RS50065B - Derivati benzofurana, njihova izrada i upotreba - Google Patents

Derivati benzofurana, njihova izrada i upotreba

Info

Publication number
RS50065B
RS50065B YUP-384/01A YU38401A RS50065B RS 50065 B RS50065 B RS 50065B YU 38401 A YU38401 A YU 38401A RS 50065 B RS50065 B RS 50065B
Authority
RS
Serbia
Prior art keywords
propyl
dihydroisobenzofuran
fluorophenyl
carbonitrile
indol
Prior art date
Application number
YUP-384/01A
Other languages
English (en)
Serbian (sr)
Inventor
Kim Andersen
Thomas Ruhland
Mario Rottlander
Klaus Peter Bogeso
Henrik Pedersen
Robert J.M. Dancer
Original Assignee
H. Lundbeck A/S.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S., filed Critical H. Lundbeck A/S.,
Publication of YU38401A publication Critical patent/YU38401A/sh
Publication of RS50065B publication Critical patent/RS50065B/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Furan Compounds (AREA)
YUP-384/01A 1998-12-08 1999-12-03 Derivati benzofurana, njihova izrada i upotreba RS50065B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11136098P 1998-12-08 1998-12-08
DKPA199801631 1998-12-09

Publications (2)

Publication Number Publication Date
YU38401A YU38401A (sh) 2005-06-10
RS50065B true RS50065B (sr) 2009-01-22

Family

ID=43768792

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-384/01A RS50065B (sr) 1998-12-08 1999-12-03 Derivati benzofurana, njihova izrada i upotreba

Country Status (18)

Country Link
EP (1) EP1137644B9 (OSRAM)
JP (1) JP2002531556A (OSRAM)
AR (1) AR021509A1 (OSRAM)
AT (1) ATE249451T1 (OSRAM)
AU (1) AU759248B2 (OSRAM)
CA (1) CA2353618A1 (OSRAM)
CZ (1) CZ20012041A3 (OSRAM)
DE (1) DE69911243T2 (OSRAM)
DK (1) DK1137644T3 (OSRAM)
ES (1) ES2204175T3 (OSRAM)
HU (1) HUP0104510A3 (OSRAM)
IL (1) IL143082A (OSRAM)
ME (1) MEP38508A (OSRAM)
PT (1) PT1137644E (OSRAM)
RS (1) RS50065B (OSRAM)
SE (1) SE1137644T5 (OSRAM)
SI (1) SI1137644T1 (OSRAM)
WO (1) WO2000034263A1 (OSRAM)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR021155A1 (es) * 1999-07-08 2002-06-12 Lundbeck & Co As H Tratamiento de desordenes neuroticos
EA008373B1 (ru) * 2000-07-07 2007-04-27 Х. Лундбекк А/С Применение эсциталопрама для лечения расстройства, связанного с посттравматическим стрессом
EA008372B1 (ru) * 2000-07-07 2007-04-27 Х.Лундбекк А/С Применение эсциталопрама для лечения расстройства, связанного с социальной тревогой
EA005621B1 (ru) * 2000-07-21 2005-04-28 Х.Лундбекк А/С Гетероциклические соединения в качестве ингибиторов транспортера глицина
WO2002020493A2 (en) * 2000-09-06 2002-03-14 Chugai Seiyaku Kabushiki Kaisha A traceless solid-phase synthesis of 2-imidazolones
US7276603B2 (en) 2003-05-02 2007-10-02 Wyeth Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use
US7235569B2 (en) 2003-05-02 2007-06-26 Wyeth Piperidinyl indole and tetrohydropyridinyl indole derivatives and method of their use
US8889730B2 (en) 2012-04-10 2014-11-18 Pfizer Inc. Indole and indazole compounds that activate AMPK
CA2905242C (en) 2013-03-15 2016-11-29 Pfizer Inc. Indole compounds that activate ampk
AU2022287013A1 (en) * 2021-06-02 2023-12-07 Compass Pathfinder Ltd. Fluorinated tryptamine compounds, analogues thereof, and methods using same
WO2025104490A1 (en) * 2023-11-14 2025-05-22 Mindset Pharma Inc. Indole derivatives as serotonergic agents useful for the treatment of disorders related thereto

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (OSRAM) * 1965-03-18
GB1173312A (en) * 1966-03-17 1969-12-10 Kefalas As Heterocyclic Compounds
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
CA2176722A1 (en) * 1993-12-28 1995-07-06 Ruth E. Ten Brink Heterocyclic compounds for the treatment of cns and cardiovascular disorders
IL114026A (en) * 1994-06-08 1999-06-20 Lundbeck & Co As H 4-aryl-1-(indanmethyl dihydrobenzofuranmethyl or dihydrobenzo thiophenemethyl) piperidines tetrahydropyridines or piperazines and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
AR021509A1 (es) 2002-07-24
SE1137644T3 (OSRAM) 2003-12-02
DE69911243D1 (de) 2003-10-16
WO2000034263A1 (en) 2000-06-15
DK1137644T3 (da) 2003-12-08
ES2204175T3 (es) 2004-04-16
IL143082A0 (en) 2002-04-21
CA2353618A1 (en) 2000-06-15
JP2002531556A (ja) 2002-09-24
EP1137644A1 (en) 2001-10-04
IL143082A (en) 2004-06-20
EP1137644B9 (en) 2004-03-17
AU1503600A (en) 2000-06-26
SI1137644T1 (en) 2003-12-31
AU759248B2 (en) 2003-04-10
SE1137644T5 (OSRAM) 2004-05-11
PT1137644E (pt) 2004-01-30
EP1137644B1 (en) 2003-09-10
MEP38508A (en) 2011-02-10
CZ20012041A3 (cs) 2001-10-17
DE69911243T2 (de) 2004-07-15
HUP0104510A2 (hu) 2002-04-29
YU38401A (sh) 2005-06-10
HUP0104510A3 (en) 2003-01-28
ATE249451T1 (de) 2003-09-15

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