RS61214B1 - Toplotno-sterilisana formulacija koja sadrži hitozan i proces njene pripreme - Google Patents

Toplotno-sterilisana formulacija koja sadrži hitozan i proces njene pripreme

Info

Publication number
RS61214B1
RS61214B1 RS20201504A RSP20201504A RS61214B1 RS 61214 B1 RS61214 B1 RS 61214B1 RS 20201504 A RS20201504 A RS 20201504A RS P20201504 A RSP20201504 A RS P20201504A RS 61214 B1 RS61214 B1 RS 61214B1
Authority
RS
Serbia
Prior art keywords
chitosan
composition
glycerol
kda
heat
Prior art date
Application number
RS20201504A
Other languages
English (en)
Serbian (sr)
Inventor
Leila Yolanda Bossy
Napoli Alessandro Di
Original Assignee
Laboratoire Medidom S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Medidom S A filed Critical Laboratoire Medidom S A
Publication of RS61214B1 publication Critical patent/RS61214B1/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/04—Oxygen-containing compounds
    • C08K5/05—Alcohols; Metal alcoholates
    • C08K5/053—Polyhydroxylic alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/719—Pullulans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/722—Chitin, chitosan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L3/00—Compositions of starch, amylose or amylopectin or of their derivatives or degradation products
    • C08L3/12—Amylose; Amylopectin; Degradation products thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/21—Pharmaceuticals, e.g. medicaments, artificial body parts
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2201/00—Properties
    • C08L2201/10—Transparent films; Clear coatings; Transparent materials
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2201/00—Properties
    • C08L2201/54—Aqueous solutions or dispersions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00—Applications
    • C08L2203/02—Applications for biomedical use
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/02—Polymer mixtures characterised by other features containing two or more polymers of the same C08L -group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RS20201504A 2014-10-29 2015-10-28 Toplotno-sterilisana formulacija koja sadrži hitozan i proces njene pripreme RS61214B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/EP2014/073246 WO2016066195A1 (en) 2014-10-29 2014-10-29 Heat-sterilized formulation comprising chitosan and process of preparation thereof
PCT/IB2015/058300 WO2016067210A1 (en) 2014-10-29 2015-10-28 Heat-sterilized formulation comprising chitosan and process of preparation thereof
EP15798206.7A EP3212166B1 (en) 2014-10-29 2015-10-28 Heat-sterilized formulation comprising chitosan and process of preparation thereof

Publications (1)

Publication Number Publication Date
RS61214B1 true RS61214B1 (sr) 2021-01-29

Family

ID=51842529

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20201504A RS61214B1 (sr) 2014-10-29 2015-10-28 Toplotno-sterilisana formulacija koja sadrži hitozan i proces njene pripreme

Country Status (17)

Country Link
US (1) US10493155B2 (enExample)
EP (1) EP3212166B1 (enExample)
JP (1) JP6814133B2 (enExample)
KR (1) KR102421423B1 (enExample)
CN (1) CN107075174B (enExample)
CA (1) CA2965447C (enExample)
CO (1) CO2017003840A2 (enExample)
DK (1) DK3212166T3 (enExample)
ES (1) ES2857273T3 (enExample)
HR (1) HRP20201995T1 (enExample)
HU (1) HUE053432T2 (enExample)
MX (1) MX383011B (enExample)
PT (1) PT3212166T (enExample)
RS (1) RS61214B1 (enExample)
RU (1) RU2712271C2 (enExample)
SI (1) SI3212166T1 (enExample)
WO (2) WO2016066195A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9463201B2 (en) 2014-10-19 2016-10-11 M.G. Therapeutics Ltd Compositions and methods for the treatment of meibomian gland dysfunction
MA44676A (fr) 2016-04-14 2019-02-20 Azura Ophthalmics Ltd Compositions de disulfure de sélénium destinées à être utilisées dans le traitement du dysfonctionnement de la glande de meibomius
US10576099B2 (en) 2016-10-21 2020-03-03 Covidien Lp Injectable scaffold for treatment of intracranial aneurysms and related technology
US11452783B2 (en) * 2017-02-14 2022-09-27 Gi Supply Tissue stain and use thereof
EP3952881A4 (en) * 2019-04-12 2023-01-04 Azura Ophthalmics Ltd. COMPOSITIONS AND METHODS FOR THE TREATMENT OF CONTACT LENS DISCOMFORT
CN114630627A (zh) 2019-11-04 2022-06-14 柯惠有限合伙公司 用于治疗颅内动脉瘤的装置、系统和方法
JP7453036B2 (ja) * 2020-03-30 2024-03-19 株式会社ナリス化粧品 皮膚外用剤
CN114652866A (zh) * 2020-12-23 2022-06-24 上海其胜生物制剂有限公司 一种羧甲基几丁质溶液的湿热灭菌方法
WO2022198208A1 (en) 2021-03-16 2022-09-22 Covidien Lp Injectable biopolymer compositions and associated systems and methods

