PT944396E - Composicoes e processos para melhorar o funcionamento gastrointestinal - Google Patents
Composicoes e processos para melhorar o funcionamento gastrointestinalInfo
- Publication number
- PT944396E PT944396E PT97946986T PT97946986T PT944396E PT 944396 E PT944396 E PT 944396E PT 97946986 T PT97946986 T PT 97946986T PT 97946986 T PT97946986 T PT 97946986T PT 944396 E PT944396 E PT 944396E
- Authority
- PT
- Portugal
- Prior art keywords
- glp
- compositions
- processes
- improving gastrointestinal
- growth
- Prior art date
Links
- 230000002496 gastric effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 102400000326 Glucagon-like peptide 2 Human genes 0.000 abstract 3
- 101800000221 Glucagon-like peptide 2 Proteins 0.000 abstract 3
- TWSALRJGPBVBQU-PKQQPRCHSA-N glucagon-like peptide 2 Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(O)=O)[C@@H](C)CC)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)CC)C1=CC=CC=C1 TWSALRJGPBVBQU-PKQQPRCHSA-N 0.000 abstract 3
- 239000000813 peptide hormone Substances 0.000 abstract 3
- 210000002429 large intestine Anatomy 0.000 abstract 2
- 210000000813 small intestine Anatomy 0.000 abstract 2
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 235000016709 nutrition Nutrition 0.000 abstract 1
- 208000030212 nutrition disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/763,177 US5952301A (en) | 1996-12-10 | 1996-12-10 | Compositions and methods for enhancing intestinal function |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT944396E true PT944396E (pt) | 2003-07-31 |
Family
ID=25067085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97946986T PT944396E (pt) | 1996-12-10 | 1997-12-10 | Composicoes e processos para melhorar o funcionamento gastrointestinal |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5952301A (pt) |
| EP (1) | EP0944396B1 (pt) |
| AT (1) | ATE233096T1 (pt) |
| AU (1) | AU5220098A (pt) |
| CA (1) | CA2274596C (pt) |
| DE (1) | DE69719360T2 (pt) |
| DK (1) | DK0944396T3 (pt) |
| ES (1) | ES2193406T3 (pt) |
| PT (1) | PT944396E (pt) |
| WO (1) | WO1998025644A1 (pt) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020025933A1 (en) * | 1996-08-30 | 2002-02-28 | Knudsen Liselotte Bjerre | GLP-2 derivatives |
| CA2236519C (en) | 1997-05-02 | 2011-09-13 | 1149336 Ontario Inc. | Methods of enhancing functioning of the large intestine |
| PT981362E (pt) * | 1997-05-16 | 2004-03-31 | Ontario Inc 1149336 | Metodos de melhoramento do funcionamento do tracto gastrointestinal superior |
| ES2288807T1 (es) | 1998-02-02 | 2008-02-01 | Trustees Of Tufts College | Uso de inhibidores de dipeptidasa para regular el metabolismo de la glucosa. |
| WO1999058144A1 (en) * | 1998-05-11 | 1999-11-18 | 1149336 Ontario Inc. | Methods of enhancing functioning of the large intestine |
| US6979697B1 (en) | 1998-08-21 | 2005-12-27 | Point Therapeutics, Inc. | Regulation of substrate activity |
| IL141471A0 (en) * | 1998-08-21 | 2002-03-10 | Point Therapeutics Inc | Regulation of substrate activity |
| GB9906714D0 (en) | 1999-03-23 | 1999-05-19 | Ferring Bv | Compositions for improving fertility |
| GB9906715D0 (en) | 1999-03-23 | 1999-05-19 | Ferring Bv | Compositions for promoting growth |
| EP1806138A1 (en) * | 1999-05-25 | 2007-07-11 | Point Therapeutics, Inc. | Anti-tumor agents comprising boroproline compounds |
| AU781897B2 (en) * | 1999-05-25 | 2005-06-23 | Point Therapeutics, Inc. | Anti-tumor comprising boroproline compounds |
| US6890904B1 (en) | 1999-05-25 | 2005-05-10 | Point Therapeutics, Inc. | Anti-tumor agents |
| JP2003534237A (ja) * | 1999-11-03 | 2003-11-18 | ノボ ノルディスク アクティーゼルスカブ | 食欲の抑制又は満腹の惹起のための成長ホルモン又は成長ホルモン分泌促進物質の使用 |
| US6599882B1 (en) | 1999-11-05 | 2003-07-29 | Joseph A. Rogoff | Secretin and secretin pharmaceuticals for treating lactose intolerance |
| GB9930882D0 (en) * | 1999-12-30 | 2000-02-23 | Nps Allelix Corp | GLP-2 formulations |
| ATE396738T1 (de) | 2000-09-18 | 2008-06-15 | Sanos Bioscience As | Verwendung von glp-2-peptiden |
| US20070135345A1 (en) * | 2000-09-18 | 2007-06-14 | Henriksen Dennis B | Use of GLP-2 for the treatment or prevention, of bone-related disorders |
| US7371721B2 (en) * | 2000-09-18 | 2008-05-13 | Sanos Bioscience A/S | Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes |
| US20080249016A1 (en) * | 2000-09-18 | 2008-10-09 | Sanos Bioscience A/S | Use of GLP-2 in a combination treatment for bone-related disorders |
