RS66214B1 - Kokristali (1r,3s)-3-(5-cijano-4-fenil-1,3-tiazol-2-ilkarbamoil)ciklopentan karboksilne kiseline - Google Patents

Kokristali (1r,3s)-3-(5-cijano-4-fenil-1,3-tiazol-2-ilkarbamoil)ciklopentan karboksilne kiseline

Info

Publication number
RS66214B1
RS66214B1 RS20241203A RSP20241203A RS66214B1 RS 66214 B1 RS66214 B1 RS 66214B1 RS 20241203 A RS20241203 A RS 20241203A RS P20241203 A RSP20241203 A RS P20241203A RS 66214 B1 RS66214 B1 RS 66214B1
Authority
RS
Serbia
Prior art keywords
crystal
cyano
ylcarbamoyl
thiazol
phenyl
Prior art date
Application number
RS20241203A
Other languages
English (en)
Serbian (sr)
Inventor
Laria Julio Castro Palomino
Gómez Juan Camacho
Original Assignee
Palobiofarma Sl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Palobiofarma Sl filed Critical Palobiofarma Sl
Publication of RS66214B1 publication Critical patent/RS66214B1/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/02Salts; Complexes; Addition compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/03Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
    • C07C65/05Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring o-Hydroxy carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RS20241203A 2020-03-16 2021-03-15 Kokristali (1r,3s)-3-(5-cijano-4-fenil-1,3-tiazol-2-ilkarbamoil)ciklopentan karboksilne kiseline RS66214B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20382194.7A EP3882240A1 (en) 2020-03-16 2020-03-16 Cocrystals of (1r,3s)-3-(5-cyano-4-phenyl-1,3-thiazol-2-ylcabamoyl)cyclopentane carboxylic acid
EP21710531.1A EP4121419B1 (en) 2020-03-16 2021-03-15 Cocrystals of (1r,3s)-3-(5-cyano-4-phenyl-1,3-thiazol-2-ylcarbamoyl)cyclopentane carboxylic acid
PCT/EP2021/056506 WO2021185748A1 (en) 2020-03-16 2021-03-15 Cocrystals of (1r,3s)-3-(5-cyano-4-phenyl-1,3-thiazol-2-ylcabamoyl)cyclopentane carboxylic acid

Publications (1)

Publication Number Publication Date
RS66214B1 true RS66214B1 (sr) 2024-12-31

Family

ID=69953938

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20241203A RS66214B1 (sr) 2020-03-16 2021-03-15 Kokristali (1r,3s)-3-(5-cijano-4-fenil-1,3-tiazol-2-ilkarbamoil)ciklopentan karboksilne kiseline

Country Status (21)

Country Link
US (1) US12384754B2 (https=)
EP (2) EP3882240A1 (https=)
JP (1) JP7779846B2 (https=)
KR (1) KR20220154791A (https=)
CN (1) CN115298169B (https=)
AU (1) AU2021237686B2 (https=)
BR (1) BR112022018449A2 (https=)
CA (1) CA3171894C (https=)
DK (1) DK4121419T3 (https=)
ES (1) ES3002084T3 (https=)
FI (1) FI4121419T3 (https=)
HR (1) HRP20241515T1 (https=)
HU (1) HUE068886T2 (https=)
LT (1) LT4121419T (https=)
MX (1) MX2022011530A (https=)
PL (1) PL4121419T3 (https=)
PT (1) PT4121419T (https=)
RS (1) RS66214B1 (https=)
SI (1) SI4121419T1 (https=)
WO (1) WO2021185748A1 (https=)
ZA (1) ZA202211247B (https=)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2331220B1 (es) 2007-10-02 2010-09-23 Palobiofarma, S.L. Nuevos compuestos como antagonistas de los receptores a1 de adenosina.
US8779146B2 (en) 2010-04-28 2014-07-15 Nuformix Limited Cilostazol cocrystals and compositions
LT3592734T (lt) 2017-03-06 2021-07-26 Palobiofarma, S.L. (1r,3s)-3-(5-ciano-4-fenil-1,3-tiazol-2-ilkarbamoil)ciklopentankarboksirūgšties amino druska

Also Published As

Publication number Publication date
ES3002084T3 (en) 2025-03-06
JP7779846B2 (ja) 2025-12-03
KR20220154791A (ko) 2022-11-22
MX2022011530A (es) 2022-10-13
HUE068886T2 (hu) 2025-02-28
EP4121419A1 (en) 2023-01-25
CN115298169A (zh) 2022-11-04
FI4121419T3 (fi) 2024-11-04
US12384754B2 (en) 2025-08-12
LT4121419T (lt) 2024-11-25
CA3171894C (en) 2025-03-11
EP3882240A1 (en) 2021-09-22
WO2021185748A1 (en) 2021-09-23
CN115298169B (zh) 2024-11-19
US20230183195A1 (en) 2023-06-15
DK4121419T3 (da) 2024-10-28
ZA202211247B (en) 2023-12-20
AU2021237686A1 (en) 2022-10-06
BR112022018449A2 (pt) 2022-11-01
AU2021237686B2 (en) 2026-04-09
HRP20241515T1 (hr) 2025-01-03
PL4121419T3 (pl) 2025-02-17
CA3171894A1 (en) 2021-09-23
EP4121419B1 (en) 2024-08-14
PT4121419T (pt) 2024-11-18
SI4121419T1 (sl) 2025-02-28
JP2023517722A (ja) 2023-04-26

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