PT99502A - Processo para a preparacao de novos derivados de imidazol - Google Patents

Processo para a preparacao de novos derivados de imidazol

Info

Publication number
PT99502A
PT99502A PT99502A PT9950291A PT99502A PT 99502 A PT99502 A PT 99502A PT 99502 A PT99502 A PT 99502A PT 9950291 A PT9950291 A PT 9950291A PT 99502 A PT99502 A PT 99502A
Authority
PT
Portugal
Prior art keywords
group
branched
linear
preparation
imidazole derivatives
Prior art date
Application number
PT99502A
Other languages
English (en)
Other versions
PT99502B (pt
Inventor
Charles Malen
Guillaume De Nanteuil
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of PT99502A publication Critical patent/PT99502A/pt
Publication of PT99502B publication Critical patent/PT99502B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/16—Saturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/16—Saturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
    • C07C49/163—Saturated compounds containing keto groups bound to acyclic carbon atoms containing halogen containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/213—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/213—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C49/215—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/29—Saturated compounds containing keto groups bound to rings
    • C07C49/327—Saturated compounds containing keto groups bound to rings containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/38—Acyl halides
    • C07C53/46—Acyl halides containing halogen outside the carbonyl halide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/64—Acyl halides
    • C07C57/76—Acyl halides containing halogen outside the carbonyl halide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
PT99502A 1990-11-14 1991-11-13 Processo para a preparacao de novos derivados de imidazol PT99502B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9014086A FR2669030B1 (fr) 1990-11-14 1990-11-14 Nouveaux derives d'imidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Publications (2)

Publication Number Publication Date
PT99502A true PT99502A (pt) 1992-09-30
PT99502B PT99502B (pt) 1999-04-30

Family

ID=9402134

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99502A PT99502B (pt) 1990-11-14 1991-11-13 Processo para a preparacao de novos derivados de imidazol

Country Status (15)

Country Link
US (1) US5173502A (pt)
EP (1) EP0486385B1 (pt)
JP (1) JPH0710851B2 (pt)
AT (1) ATE116304T1 (pt)
AU (1) AU639154B2 (pt)
CA (1) CA2055325A1 (pt)
DE (1) DE69106323T2 (pt)
DK (1) DK0486385T3 (pt)
ES (1) ES2069249T3 (pt)
FR (1) FR2669030B1 (pt)
GR (1) GR3015209T3 (pt)
IE (1) IE66161B1 (pt)
NZ (1) NZ240578A (pt)
PT (1) PT99502B (pt)
ZA (1) ZA918991B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698789B1 (fr) * 1992-12-07 1995-03-03 Pf Medicament Utilisation de l'idazoxan et ses dérivés pour la préparation d'un médicament destiné au traitement de la maladie de Parkinson et de son évolution.
FR2706303B1 (fr) * 1993-06-18 1995-09-08 Pf Medicament Utilisation de l'Efaroxan et de ses dérivés pour la préparation d'un médicament destiné au traitement de la maladie de Parkinson.
FR2707166B1 (fr) * 1993-07-09 1995-09-29 Pf Medicament Utilisation de l'efaroxan et de ses dérivés pour la fabrication de médicaments destinés au traitement de maladies neurodégénératives et leur progression .
US6448282B1 (en) 1995-05-30 2002-09-10 Gliatech, Inc. 1H-4(5)-substituted imidazole derivatives
ES2170859T3 (es) * 1995-05-30 2002-08-16 Gliatech Inc Derivados de imidazol 1h-4(5)-sustituidos.
KR100432577B1 (ko) * 2002-02-08 2004-05-24 주식회사유한양행 이미다졸 유도체의 제조방법
US8188126B2 (en) * 2002-05-16 2012-05-29 Pierre Fabre Medicament Imidazolic compounds and use thereof as alpha-2 adrenergic receptors
US20080146523A1 (en) * 2006-12-18 2008-06-19 Guido Galley Imidazole derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4497818A (en) * 1980-09-10 1985-02-05 Syntex (U.S.A.) Inc. 2-(1,4-Benzodioxan-2-ylalkyl)imidazoles useful as antihypertensives and platelet aggregation inhibitors
US4576958A (en) * 1984-01-23 1986-03-18 E. I. Du Pont De Nemours And Company Antihypertensive 4,5-diaryl-1H-imidazole-2-methanol derivatives
FI81092C (fi) * 1986-05-15 1990-09-10 Farmos Oy Foerfarande foer framstaellning av terapeutiskt aktiva 4(5)-(2,3-dihydro-1h-inden-2-yl)-imidazolderivat.
JPH02115145A (ja) * 1988-10-26 1990-04-27 Canon Inc 液晶性化合物、それを含有する液晶組成物および液晶素子

