MA49555A - Procédé amélioré de préparation d'imetelstat - Google Patents

Procédé amélioré de préparation d'imetelstat

Info

Publication number
MA49555A
MA49555A MA049555A MA49555A MA49555A MA 49555 A MA49555 A MA 49555A MA 049555 A MA049555 A MA 049555A MA 49555 A MA49555 A MA 49555A MA 49555 A MA49555 A MA 49555A
Authority
MA
Morocco
Prior art keywords
imetelstat
improved
preparation process
preparation
improved imetelstat
Prior art date
Application number
MA049555A
Other languages
English (en)
Inventor
Jennifer Elizabeth Albaneze-Walker
Dinesh Gala
Jale Muslehiddinoglu
Original Assignee
Geron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geron Corp filed Critical Geron Corp
Publication of MA49555A publication Critical patent/MA49555A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Specially Adapted For Manufacturing Cables (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA049555A 2017-07-10 2018-07-09 Procédé amélioré de préparation d'imetelstat MA49555A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17180426 2017-07-10

Publications (1)

Publication Number Publication Date
MA49555A true MA49555A (fr) 2021-04-28

Family

ID=59313083

Family Applications (1)

Application Number Title Priority Date Filing Date
MA049555A MA49555A (fr) 2017-07-10 2018-07-09 Procédé amélioré de préparation d'imetelstat

Country Status (28)

Country Link
US (4) US11332489B2 (fr)
EP (1) EP3652187B1 (fr)
JP (2) JP7199410B2 (fr)
CN (1) CN110891961B (fr)
AU (2) AU2018298658B2 (fr)
BR (1) BR112020000410A2 (fr)
CA (2) CA3195922A1 (fr)
CL (1) CL2020000054A1 (fr)
CO (1) CO2020000096A2 (fr)
CY (1) CY1125351T1 (fr)
DK (1) DK3652187T3 (fr)
EA (1) EA038579B1 (fr)
ES (1) ES2901099T3 (fr)
HR (1) HRP20211940T1 (fr)
HU (1) HUE056722T2 (fr)
IL (1) IL271388B (fr)
LT (1) LT3652187T (fr)
MA (1) MA49555A (fr)
PL (1) PL3652187T3 (fr)
PT (1) PT3652187T (fr)
RS (1) RS62705B1 (fr)
SA (1) SA520410996B1 (fr)
SG (1) SG11201912385VA (fr)
SI (1) SI3652187T1 (fr)
TW (1) TWI775895B (fr)
UA (1) UA125185C2 (fr)
WO (1) WO2019011829A1 (fr)
ZA (1) ZA201908452B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3155391A1 (fr) 2019-10-28 2021-05-06 Geron Corporation Solides cristallins de 3-palmitoyl-amido -1,2-propanediol et de 3-palmitoyl-amido-2-hydroxy-1-dimethoxytriphenylmethyl ether-propane et leurs procedes de fabrication et d'utilisatio
WO2021086753A1 (fr) * 2019-10-28 2021-05-06 Geron Corporation Sels solides amorphes de 3-(acide gras amido)-2-hydroxy-1-(hydroxy protégé)-propane succinylés et leurs procédés de fabrication

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1210357E (pt) * 1999-09-10 2008-06-11 Geron Corp Oligonucleótido-tiofosforamidatos n3'→p5': sua síntese e utilização
KR101319388B1 (ko) 2003-09-09 2013-10-22 제론 코포레이션 텔로머라제 억제를 위한 변형 올리고뉴클레오티드
ME02933B (fr) 2004-07-02 2018-04-20 Geron Corp Synthese de monomeres nucleosidiques a groupe 3'-amino protege
NZ597071A (en) 2009-06-17 2014-05-30 Isis Pharmaceuticals Inc Compositions and methods for modulation of smn2 splicing in a subject
JOP20200257A1 (ar) * 2014-05-01 2017-06-16 Geron Corp تركيبات أوليجو نوكليوتيد وطرق لتحضيرها
KR20190020743A (ko) 2016-06-24 2019-03-04 바이오젠 엠에이 인코포레이티드 캡핑 단계 없이 티올화된 올리고뉴클레오타이드의 합성

Also Published As

Publication number Publication date
CL2020000054A1 (es) 2020-10-02
EP3652187B1 (fr) 2021-09-15
KR20200035267A (ko) 2020-04-02
US20230070069A1 (en) 2023-03-09
DK3652187T3 (da) 2021-12-13
JP2022183382A (ja) 2022-12-08
JP2020526524A (ja) 2020-08-31
CN110891961B (zh) 2023-06-30
AU2022291626A1 (en) 2023-02-02
US20200369702A1 (en) 2020-11-26
PL3652187T3 (pl) 2022-01-31
IL271388B (en) 2022-03-01
CA3066968C (fr) 2023-06-13
EA202090006A1 (ru) 2020-05-18
ZA201908452B (en) 2022-03-30
EP3652187A1 (fr) 2020-05-20
AU2018298658B2 (en) 2022-09-29
PT3652187T (pt) 2021-12-16
HUE056722T2 (hu) 2022-03-28
WO2019011829A1 (fr) 2019-01-17
SG11201912385VA (en) 2020-01-30
CY1125351T1 (el) 2023-03-24
BR112020000410A2 (pt) 2020-07-14
HRP20211940T1 (hr) 2022-03-18
CA3066968A1 (fr) 2019-01-17
TW201920228A (zh) 2019-06-01
JP7199410B2 (ja) 2023-01-05
SI3652187T1 (sl) 2022-01-31
EA038579B1 (ru) 2021-09-17
CO2020000096A2 (es) 2020-01-17
LT3652187T (lt) 2022-01-25
CN110891961A (zh) 2020-03-17
UA125185C2 (uk) 2022-01-26
CA3195922A1 (en) 2019-01-17
SA520410996B1 (ar) 2023-12-05
ES2901099T3 (es) 2022-03-21
US20240199672A1 (en) 2024-06-20
US20240262854A1 (en) 2024-08-08
US11332489B2 (en) 2022-05-17
IL271388A (en) 2020-01-30
TWI775895B (zh) 2022-09-01
AU2018298658A1 (en) 2020-01-23
RS62705B1 (sr) 2022-01-31

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