PT984936E - Cianoguanidinas como inibidores da proliferacao celular - Google Patents
Cianoguanidinas como inibidores da proliferacao celularInfo
- Publication number
- PT984936E PT984936E PT98924052T PT98924052T PT984936E PT 984936 E PT984936 E PT 984936E PT 98924052 T PT98924052 T PT 98924052T PT 98924052 T PT98924052 T PT 98924052T PT 984936 E PT984936 E PT 984936E
- Authority
- PT
- Portugal
- Prior art keywords
- stands
- alkoxycarbonyl
- carboxy
- alkoxy
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9711123.1A GB9711123D0 (en) | 1997-05-29 | 1997-05-29 | Novel cyanoguanidines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT984936E true PT984936E (pt) | 2004-02-27 |
Family
ID=10813253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98924052T PT984936E (pt) | 1997-05-29 | 1998-05-15 | Cianoguanidinas como inibidores da proliferacao celular |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US6346520B1 (pt) |
| EP (1) | EP0984936B1 (pt) |
| JP (1) | JP4349476B2 (pt) |
| KR (1) | KR100549631B1 (pt) |
| CN (1) | CN1121389C (pt) |
| AT (1) | ATE248819T1 (pt) |
| AU (1) | AU733000B2 (pt) |
| CA (1) | CA2292775C (pt) |
| CZ (1) | CZ293275B6 (pt) |
| DE (1) | DE69817810T2 (pt) |
| DK (1) | DK0984936T3 (pt) |
| ES (1) | ES2206931T3 (pt) |
| GB (1) | GB9711123D0 (pt) |
| HK (1) | HK1027568A1 (pt) |
| HU (1) | HUP0003823A3 (pt) |
| NZ (1) | NZ501266A (pt) |
| PL (1) | PL190249B1 (pt) |
| PT (1) | PT984936E (pt) |
| RO (1) | RO119880B1 (pt) |
| RU (1) | RU2194697C2 (pt) |
| WO (1) | WO1998054141A1 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000061561A1 (en) | 1999-04-09 | 2000-10-19 | Shionogi Bioresearch Corp. | Cyanoguanidine compounds |
| AU1494702A (en) | 2000-11-21 | 2002-06-03 | Leo Pharma As | Cyanoguanidine prodrugs |
| US20030045515A1 (en) * | 2001-05-24 | 2003-03-06 | Lise Binderup | Combination medicament for treatment of neoplastic diseases |
| IL158574A0 (en) | 2001-05-24 | 2004-05-12 | Leo Pharma As | Novel pyridyl cyanoguanidine compounds |
| US7253193B2 (en) | 2002-05-17 | 2007-08-07 | Leo Pharma A/S | Cyanoguanidine prodrugs |
| EP1838696B1 (en) | 2004-12-22 | 2016-03-09 | Leo Pharma A/S | Novel cyanoguanidine compounds |
| WO2009072004A2 (en) | 2007-09-26 | 2009-06-11 | Gemin X Pharmaceuticals Canada, Inc. | Compositions and methods for effecting nad+ levels using a nicotinamide phosphoribosyl transferase inhibitor |
| US8173677B2 (en) | 2007-09-26 | 2012-05-08 | Gemin X Pharmaceuticals Canada Inc. | Compositions and methods for effecting NAD+ levels using a nicotinamide phosphoribosyl transferase inhibitor |
| WO2010088842A1 (zh) * | 2009-02-06 | 2010-08-12 | 天津和美生物技术有限公司 | 含有吡啶基氰基胍的药物组合物及其制备和应用 |
| US8912184B1 (en) | 2010-03-01 | 2014-12-16 | Alzheimer's Institute Of America, Inc. | Therapeutic and diagnostic methods |
| EP2634173A4 (en) | 2010-10-26 | 2014-04-02 | Tianjin Hemay Bio Tech Co Ltd | POLYMORPH OF N- (6- (4-CHLOROPHENOXY) HEXYL-) N'-CYANO-N '' - (4-PYRIDYL-) GUANIDINE, PREPARATION THEREOF AND USE THEREOF |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9219472D0 (en) * | 1992-09-15 | 1992-10-28 | Leo Pharm Prod Ltd | Chemical compounds |
