RS50065B - Derivati benzofurana, njihova izrada i upotreba - Google Patents

Derivati benzofurana, njihova izrada i upotreba

Info

Publication number
RS50065B
RS50065B YUP-384/01A YU38401A RS50065B RS 50065 B RS50065 B RS 50065B YU 38401 A YU38401 A YU 38401A RS 50065 B RS50065 B RS 50065B
Authority
RS
Serbia
Prior art keywords
propyl
dihydroisobenzofuran
fluorophenyl
carbonitrile
indol
Prior art date
Application number
YUP-384/01A
Other languages
English (en)
Serbian (sr)
Inventor
Kim Andersen
Thomas Ruhland
Mario Rottlander
Klaus Peter Bogeso
Henrik Pedersen
Robert J.M. Dancer
Original Assignee
H. Lundbeck A/S.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S., filed Critical H. Lundbeck A/S.,
Publication of YU38401A publication Critical patent/YU38401A/sh
Publication of RS50065B publication Critical patent/RS50065B/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Indole Compounds (AREA)
YUP-384/01A 1998-12-08 1999-12-03 Derivati benzofurana, njihova izrada i upotreba RS50065B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11136098P 1998-12-08 1998-12-08
DKPA199801631 1998-12-09

Publications (2)

Publication Number Publication Date
YU38401A YU38401A (sh) 2005-06-10
RS50065B true RS50065B (sr) 2009-01-22

Family

ID=43768792

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-384/01A RS50065B (sr) 1998-12-08 1999-12-03 Derivati benzofurana, njihova izrada i upotreba

Country Status (18)

Country Link
EP (1) EP1137644B9 (cg-RX-API-DMAC7.html)
JP (1) JP2002531556A (cg-RX-API-DMAC7.html)
AR (1) AR021509A1 (cg-RX-API-DMAC7.html)
AT (1) ATE249451T1 (cg-RX-API-DMAC7.html)
AU (1) AU759248B2 (cg-RX-API-DMAC7.html)
CA (1) CA2353618A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ20012041A3 (cg-RX-API-DMAC7.html)
DE (1) DE69911243T2 (cg-RX-API-DMAC7.html)
DK (1) DK1137644T3 (cg-RX-API-DMAC7.html)
ES (1) ES2204175T3 (cg-RX-API-DMAC7.html)
HU (1) HUP0104510A3 (cg-RX-API-DMAC7.html)
IL (1) IL143082A (cg-RX-API-DMAC7.html)
ME (1) MEP38508A (cg-RX-API-DMAC7.html)
PT (1) PT1137644E (cg-RX-API-DMAC7.html)
RS (1) RS50065B (cg-RX-API-DMAC7.html)
SE (1) SE1137644T5 (cg-RX-API-DMAC7.html)
SI (1) SI1137644T1 (cg-RX-API-DMAC7.html)
WO (1) WO2000034263A1 (cg-RX-API-DMAC7.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR021155A1 (es) 1999-07-08 2002-06-12 Lundbeck & Co As H Tratamiento de desordenes neuroticos
EA008373B1 (ru) * 2000-07-07 2007-04-27 Х. Лундбекк А/С Применение эсциталопрама для лечения расстройства, связанного с посттравматическим стрессом
EA008372B1 (ru) * 2000-07-07 2007-04-27 Х.Лундбекк А/С Применение эсциталопрама для лечения расстройства, связанного с социальной тревогой
AU2001281740B2 (en) 2000-07-21 2006-02-16 H. Lundbeck A/S Novel compounds and their use as glycine transport inhibitors
AU2001288605A1 (en) * 2000-09-06 2002-03-22 Chugai Seiyaku Kabushiki Kaisha A traceless solid-phase synthesis of 2-imidazolones
US7235569B2 (en) 2003-05-02 2007-06-26 Wyeth Piperidinyl indole and tetrohydropyridinyl indole derivatives and method of their use
US7276603B2 (en) 2003-05-02 2007-10-02 Wyeth Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use
US8889730B2 (en) 2012-04-10 2014-11-18 Pfizer Inc. Indole and indazole compounds that activate AMPK
JP6064062B2 (ja) 2013-03-15 2017-01-18 ファイザー・インク Ampkを活性化させるインダゾール化合物
KR20240017363A (ko) * 2021-06-02 2024-02-07 세인트 조셉스 유니버시티 플루오린화 트립타민 화합물, 이의 유사체 및 이를 사용하는 방법
WO2025104490A1 (en) * 2023-11-14 2025-05-22 Mindset Pharma Inc. Indole derivatives as serotonergic agents useful for the treatment of disorders related thereto

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143703A (cg-RX-API-DMAC7.html) * 1965-03-18
GB1173312A (en) * 1966-03-17 1969-12-10 Kefalas As Heterocyclic Compounds
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
JP3773255B2 (ja) * 1993-12-28 2006-05-10 ファルマシア・アンド・アップジョン・カンパニー Cnsおよび心血管系疾患治療用複素環化合物
ZA954689B (en) * 1994-06-08 1996-01-29 Lundbeck & Co As H 4-Aryl-1-(indanmethyl dihydrobenzofuranmethyl or dihydrobenzothiophenemethyl) piperidines tetrahydropyridines or piperazines

Also Published As

Publication number Publication date
YU38401A (sh) 2005-06-10
SE1137644T5 (cg-RX-API-DMAC7.html) 2004-05-11
MEP38508A (en) 2011-02-10
EP1137644A1 (en) 2001-10-04
IL143082A0 (en) 2002-04-21
SE1137644T3 (cg-RX-API-DMAC7.html) 2003-12-02
ATE249451T1 (de) 2003-09-15
ES2204175T3 (es) 2004-04-16
EP1137644B1 (en) 2003-09-10
SI1137644T1 (en) 2003-12-31
IL143082A (en) 2004-06-20
CA2353618A1 (en) 2000-06-15
AU1503600A (en) 2000-06-26
CZ20012041A3 (cs) 2001-10-17
HUP0104510A3 (en) 2003-01-28
WO2000034263A1 (en) 2000-06-15
JP2002531556A (ja) 2002-09-24
DK1137644T3 (da) 2003-12-08
DE69911243D1 (de) 2003-10-16
AU759248B2 (en) 2003-04-10
HUP0104510A2 (hu) 2002-04-29
DE69911243T2 (de) 2004-07-15
AR021509A1 (es) 2002-07-24
PT1137644E (pt) 2004-01-30
EP1137644B9 (en) 2004-03-17

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