RS52638B - Inhibitori histonske deacetilaze sa spojenom aktivnosti protiv histonskih deacetilaza klase-i i klase-iib u kombinaciji sa inhibitorima proteasoma - Google Patents

Inhibitori histonske deacetilaze sa spojenom aktivnosti protiv histonskih deacetilaza klase-i i klase-iib u kombinaciji sa inhibitorima proteasoma

Info

Publication number
RS52638B
RS52638B RS20130038A RSP20130038A RS52638B RS 52638 B RS52638 B RS 52638B RS 20130038 A RS20130038 A RS 20130038A RS P20130038 A RSP20130038 A RS P20130038A RS 52638 B RS52638 B RS 52638B
Authority
RS
Serbia
Prior art keywords
class
inhibitors
combination
histone
histone deacetylase
Prior art date
Application number
RS20130038A
Other languages
English (en)
Inventor
Janine Arts
Peter Willem Jan Hellemans
Michel Marie François Janicot
Martin John Page
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Priority claimed from PCT/EP2007/059518 external-priority patent/WO2008031817A2/en
Publication of RS52638B publication Critical patent/RS52638B/sr

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Kombinacija, naznačena time, da obuhvata inhibitor proteasoma, pri čemu je pomenuti inhibitor proteasoma bortezomib, i inhibitor histonske deacetilaze, pri čemu je pomenuti inhibitor histonske deacetilaze jedinjenje Br. 1a (JNJ26481585)njegove farmaceutski prihvatljive kisele i bazne adicione soli i stereohemijski izomerne forme.Prijava sadrži još 7 patentnih zahteva.
RS20130038A 2006-09-15 2007-09-11 Inhibitori histonske deacetilaze sa spojenom aktivnosti protiv histonskih deacetilaza klase-i i klase-iib u kombinaciji sa inhibitorima proteasoma RS52638B (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06120726 2006-09-15
US91589507P 2007-05-03 2007-05-03
PCT/EP2007/059518 WO2008031817A2 (en) 2006-09-15 2007-09-11 Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors

Publications (1)

Publication Number Publication Date
RS52638B true RS52638B (sr) 2013-06-28

Family

ID=41040414

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20130038A RS52638B (sr) 2006-09-15 2007-09-11 Inhibitori histonske deacetilaze sa spojenom aktivnosti protiv histonskih deacetilaza klase-i i klase-iib u kombinaciji sa inhibitorima proteasoma

Country Status (12)

Country Link
CN (1) CN101516374B (sr)
BR (1) BRPI0716992A2 (sr)
DK (1) DK2066327T3 (sr)
ES (1) ES2399670T3 (sr)
ME (1) ME01514B (sr)
NZ (1) NZ575030A (sr)
PT (1) PT2066327E (sr)
RS (1) RS52638B (sr)
SG (1) SG177219A1 (sr)
SI (1) SI2066327T1 (sr)
UA (1) UA97249C2 (sr)
ZA (1) ZA200901818B (sr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8957066B2 (en) * 2011-02-28 2015-02-17 Biomarin Pharmaceutical Inc. Histone deacetylase inhibitors
CN107095871A (zh) * 2016-02-22 2017-08-29 中国科学院上海巴斯德研究所 Quisinostat，一种新型的高效抗疟药物
WO2018017858A1 (en) * 2016-07-20 2018-01-25 The Trustees Of Columbia University In The City Of New York Histone acetyltransferase activators and compositions and uses thereof
CN114409638B (zh) * 2022-02-09 2023-02-14 深圳大学 组蛋白去乙酰化酶8选择性降解剂、制备方法及其在抗肿瘤活性中的应用
CN115028678B (zh) * 2022-07-08 2024-09-06 杭州医学院 基于vhl配体诱导bcr-abl蛋白降解的双功能分子及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1781639B1 (en) * 2004-07-28 2012-01-25 Janssen Pharmaceutica NV Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase

Also Published As

Publication number Publication date
PT2066327E (pt) 2013-02-06
NZ575030A (en) 2012-07-27
CN101516374B (zh) 2013-04-24
ME01514B (me) 2014-04-20
SG177219A1 (en) 2012-01-30
ZA200901818B (en) 2010-05-26
SI2066327T1 (sl) 2013-04-30
DK2066327T3 (da) 2013-02-11
CN101516374A (zh) 2009-08-26
ES2399670T3 (es) 2013-04-02
UA97249C2 (ru) 2012-01-25
BRPI0716992A2 (pt) 2013-09-17

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