| GB9711125D0 (en) * | 1997-05-29 | 1997-07-23 | Leo Pharm Prod Ltd | Novel cyanoguanidines |
| AU1494702A (en) * | 2000-11-21 | 2002-06-03 | Leo Pharma As | Cyanoguanidine prodrugs |
-
1997
- 1997-05-29 GB GBGB9711123.1A patent/GB9711123D0/en active Pending
-
1998
- 1998-05-15 WO PCT/DK1998/000193 patent/WO1998054141A1/en not_active Application Discontinuation
- 1998-05-15 KR KR1019997011148A patent/KR100549631B1/ko not_active IP Right Cessation
- 1998-05-15 CN CN98805591A patent/CN1121389C/zh not_active Expired - Lifetime
- 1998-05-15 PL PL98337059A patent/PL190249B1/pl not_active IP Right Cessation
- 1998-05-15 DK DK98924052T patent/DK0984936T3/da active
- 1998-05-15 RO RO99-01253A patent/RO119880B1/ro unknown
- 1998-05-15 CA CA002292775A patent/CA2292775C/en not_active Expired - Lifetime
- 1998-05-15 US US09/424,631 patent/US6346520B1/en not_active Expired - Lifetime
- 1998-05-15 RU RU99128101/04A patent/RU2194697C2/ru active
- 1998-05-15 HU HU0003823A patent/HUP0003823A3/hu unknown
- 1998-05-15 JP JP50011199A patent/JP4349476B2/ja not_active Expired - Lifetime
- 1998-05-15 AT AT98924052T patent/ATE248819T1/de not_active IP Right Cessation
- 1998-05-15 DE DE69817810T patent/DE69817810T2/de not_active Expired - Lifetime
- 1998-05-15 AU AU76383/98A patent/AU733000B2/en not_active Expired
- 1998-05-15 CZ CZ19994240A patent/CZ293275B6/cs not_active IP Right Cessation
- 1998-05-15 ES ES98924052T patent/ES2206931T3/es not_active Expired - Lifetime
- 1998-05-15 EP EP98924052A patent/EP0984936B1/en not_active Expired - Lifetime
- 1998-05-15 NZ NZ501266A patent/NZ501266A/en not_active IP Right Cessation
- 1998-05-15 PT PT98924052T patent/PT984936E/pt unknown
-
2000
- 2000-10-23 HK HK00106694A patent/HK1027568A1/xx not_active IP Right Cessation
-
2002
- 2002-02-04 US US10/061,204 patent/US6646129B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998054141A1 (en) | 1998-12-03 |
| PL190249B1 (pl) | 2005-11-30 |
| HUP0003823A2 (en) | 2001-03-28 |
| AU7638398A (en) | 1998-12-30 |
| GB9711123D0 (en) | 1997-07-23 |
| AU733000B2 (en) | 2001-05-03 |
| ATE248819T1 (de) | 2003-09-15 |
| RU2194697C2 (ru) | 2002-12-20 |
| CZ293275B6 (cs) | 2004-03-17 |
| US6346520B1 (en) | 2002-02-12 |
| US20020107400A1 (en) | 2002-08-08 |
| DE69817810T2 (de) | 2004-07-01 |
| CA2292775A1 (en) | 1998-12-03 |
| NZ501266A (en) | 2001-09-28 |
| CN1258277A (zh) | 2000-06-28 |
| EP0984936A1 (en) | 2000-03-15 |
| HUP0003823A3 (en) | 2001-09-28 |
| JP2001526692A (ja) | 2001-12-18 |
| EP0984936B1 (en) | 2003-09-03 |
| DK0984936T3 (da) | 2004-01-05 |
| CZ9904240A3 (cs) | 2001-01-17 |
| DE69817810D1 (de) | 2003-10-09 |
| CA2292775C (en) | 2009-10-13 |
| ES2206931T3 (es) | 2004-05-16 |
| KR20010013164A (ko) | 2001-02-26 |
| HK1027568A1 (en) | 2001-01-19 |
| PL337059A1 (en) | 2000-07-31 |
| JP4349476B2 (ja) | 2009-10-21 |
| US6646129B2 (en) | 2003-11-11 |
| RO119880B1 (ro) | 2005-05-30 |
| KR100549631B1 (ko) | 2006-02-08 |
| CN1121389C (zh) | 2003-09-17 |
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