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659700A (en) * 1984-03-02 1987-04-21 Johnson & Johnson Products, Inc. Chitosan-glycerol-water gel
JPS6462302A (en) * 1987-09-01 1989-03-08 Nippon Suisan Kaisha Ltd Water-soluble chitosan salt and production thereof
JPH06107551A (ja) * 1992-09-30 1994-04-19 Hisamitsu Pharmaceut Co Inc 関節症治療剤
JPH07118304A (ja) * 1993-10-27 1995-05-09 Asahi Glass Co Ltd キトサン水溶液
US5420197A (en) * 1994-01-13 1995-05-30 Hydromer, Inc. Gels formed by the interaction of polyvinylpyrrolidone with chitosan derivatives
AU6742696A (en) 1995-08-17 1997-03-12 Ciba-Geigy Ag Stabilized chitin derivative compounds
DE69828451T2 (de) * 1998-11-20 2006-01-12 Laboratoire Medidom S.A. Wässrige ophthalmische formulierungen mit chitosan
JP5116129B2 (ja) * 2000-09-01 2013-01-09 日本水産株式会社 中性付近のキトサン水溶液の製造法
US20020119949A1 (en) * 2001-02-26 2002-08-29 Asa Hellman Prophylactic teat treatment
KR100674672B1 (ko) * 2002-10-08 2007-01-29 가부시끼가이샤 리코무 키토산 함유 다당, 그 제조방법 및 용도
SI1978925T1 (sl) * 2005-12-23 2010-01-29 Medidom Lab Termoreaktiven nevtraliziran sestavek hitozana, ki tvori hidrogel, liofilizat in postopek za izdelavo le-tega
US9034348B2 (en) * 2006-12-11 2015-05-19 Chi2Gel Ltd. Injectable chitosan mixtures forming hydrogels
US20090142292A1 (en) * 2007-12-03 2009-06-04 Blackwell Richard I Method For The Mitigation of Symptoms of Dry Eye

Also Published As

Publication number Publication date
JP6814133B2 (ja) 2021-01-13
EP3212166A1 (en) 2017-09-06
CA2965447C (en) 2022-05-31
US20170312364A1 (en) 2017-11-02
SI3212166T1 (sl) 2021-01-29
CA2965447A1 (en) 2016-05-06
RU2017118261A3 (enExample) 2019-04-25
CO2017003840A2 (es) 2017-04-28
RU2017118261A (ru) 2018-11-29
CN107075174B (zh) 2021-03-30
DK3212166T3 (da) 2021-02-22
WO2016067210A1 (en) 2016-05-06
HRP20201995T1 (hr) 2021-02-05
RU2712271C2 (ru) 2020-01-28
WO2016066195A1 (en) 2016-05-06
PT3212166T (pt) 2021-02-09
EP3212166B1 (en) 2020-12-02
JP2017533186A (ja) 2017-11-09
US10493155B2 (en) 2019-12-03
BR112017008353A2 (pt) 2017-12-19
CN107075174A (zh) 2017-08-18
ES2857273T3 (es) 2021-09-28
MX2017004760A (es) 2017-07-26
HUE053432T2 (hu) 2021-07-28
MX383011B (es) 2025-03-13
KR20170076659A (ko) 2017-07-04
KR102421423B1 (ko) 2022-07-15

Similar Documents

Publication Publication Date Title
RU2712271C2 (ru) Содержащая хитозан композиция, стерилизованная путем нагрева, а также способ ее получения
Sun et al. Mucoadhesive phenylboronic acid conjugated chitosan oligosaccharide-vitamin E copolymer for topical ocular delivery of voriconazole: Synthesis, in vitro/vivo evaluation, and mechanism
KR20090108723A (ko) 안 약물 송달을 위한 신규한 생체적합물질 및 이의 제조방법 및 용도
CA3002384C (en) Pharmaceutical formulations that form gel in situ
CN1604784A (zh) 含有肝素的眼科制剂
CA3020772A1 (en) Anti-infective compositions comprising phytoglycogen nanoparticles
JP2020513016A (ja) 能力と安全性が増強された組成物および抗菌合成カチオン性ポリペプチド類を局所的に適用する使用
Stefan et al. The current view on biological potency of cationically modified chitosan
Lu et al. Enhanced antibacterial and antibiofilm activities of quaternized ultra-highly deacetylated chitosan against multidrug-resistant bacteria
CN116139067B (zh) 透明质酸锌形成凝胶的方法及含有透明质酸锌的滴眼凝胶及其制备
RU2404768C1 (ru) Глазные капли
WO2000030609A1 (en) Aqueous ophthalmic formulations comprising chitosan
JP3050898B2 (ja) 水性医薬製剤
KR101341647B1 (ko) 베타-글루칸을 포함하는 각결막염 치료용 점안제 조성물
EP3150211B1 (en) Therapeutic agent for keratoconjunctive disorder
CN106265720A (zh) 一种复合人工泪液及其制备方法
HK1238537A1 (en) Heat-sterilized formulation comprising chitosan and process of preparation thereof
HK1238537B (en) Heat-sterilized formulation comprising chitosan and process of preparation thereof
BR112017008353B1 (pt) Formulação termoesterilizada compreendendo quitosana e processo de preparação da mesma
CN1242811C (zh) 重组水蛭素的用途
EP4667000A1 (en) Hyperosmolar ophthalmic composition comprising carboxymethyl chitosan
Alaimo et al. Chitosan-based nanosuspensions for ocular diagnosis and therapy
Kumar et al. Healing efficiency of nystatin-loaded chitosan-guar gum-based nanocapsules in experimental fungal keratitis
Islam et al. Chitosan-based gels for ocular drug delivery
Elçin Panomycocin-incorporated chitosan-tpp nanoparticles: preparation, characterization and in vitro determination of antifungal activity against human dermatophytes