RS62705B1 - Poboljšani postupak za pripremanje imetelstata - Google Patents

Poboljšani postupak za pripremanje imetelstata

Info

Publication number
RS62705B1
RS62705B1 RS20211534A RSP20211534A RS62705B1 RS 62705 B1 RS62705 B1 RS 62705B1 RS 20211534 A RS20211534 A RS 20211534A RS P20211534 A RSP20211534 A RS P20211534A RS 62705 B1 RS62705 B1 RS 62705B1
Authority
RS
Serbia
Prior art keywords
imetelstat
preparing
improved process
improved
preparing imetelstat
Prior art date
Application number
RS20211534A
Other languages
English (en)
Inventor
Jale Muslehiddinoglu
Dinesh Gala
Jennifer Elizabeth Albaneze-Walker
Original Assignee
Geron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geron Corp filed Critical Geron Corp
Publication of RS62705B1 publication Critical patent/RS62705B1/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Specially Adapted For Manufacturing Cables (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RS20211534A 2017-07-10 2018-07-09 Poboljšani postupak za pripremanje imetelstata RS62705B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17180426 2017-07-10
EP18737621.5A EP3652187B1 (en) 2017-07-10 2018-07-09 Improved process for preparing imetelstat
PCT/EP2018/068485 WO2019011829A1 (en) 2017-07-10 2018-07-09 IMPROVED METHOD FOR PREPARING IMETELSTAT

Publications (1)

Publication Number Publication Date
RS62705B1 true RS62705B1 (sr) 2022-01-31

Family

ID=59313083

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20211534A RS62705B1 (sr) 2017-07-10 2018-07-09 Poboljšani postupak za pripremanje imetelstata

Country Status (29)

Country Link
US (4) US11332489B2 (sr)
EP (1) EP3652187B1 (sr)
JP (2) JP7199410B2 (sr)
KR (1) KR20200035267A (sr)
CN (1) CN110891961B (sr)
AU (2) AU2018298658B2 (sr)
BR (1) BR112020000410A2 (sr)
CA (2) CA3066968C (sr)
CL (1) CL2020000054A1 (sr)
CO (1) CO2020000096A2 (sr)
CY (1) CY1125351T1 (sr)
DK (1) DK3652187T3 (sr)
EA (1) EA038579B1 (sr)
ES (1) ES2901099T3 (sr)
HR (1) HRP20211940T1 (sr)
HU (1) HUE056722T2 (sr)
IL (1) IL271388B (sr)
LT (1) LT3652187T (sr)
MA (1) MA49555A (sr)
PL (1) PL3652187T3 (sr)
PT (1) PT3652187T (sr)
RS (1) RS62705B1 (sr)
SA (1) SA520410996B1 (sr)
SG (1) SG11201912385VA (sr)
SI (1) SI3652187T1 (sr)
TW (1) TWI775895B (sr)
UA (1) UA125185C2 (sr)
WO (1) WO2019011829A1 (sr)
ZA (1) ZA201908452B (sr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11530179B2 (en) * 2019-10-28 2022-12-20 Geron Corporation Amorphous solid succinylated 3-(fatty acid amido)-2-hydroxy-1 -(protected hydroxy)-propane salts and methods of making the same
AU2020375734A1 (en) 2019-10-28 2022-05-26 Geron Corporation Crystalline solids of 3-palmitoyl-amido-1,2-propanediol and 3-palmitoyl-amido-2-hydroxy-1-dimethoxytriphenylmethylether-propane and methods of making and using the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1210357T3 (da) 1999-09-10 2008-07-21 Geron Corp Oligonukleotid-N3' -P5' -thiophosphoramidater: syntese og anvendelse deraf
AU2004271215B2 (en) 2003-09-09 2009-07-16 Geron Corporation Modified oligonucleotides for telomerase inhibition
US7485717B2 (en) 2004-07-02 2009-02-03 Geron Corporation Synthesis of protected 3′-amino nucleoside monomers
KR20120093138A (ko) 2009-06-17 2012-08-22 콜드스프링하버러보러토리 대상에게서 smn2 스플라이싱을 조정하기 위한 조성물 및 방법
JOP20200257A1 (ar) 2014-05-01 2017-06-16 Geron Corp تركيبات أوليجو نوكليوتيد وطرق لتحضيرها
US11142545B2 (en) 2016-06-24 2021-10-12 Biogen Ma Inc. Synthesis of thiolated oligonucleotides without a capping step

Also Published As

Publication number Publication date
HUE056722T2 (hu) 2022-03-28
AU2018298658A1 (en) 2020-01-23
PL3652187T3 (pl) 2022-01-31
CA3066968A1 (en) 2019-01-17
CO2020000096A2 (es) 2020-01-17
EP3652187A1 (en) 2020-05-20
SG11201912385VA (en) 2020-01-30
CA3195922A1 (en) 2019-01-17
MA49555A (fr) 2021-04-28
WO2019011829A1 (en) 2019-01-17
BR112020000410A2 (pt) 2020-07-14
SA520410996B1 (ar) 2023-12-05
LT3652187T (lt) 2022-01-25
IL271388A (en) 2020-01-30
JP7199410B2 (ja) 2023-01-05
EA202090006A1 (ru) 2020-05-18
JP2020526524A (ja) 2020-08-31
SI3652187T1 (sl) 2022-01-31
KR20200035267A (ko) 2020-04-02
ES2901099T3 (es) 2022-03-21
CN110891961B (zh) 2023-06-30
US20240262854A1 (en) 2024-08-08
IL271388B (en) 2022-03-01
ZA201908452B (en) 2022-03-30
DK3652187T3 (da) 2021-12-13
JP2022183382A (ja) 2022-12-08
US11332489B2 (en) 2022-05-17
PT3652187T (pt) 2021-12-16
AU2018298658B2 (en) 2022-09-29
AU2022291626A1 (en) 2023-02-02
US20230070069A1 (en) 2023-03-09
US20240199672A1 (en) 2024-06-20
HRP20211940T1 (hr) 2022-03-18
CN110891961A (zh) 2020-03-17
UA125185C2 (uk) 2022-01-26
TWI775895B (zh) 2022-09-01
CL2020000054A1 (es) 2020-10-02
CY1125351T1 (el) 2023-03-24
US20200369702A1 (en) 2020-11-26
CA3066968C (en) 2023-06-13
EA038579B1 (ru) 2021-09-17
TW201920228A (zh) 2019-06-01
EP3652187B1 (en) 2021-09-15

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