PT951471E - Inibidores cicloalquilo de farnesiltransferase de proteinas - Google Patents
Inibidores cicloalquilo de farnesiltransferase de proteinasInfo
- Publication number
- PT951471E PT951471E PT97954575T PT97954575T PT951471E PT 951471 E PT951471 E PT 951471E PT 97954575 T PT97954575 T PT 97954575T PT 97954575 T PT97954575 T PT 97954575T PT 951471 E PT951471 E PT 951471E
- Authority
- PT
- Portugal
- Prior art keywords
- protein
- inhibitors
- farnesiltransferase
- cicloalquilo
- endometriosis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06147—Dipeptides with the first amino acid being heterocyclic and His-amino acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3366196P | 1996-12-17 | 1996-12-17 | |
| US5683197P | 1997-08-22 | 1997-08-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT951471E true PT951471E (pt) | 2004-08-31 |
Family
ID=26709973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97954575T PT951471E (pt) | 1996-12-17 | 1997-12-16 | Inibidores cicloalquilo de farnesiltransferase de proteinas |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6281194B1 (pt) |
| EP (1) | EP0951471B1 (pt) |
| JP (1) | JP2001506265A (pt) |
| KR (1) | KR20000057601A (pt) |
| AT (1) | ATE261987T1 (pt) |
| AU (1) | AU721786C (pt) |
| BR (1) | BR9713744A (pt) |
| CA (1) | CA2264207A1 (pt) |
| CO (1) | CO4920227A1 (pt) |
| DE (1) | DE69728165T2 (pt) |
| DK (1) | DK0951471T3 (pt) |
| ES (1) | ES2216189T3 (pt) |
| HR (1) | HRP970693B1 (pt) |
| ID (1) | ID19142A (pt) |
| IL (1) | IL128546A0 (pt) |
| NO (1) | NO992933D0 (pt) |
| NZ (1) | NZ334702A (pt) |
| PE (1) | PE46999A1 (pt) |
| PT (1) | PT951471E (pt) |
| TW (1) | TW552259B (pt) |
| WO (1) | WO1998027109A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE261987T1 (de) | 1996-12-17 | 2004-04-15 | Warner Lambert Co | Cycloalkyl inhibitoren der protein- farnesyltransferase |
| JP2002513031A (ja) | 1998-04-27 | 2002-05-08 | ワーナー−ランバート・カンパニー | ファルネシルトランスフェラーゼ阻害剤としての機能化されたアルキルおよびアルケニル側鎖を有するグリシンアミド誘導体 |
| US6455734B1 (en) * | 2000-08-09 | 2002-09-24 | Magnesium Diagnostics, Inc. | Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states |
| DE60234354D1 (de) * | 2001-08-24 | 2009-12-24 | Univ Yale | Piperazinon-verbindungen als antitumorale und krebsbekämpfende mittel |
| AU2007229363B2 (en) * | 2001-08-24 | 2009-06-04 | University Of South Florida | Piperazinone Compounds as Anti-Tumor and Anti-Cancer Agents and the Methods of Treatment |
| WO2005049589A2 (en) * | 2003-10-14 | 2005-06-02 | Cadila Healthcare Limited | Heterocyclic compounds for the treatment of hyperlipidemia, diabetes, obesity and similar diseases |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU681454B2 (en) * | 1993-11-05 | 1997-08-28 | Warner-Lambert Company | Substituted DI- and tripeptide inhibitors of protein:farnesyl transferase |
| US5571792A (en) | 1994-06-30 | 1996-11-05 | Warner-Lambert Company | Histidine and homohistidine derivatives as inhibitors of protein farnesyltransferase |
| ATE261987T1 (de) | 1996-12-17 | 2004-04-15 | Warner Lambert Co | Cycloalkyl inhibitoren der protein- farnesyltransferase |
-
1997
- 1997-12-16 AT AT97954575T patent/ATE261987T1/de not_active IP Right Cessation
- 1997-12-16 IL IL12854697A patent/IL128546A0/xx unknown
- 1997-12-16 WO PCT/US1997/023280 patent/WO1998027109A1/en not_active Application Discontinuation
- 1997-12-16 US US09/319,422 patent/US6281194B1/en not_active Expired - Fee Related
- 1997-12-16 DE DE69728165T patent/DE69728165T2/de not_active Expired - Fee Related
- 1997-12-16 JP JP52794298A patent/JP2001506265A/ja not_active Abandoned
- 1997-12-16 BR BR9713744A patent/BR9713744A/pt not_active Application Discontinuation
- 1997-12-16 KR KR1019990705384A patent/KR20000057601A/ko not_active Application Discontinuation
- 1997-12-16 PE PE1997001119A patent/PE46999A1/es not_active Application Discontinuation
- 1997-12-16 PT PT97954575T patent/PT951471E/pt unknown
- 1997-12-16 DK DK97954575T patent/DK0951471T3/da active
- 1997-12-16 CA CA002264207A patent/CA2264207A1/en not_active Abandoned
- 1997-12-16 NZ NZ334702A patent/NZ334702A/xx unknown
- 1997-12-16 CO CO97073366A patent/CO4920227A1/es unknown
- 1997-12-16 ES ES97954575T patent/ES2216189T3/es not_active Expired - Lifetime
- 1997-12-16 AU AU58990/98A patent/AU721786C/en not_active Ceased
- 1997-12-16 EP EP97954575A patent/EP0951471B1/en not_active Expired - Lifetime
- 1997-12-17 HR HR970693A patent/HRP970693B1/xx not_active IP Right Cessation
- 1997-12-17 ID IDP973902A patent/ID19142A/id unknown
-
1998
- 1998-05-26 TW TW086119079A patent/TW552259B/zh active
-
1999
- 1999-06-16 NO NO992933A patent/NO992933D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL128546A0 (en) | 2000-01-31 |
| JP2001506265A (ja) | 2001-05-15 |
| DK0951471T3 (da) | 2004-07-19 |
| NO992933L (no) | 1999-06-16 |
| TW552259B (en) | 2003-09-11 |
| BR9713744A (pt) | 2000-03-21 |
| PE46999A1 (es) | 1999-05-20 |
| HRP970693A2 (en) | 1998-10-31 |
| HRP970693B1 (en) | 2002-06-30 |
| AU721786C (en) | 2001-08-02 |
| DE69728165T2 (de) | 2005-01-20 |
| ES2216189T3 (es) | 2004-10-16 |
| EP0951471A1 (en) | 1999-10-27 |
| WO1998027109A1 (en) | 1998-06-25 |
| AU5899098A (en) | 1998-07-15 |
| CO4920227A1 (es) | 2000-05-29 |
| EP0951471B1 (en) | 2004-03-17 |
| CA2264207A1 (en) | 1998-06-25 |
| US6281194B1 (en) | 2001-08-28 |
| NZ334702A (en) | 2000-11-24 |
| NO992933D0 (no) | 1999-06-16 |
| KR20000057601A (ko) | 2000-09-25 |
| ID19142A (id) | 1998-06-18 |
| DE69728165D1 (de) | 2004-04-22 |
| ATE261987T1 (de) | 2004-04-15 |
| AU721786B2 (en) | 2000-07-13 |
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