0396134A1 (ru)
JP (1) JPH0356465A (ru)
KR (1) KR930011490B1 (ru)
DD (1) DD294247A5 (ru)
HU (1) HU206682B (ru)
IL (1) IL94271A (ru)
PL (1) PL163638B1 (ru)
RU (1) RU1797609C (ru)
YU (1) YU47006B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU663580B2 (en) * 1992-05-13 1995-10-12 Novartis Ag Preparation of iminostilbene by high-temperature dehydrogenation
AT401772B (de) 1994-12-27 1996-11-25 Chemie Linz Gmbh Verfahren zur reinigung von 5h-dibenzo-(b,f)-azepin
AT409628B (de) * 2000-04-10 2002-09-25 Dsm Fine Chem Austria Gmbh Reinigungsverfahren zur herstellung von hochreinem 5h-dibenzo-(b,f)-azepin
CN101307021B (zh) * 2008-07-04 2010-06-23 浙江工业大学 一种亚氨基芪的化学合成方法
CN105439954A (zh) * 2014-09-25 2016-03-30 中国石油化工股份有限公司 一种亚氨基芪的单步合成方法
CN105566223A (zh) * 2014-10-17 2016-05-11 中国石油化工股份有限公司 一种亚氨基芪粗品重结晶方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3074931A (en) * 1963-01-22 Dibenzazepines
FI74276C (fi) * 1986-03-14 1988-01-11 Orion Yhtymae Oy Ett nytt foerfarande foer framstaellning av 5h-dibenso-(b, f)-azepin.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Европейский патент № 0237952, кл. С 07 0223/22,1987. *

Also Published As

Publication number Publication date
HU206682B (en) 1992-12-28
JPH0356465A (ja) 1991-03-12
DD294247A5 (de) 1991-09-26
IL94271A (en) 1994-04-12
KR900018038A (ko) 1990-12-20
YU47006B (sh) 1994-11-15
IL94271A0 (en) 1991-03-10
PL285047A1 (en) 1991-01-14
EP0396134A1 (de) 1990-11-07
PL163638B1 (pl) 1994-04-29
HUT54994A (en) 1991-04-29
KR930011490B1 (ko) 1993-12-08

Similar Documents

Publication Publication Date Title
Hartman et al. Catalytic hydration of alkynes with platinum (II) complexes
Murahashi et al. Ruthenium-catalysed oxidation of secondary amines to imines using t-butyl hydroperoxide
CA2194034A1 (en) Production of terephthalic acid with excellent optical properties through the use of pure or nearly pure oxygen as the oxidant in p-xylene oxidation
MY111427A (en) The preparation of caprolactam.
ES8707516A1 (es) Procedimiento para la produccion de gamma-butirolactona.
RU1797609C (ru) Способ получени 5Н-дибенз ( @ , @ )-азепина
AU5268193A (en) Process for the preparation of 2-alkyl-6-methyl-N-(1'-methoxy-2'-propyl)-aniline and a process for the preparation of their chloracetanilides
KR970001290A (ko) 디플루오로메탄의 제조방법
JPS6470446A (en) Production of cyclohexylamine
FI74276C (fi) Ett nytt foerfarande foer framstaellning av 5h-dibenso-(b, f)-azepin.
NO991140D0 (no) Fischer-Tropsch-katalysator og fremgangsmÕte for fremstilling av hydrokarboner
KR920009766A (ko) 아세트산 및 아세트산 무수물을 동시에 제조하는 연속 방법
ES2016674B3 (es) Procedimiento de fabricacion de gas de sintesis o de hidrogeno por conversion catalitica del metanol en fase liquida.
NO990890D0 (no) Prosess for produksjon av kontrastmidler
RU1836352C (ru) Способ получени 5-карбамоил-5н-дибенз[ @ , @ ]азепина
KR970001289A (ko) 디플루오로메탄의 제조방법
EP0748305B1 (en) Catalyst and process for alkylation of aromatics
NO308598B1 (no) FremgangsmÕte for fremstilling av kaprolaktam
GB2165844A (en) Pyridine from 1,3-propane dinitrile
Reddy et al. A novel protocol for N-methyl-γ-amino-β-hydroxy acids from oxazolidinones
KR970042490A (ko) 시클로프로판카르복실산 아미드의 제조방법
EP0493778A1 (en) Process for the catalytic mono-epoxidation of diolefins
TH9818A (th) กรรมวิธีเตรียม 5H-ไดเบนซ์ [b;f] แอซิพีน ซึ่งปรับปรุงให้ดีขึ้น
SU1567563A1 (ru) Способ дехлорировани 1,1,1-трихлор-2,2-бис-( @ -хлорфенил)этана или 1,1-дихлор-2,2-бис-( @ -хлорфенил)этана
KR19990014859A (ko) 6-아미노카프로니트릴의 카프롤락탐으로의 이산화티탄 촉매에의한 액상 고리화법