| JP4280070B2 (ja) * | 2001-02-16 | 2009-06-17 | コンジュケム バイオテクノロジーズ インコーポレイテッド | 胃腸疾患および胃腸障害の処置のための長期持続性グルカゴン様ペプチド２（ｇｌｐ−２） |
| US7727964B2 (en) * | 2001-11-26 | 2010-06-01 | Trustees Of Tufts College | Peptidomimetic inhibitors of post-proline cleaving enzymes |
| AU2002360453C1 (en) * | 2001-11-26 | 2009-06-18 | The Brigham And Women's Hospital, Inc. | Methods for treating autoimmune disorders, and reagents related thereto |
| US20040038864A1 (en) * | 2002-06-27 | 2004-02-26 | Per Balschmidt | Use of dimethyl sulfone as isotonicity agent |
| US7411039B2 (en) * | 2002-10-14 | 2008-08-12 | Novo Nordisk A/S | GLP-2 compounds, formulations, and uses thereof |
| US20050026859A1 (en) * | 2002-11-12 | 2005-02-03 | John Hilfinger | Methods and compositions of gene delivery agents for systemic and local therapy |
| US20080026077A1 (en) * | 2002-11-12 | 2008-01-31 | John Hilfinger | Methods and compositions of gene delivery agents for systemic and local therapy |
| US7317109B2 (en) * | 2003-11-12 | 2008-01-08 | Phenomix Corporation | Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| BRPI0416444B8 (pt) * | 2003-11-12 | 2021-05-25 | Chiesi Farm Spa | composto de ácido borônico heterocíclico, composição farmacêutica, e, combinação farmacêutica compreendendo o mesmo |
| US7576121B2 (en) * | 2003-11-12 | 2009-08-18 | Phenomix Corporation | Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| US7767828B2 (en) * | 2003-11-12 | 2010-08-03 | Phenomix Corporation | Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| US20080269311A1 (en) * | 2004-07-14 | 2008-10-30 | Edwin Bernard Villhauer | Combination of Dpp-Iv Inhibitors and Compounds Modulating 5-Ht3 and/or 5-Ht4 Receptors |
| EA014184B1 (ru) | 2005-05-04 | 2010-10-29 | Зеаланд Фарма А/С | Аналоги глюкагонподобного пептида-2 (glp-2) |
| US7825139B2 (en) * | 2005-05-25 | 2010-11-02 | Forest Laboratories Holdings Limited (BM) | Compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| CN101573376B (zh) | 2006-11-08 | 2013-11-06 | 西兰制药公司 | 选择性胰高血糖素样肽-2（glp-2）类似物 |
| US20110295151A1 (en) * | 2010-05-26 | 2011-12-01 | Bakos Gregory J | Enteroendocrine Manipulation for Metabolic Effect |
| EA028929B1 (ru) | 2012-05-03 | 2018-01-31 | Зилэнд Фарма А/С | Аналоги глюкагоноподобного пептида-2 (glp-2) |
| WO2015006228A1 (en) | 2013-07-08 | 2015-01-15 | The University Of Utah Research Foundation | Methods for treatment of and prophylaxis against inflammatory disorders |
| EP3299023A4 (en) * | 2015-05-21 | 2019-03-20 | Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences | MESENCHYMAL SUBSTITUTE CELL CULTIVATED IN HYPOXIA AND USE THEREOF |
| CN106589110B (zh) * | 2015-10-15 | 2020-01-17 | 上海迈迹生物医药科技有限公司 | 包含聚合物和glp-2衍生物的缀合物 |
| CN117384274A (zh) | 2016-12-09 | 2024-01-12 | 西兰制药公司 | 酰化的glp-1/glp-2双重激动剂 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993006839A1 (en) * | 1991-10-07 | 1993-04-15 | Brigham And Women's Hospital | Method for enhancing gut absorption |
| NZ243071A (en) * | 1992-06-08 | 1994-09-27 | Kabi Pharmacia Ab | Igf-2 (or analogue) compositions for pharmaceutical uses |
| US5990077A (en) * | 1995-04-14 | 1999-11-23 | 1149336 Ontario Inc. | Glucagon-like peptide-2 and its therapeutic use |
| ATE227309T1 (de) * | 1996-04-12 | 2002-11-15 | Ontario Inc 1149336 | Analoge des glucagon ähnlichen peptides -2 |
-
1996
- 1996-12-10 US US08/763,177 patent/US5952301A/en not_active Expired - Lifetime
-
1997
- 1997-12-10 PT PT97946986T patent/PT944396E/pt unknown
- 1997-12-10 AT AT97946986T patent/ATE233096T1/de active
- 1997-12-10 DK DK97946986T patent/DK0944396T3/da active
- 1997-12-10 WO PCT/CA1997/000945 patent/WO1998025644A1/en active IP Right Grant
- 1997-12-10 EP EP97946986A patent/EP0944396B1/en not_active Expired - Lifetime
- 1997-12-10 ES ES97946986T patent/ES2193406T3/es not_active Expired - Lifetime
- 1997-12-10 DE DE69719360T patent/DE69719360T2/de not_active Expired - Lifetime
- 1997-12-10 AU AU52200/98A patent/AU5220098A/en not_active Abandoned
- 1997-12-10 CA CA002274596A patent/CA2274596C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE233096T1 (de) | 2003-03-15 |
| EP0944396A1 (en) | 1999-09-29 |
| DE69719360T2 (de) | 2003-12-04 |
| WO1998025644A1 (en) | 1998-06-18 |
| CA2274596C (en) | 2004-11-09 |
| DK0944396T3 (da) | 2003-06-23 |
| AU5220098A (en) | 1998-07-03 |
| ES2193406T3 (es) | 2003-11-01 |
| US5952301A (en) | 1999-09-14 |
| DE69719360D1 (de) | 2003-04-03 |
| EP0944396B1 (en) | 2003-02-26 |
| CA2274596A1 (en) | 1998-06-18 |
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