Also Published As

Publication number Publication date
EP0486385B1 (fr) 1994-12-28
IE66161B1 (en) 1995-12-13
JPH04266875A (ja) 1992-09-22
ES2069249T3 (es) 1995-05-01
PT99502B (pt) 1999-04-30
EP0486385A1 (fr) 1992-05-20
ZA918991B (en) 1992-08-26
DK0486385T3 (da) 1995-06-12
DE69106323D1 (de) 1995-02-09
CA2055325A1 (fr) 1992-05-15
FR2669030B1 (fr) 1992-12-31
IE913964A1 (en) 1992-05-20
ATE116304T1 (de) 1995-01-15
JPH0710851B2 (ja) 1995-02-08
NZ240578A (en) 1992-12-23
GR3015209T3 (en) 1995-05-31
FR2669030A1 (fr) 1992-05-15
AU8777991A (en) 1992-05-21
AU639154B2 (en) 1993-07-15
US5173502A (en) 1992-12-22
DE69106323T2 (de) 1995-06-22

Similar Documents

Publication Publication Date Title
DE69100079D1 (de) Naphthalin-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
PT97710A (pt) Processo para a preparacao de novos derivados da amino-piperidina,da amino-pirrolidina e de amino-per-hidroazepina
ATE124047T1 (de) Oxazolopyridinderivate, verfahren zu ihrer herstellung und die sie enthaltenden pharmazeutischen zusammensetzungen.
DE3677452D1 (de) Chinazolinderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ES535552A0 (es) Un procedimiento para la preparacion de nuevos derivados de tiazolidina.
ES539658A0 (es) Procedimiento de preparacion de nuevos derivados de la xan- tina y de sus sales de adicion con acidos apropiados
ATE254612T1 (de) Zuckerderivate, geliermittel, geliermittelzubereitungen, verfahren zu ihrer herstellung und gelzubereitungen
DE3777852D1 (de) Dekahydrochinolinderivate, verfahren zu ihrer herstellung, zwischenprodukte zu ihrer herstellung, ihre verwendung als arzneimittel und diese enthaltende zubereitungen.
PT83277B (pt) Processo para a preparacao de carboxi-tiadiazois, -oxadiazois, -triazois, -tiadiazinas, -oxidiazinas e -triazinas, substituidos
PT99502A (pt) Processo para a preparacao de novos derivados de imidazol
PT99644A (pt) Processo para a preparacao de novos derivados de guanidina
SE8406302L (sv) Nya aminoguanidinderivat och ett forfarande for deras framstellning
DK400781A (da) Fremgangsmaade til fremstilling af 2-(1,4-benzodioxan-2-ylalkyl) imidazoler
NO177995C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive 1,3-dioksanderivater
NO852514L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 8-alkyltio-2-piperazino-pyrimido (5,4-d) pyrimidin-derivater.
ES529069A0 (es) Procedimiento de preparar nuevos derivados de sales inertes de hidroxido de aminopiridinio y sus sales correspondientes
ATE179972T1 (de) Pyridazinone-derivate und verfahren zur deren herstellung
DE68902946T2 (de) Heteroarotinoid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.
ES2032985T3 (es) Nuevos tripeptidos de estructura policiclica nitrogenada, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
BR8305266A (pt) Composto ativo como fungicida e processo de preparacao; composicao fungicida e metodo para combater os fungos num determinado local
PT78717A (de) Neue 1-acetonyl-2-(phenylimino)-imidazolidine deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
ATE20588T1 (de) Heterozyklische verbindungen geeignet als pestizide und verfahren zu ihrer herstellung.
ATE53839T1 (de) 2,3-dihydro-3-phenyl-benzofuran-2-onacetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920525

FG3A Patent granted, date of granting

Effective date: 19990126

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20000731