RO91516A - Procedeu pentru prepararea unor derivati de n-demetil-morfinan - Google Patents

Procedeu pentru prepararea unor derivati de n-demetil-morfinan

Info

Publication number
RO91516A
RO91516A RO85119568A RO11956885A RO91516A RO 91516 A RO91516 A RO 91516A RO 85119568 A RO85119568 A RO 85119568A RO 11956885 A RO11956885 A RO 11956885A RO 91516 A RO91516 A RO 91516A
Authority
RO
Romania
Prior art keywords
group
hydrogen atom
carbon atoms
benzoyloxy
acyloxy
Prior art date
Application number
RO85119568A
Other languages
English (en)
French (fr)
Other versions
RO91516B (ro
Inventor
Sandor Hosztafi
Tibor Timar
Julianna Nagy
Ilona Fabian
Original Assignee
Alkaloida Vegyeszeti Gyar Tiszavasvari,Hu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkaloida Vegyeszeti Gyar Tiszavasvari,Hu filed Critical Alkaloida Vegyeszeti Gyar Tiszavasvari,Hu
Publication of RO91516A publication Critical patent/RO91516A/ro
Publication of RO91516B publication Critical patent/RO91516B/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Stringed Musical Instruments (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Cephalosporin Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Finger-Pressure Massage (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Materials For Photolithography (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
RO119568A 1984-07-17 1985-07-15 Procedeu pentru prepararea unor derivati de n-demetil-morfinan RO91516B (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU842774A HU197750B (en) 1984-07-17 1984-07-17 Process for n-demethylation of morphine alkaloids

Publications (2)

Publication Number Publication Date
RO91516A true RO91516A (ro) 1987-06-30
RO91516B RO91516B (ro) 1987-07-01

Family

ID=10961043

Family Applications (1)

Application Number Title Priority Date Filing Date
RO119568A RO91516B (ro) 1984-07-17 1985-07-15 Procedeu pentru prepararea unor derivati de n-demetil-morfinan

Country Status (18)

Country Link
EP (1) EP0168686B1 (ro)
JP (1) JPS6193184A (ro)
AT (1) ATE41933T1 (ro)
BG (1) BG44029A3 (ro)
CS (1) CS251792B2 (ro)
DD (1) DD235639A5 (ro)
DE (1) DE3569244D1 (ro)
DK (1) DK322385A (ro)
ES (1) ES8603716A1 (ro)
FI (1) FI81583C (ro)
HU (1) HU197750B (ro)
IL (2) IL75509A0 (ro)
IN (1) IN166255B (ro)
NO (1) NO161915C (ro)
PL (1) PL254552A1 (ro)
RO (1) RO91516B (ro)
SU (1) SU1398776A3 (ro)
YU (1) YU45264B (ro)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5688974B2 (ja) * 2007-12-17 2015-03-25 マリンクロッド エルエルシー （＋）−オピエートの生成のためのプロセスおよび化合物
AU2008338970B2 (en) * 2007-12-17 2013-08-22 SpecGx LLC Sinomenine derivatives and processes for their synthesis
WO2010132570A1 (en) * 2009-05-12 2010-11-18 Board Of Regents The University Of Texas System Synthesis of morphine and related derivatives
PL2593095T3 (pl) * 2010-07-16 2019-12-31 Mallinckrodt Llc (+)-morfinany jako antagoniści receptora toll-podobnego 9 i ich terapeutyczne zastosowania
EP2753622B1 (en) 2011-09-08 2016-01-20 Mallinckrodt LLC Production of alkaloids without the isolation of intermediates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1584088A (ro) * 1967-08-04 1969-12-12
DE2254298A1 (de) * 1972-11-06 1974-05-16 Boehringer Sohn Ingelheim Neue (heteroarylmethyl)-normorphine, deren saeureadditionssalze, verfahren zu deren herstellung sowie deren verwendung als arzneimittel
DE2727805A1 (de) * 1977-06-21 1979-01-04 Goedecke Ag Verfahren zur herstellung von oxynormorphon

Also Published As

Publication number Publication date
ES8603716A1 (es) 1986-01-16
HU197750B (en) 1989-05-29
IL78503A (en) 1990-01-18
RO91516B (ro) 1987-07-01
YU45264B (en) 1992-05-28
EP0168686A1 (de) 1986-01-22
NO161915C (no) 1989-10-11
FI852779A0 (fi) 1985-07-15
IL75509A0 (en) 1985-10-31
NO161915B (no) 1989-07-03
DK322385A (da) 1986-01-18
DK322385D0 (da) 1985-07-15
DE3569244D1 (en) 1989-05-11
FI81583B (fi) 1990-07-31
FI852779L (fi) 1986-01-18
PL254552A1 (en) 1986-07-15
ATE41933T1 (de) 1989-04-15
HUT38645A (en) 1986-06-30
IN166255B (ro) 1990-03-31
JPS6193184A (ja) 1986-05-12
DD235639A5 (de) 1986-05-14
CS528085A2 (en) 1986-12-18
EP0168686B1 (de) 1989-04-05
YU117485A (en) 1988-04-30
BG44029A3 (en) 1988-09-15
FI81583C (fi) 1990-11-12
CS251792B2 (en) 1987-08-13
NO852838L (no) 1986-01-20
ES544385A0 (es) 1986-01-16
SU1398776A3 (ru) 1988-06-15

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