RO105699B1 - N-acil-derivati ai peptidglicanului monomer si procedeu pentru prepararea acestora - Google Patents

N-acil-derivati ai peptidglicanului monomer si procedeu pentru prepararea acestora

Info

Publication number
RO105699B1
RO105699B1 RO144579A RO14457990A RO105699B1 RO 105699 B1 RO105699 B1 RO 105699B1 RO 144579 A RO144579 A RO 144579A RO 14457990 A RO14457990 A RO 14457990A RO 105699 B1 RO105699 B1 RO 105699B1
Authority
RO
Romania
Prior art keywords
peptideglycane
derivates
acyl
monomer
preparation process
Prior art date
Application number
RO144579A
Other languages
English (en)
Inventor
Suskovic Bozidar
Naumski Radmila
Gomercic Vera
Mubrin Zdenko
Original Assignee
Pliva Pharm & Chem Works
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Pharm & Chem Works filed Critical Pliva Pharm & Chem Works
Publication of RO105699B1 publication Critical patent/RO105699B1/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
RO144579A 1989-03-27 1990-03-27 N-acil-derivati ai peptidglicanului monomer si procedeu pentru prepararea acestora RO105699B1 (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU00626/89A YU62689A (en) 1989-03-27 1989-03-27 N-acyl derivatives of peptidoglican monomer, their pharmaceutically acceptable salts, process for preparing thereof and their use as immunity modulators and immunoadjuvant

Publications (1)

Publication Number Publication Date
RO105699B1 true RO105699B1 (ro) 1992-11-30

Family

ID=25550749

Family Applications (1)

Application Number Title Priority Date Filing Date
RO144579A RO105699B1 (ro) 1989-03-27 1990-03-27 N-acil-derivati ai peptidglicanului monomer si procedeu pentru prepararea acestora

Country Status (12)

Country Link
US (1) US5153173A (ro)
EP (1) EP0390039A3 (ro)
JP (1) JPH04193898A (ro)
BG (1) BG51456A3 (ro)
CA (1) CA2013065A1 (ro)
CS (1) CS149090A2 (ro)
DD (1) DD296085A5 (ro)
HU (1) HU202546B (ro)
PL (1) PL162969B1 (ro)
RO (1) RO105699B1 (ro)
RU (1) RU1779258C (ro)
YU (1) YU62689A (ro)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69111401T2 (de) * 1990-12-21 1996-02-22 Pliva Pharm & Chem Works Tert-Butyloxycarbonyl-L-Tyrosyl-Peptidoglycanmonomer und deren 125 I-markiertes Derivat, deren Herstellung und Verwendung.
CA2115270A1 (en) * 1991-08-15 1993-03-04 Biserka Radosevic-Stasic The use of the peptidoglycan monomer (pgm), its n-acyl derivatives, and its metal complexes in the preparation of medicaments for the correction of the immunosuppressive and hepatosuppressive states of the organism
JP2002501931A (ja) * 1998-02-02 2002-01-22 プリンストン ユニバーシティ ＭｕｒＧの基質類似体、その製造方法およびそれを用いたアッセイ

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU40472B (en) * 1977-03-22 1986-02-28 Pliva Pharm & Chem Works Process for obtaining the basic repeated disaccharide-pentapeptide unit of peptidoglycane from the peptidoglycane complex generated in the submersion culturing of microorganisms
JPS58198496A (ja) * 1982-05-14 1983-11-18 Dainippon Pharmaceut Co Ltd グルコサミニルムラミルペプチド誘導体
SI8611982A8 (en) * 1986-11-19 1995-04-30 Pliva Pharm & Chem Works Process for preparing complexes of N-acethyl-glucosisaminyl-N-acethyl- muramoil-L-alanyl-D-izoglutaminyl-(L)-mezodiaminopimelyl-(D-amid)- (L)-alanyl-D-alanine

Also Published As

Publication number Publication date
YU62689A (en) 1991-02-28
CA2013065A1 (en) 1990-09-27
JPH04193898A (ja) 1992-07-13
HU202546B (en) 1991-03-28
RU1779258C (ru) 1992-11-30
HUT53661A (en) 1990-11-28
HU901831D0 (en) 1990-08-28
EP0390039A3 (en) 1991-11-13
EP0390039A2 (en) 1990-10-03
US5153173A (en) 1992-10-06
BG51456A3 (en) 1993-05-14
PL162969B1 (en) 1994-01-31
DD296085A5 (de) 1991-11-21
CS149090A2 (en) 1991-08-13

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