PT912515E - Piperidinas 1,4-di-substituidas como antagonistas muscarinicos - Google Patents
Piperidinas 1,4-di-substituidas como antagonistas muscarinicosInfo
- Publication number
- PT912515E PT912515E PT97932321T PT97932321T PT912515E PT 912515 E PT912515 E PT 912515E PT 97932321 T PT97932321 T PT 97932321T PT 97932321 T PT97932321 T PT 97932321T PT 912515 E PT912515 E PT 912515E
- Authority
- PT
- Portugal
- Prior art keywords
- alkyl
- cycloalkyl
- heteroaryl
- aryl
- alkylheteroaryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67861896A | 1996-07-10 | 1996-07-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT912515E true PT912515E (pt) | 2003-03-31 |
Family
ID=24723553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97932321T PT912515E (pt) | 1996-07-10 | 1997-07-08 | Piperidinas 1,4-di-substituidas como antagonistas muscarinicos |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0912515B1 (pt) |
| JP (1) | JP3068206B2 (pt) |
| KR (1) | KR20000023599A (pt) |
| AT (1) | ATE227708T1 (pt) |
| AU (1) | AU728592B2 (pt) |
| CA (1) | CA2259655C (pt) |
| DE (1) | DE69717109T2 (pt) |
| DK (1) | DK0912515T3 (pt) |
| ES (1) | ES2182104T3 (pt) |
| HU (1) | HUP9904622A3 (pt) |
| IL (1) | IL127942A0 (pt) |
| NZ (1) | NZ333513A (pt) |
| PT (1) | PT912515E (pt) |
| WO (1) | WO1998001425A1 (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6251919B1 (en) * | 1998-02-27 | 2001-06-26 | Warner-Lambert | Heterocyclic substituted aniline calcium channel blockers |
| US6387930B1 (en) | 1999-05-04 | 2002-05-14 | Schering Corporation | Piperidine derivatives useful as CCR5 antagonists |
| ES2246233T3 (es) * | 1999-05-04 | 2006-02-16 | Schering Corporation | Derivados de piperidina utiles como antagonistas de ccr5. |
| US6635646B1 (en) | 1999-05-04 | 2003-10-21 | Schering Corporation | Pegylated interferon alfa-CCR5 antagonist combination HIV therapy |
| AR033517A1 (es) | 2000-04-08 | 2003-12-26 | Astrazeneca Ab | Derivados de piperidina, proceso para su preparacion y uso de estos derivados en la fabricacion de medicamentos |
| JP3942897B2 (ja) | 2000-04-28 | 2007-07-11 | エフ．ホフマン−ラ ロシュ アーゲー | ｐ−（スルホニル）アリール及びヘテロアリール |
| US6640155B2 (en) | 2000-08-22 | 2003-10-28 | Lam Research Corporation | Chemical mechanical polishing apparatus and methods with central control of polishing pressure applied by polishing head |
| BR0210733A (pt) | 2001-07-02 | 2004-07-20 | Astrazeneca Ab | Derivados de piperidina de utilidade úteis como moduladores da atividade do receptor de quimocina |
| GB0120461D0 (en) | 2001-08-22 | 2001-10-17 | Astrazeneca Ab | Novel compounds |
| AR036366A1 (es) | 2001-08-29 | 2004-09-01 | Schering Corp | Derivados de piperidina utiles como antagonistas de ccr5, composiciones farmaceuticas, el uso de dichos derivados para la fabricación de un medicamento y un kit |
| GB0122503D0 (en) | 2001-09-18 | 2001-11-07 | Astrazeneca Ab | Chemical compounds |
| WO2003048125A1 (en) | 2001-12-03 | 2003-06-12 | F. Hoffmann-La Roche Ag | Aminotetralin derivatives as muscarinic receptor antagonists |
| SE0200843D0 (sv) | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
| SE0200844D0 (sv) | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
| SI2389937T1 (sl) | 2002-06-14 | 2018-10-30 | Toyama Chemical Co., Ltd, | Farmacevtska sestava za izboljšanje možganske funkcije |
| SE0202838D0 (sv) * | 2002-09-24 | 2002-09-24 | Astrazeneca Ab | Chemical compounds |
| GB0223223D0 (en) * | 2002-10-07 | 2002-11-13 | Novartis Ag | Organic compounds |
| SE0300957D0 (sv) | 2003-04-01 | 2003-04-01 | Astrazeneca Ab | Chemical compounds |
| RU2008105987A (ru) | 2005-07-21 | 2009-08-27 | Астразенека Аб (Se) | Новые пиперидиновые производные |
| EP1919895A2 (en) | 2005-08-02 | 2008-05-14 | Lexicon Pharmaceuticals, Inc. | 2-aminoaryl pyridines as protein kinases inhibitors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1042029C (zh) * | 1993-07-28 | 1999-02-10 | 参天制药株式会社 | 1,4－(二苯基烷基)哌嗪衍生物及含有它的药物组合物 |
| IL117149A0 (en) * | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
-
1997
- 1997-07-08 NZ NZ333513A patent/NZ333513A/xx unknown
- 1997-07-08 CA CA002259655A patent/CA2259655C/en not_active Expired - Fee Related
- 1997-07-08 PT PT97932321T patent/PT912515E/pt unknown
- 1997-07-08 JP JP10505232A patent/JP3068206B2/ja not_active Expired - Fee Related
- 1997-07-08 AT AT97932321T patent/ATE227708T1/de not_active IP Right Cessation
- 1997-07-08 EP EP97932321A patent/EP0912515B1/en not_active Expired - Lifetime
- 1997-07-08 IL IL12794297A patent/IL127942A0/xx unknown
- 1997-07-08 WO PCT/US1997/011176 patent/WO1998001425A1/en active IP Right Grant
- 1997-07-08 AU AU35810/97A patent/AU728592B2/en not_active Ceased
- 1997-07-08 DE DE69717109T patent/DE69717109T2/de not_active Expired - Fee Related
- 1997-07-08 DK DK97932321T patent/DK0912515T3/da active
- 1997-07-08 ES ES97932321T patent/ES2182104T3/es not_active Expired - Lifetime
- 1997-07-08 HU HU9904622A patent/HUP9904622A3/hu unknown
-
1999
- 1999-01-07 KR KR1019997000045A patent/KR20000023599A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0912515B1 (en) | 2002-11-13 |
| JP3068206B2 (ja) | 2000-07-24 |
| DK0912515T3 (da) | 2003-03-10 |
| KR20000023599A (ko) | 2000-04-25 |
| IL127942A0 (en) | 1999-11-30 |
| WO1998001425A1 (en) | 1998-01-15 |
| HUP9904622A3 (en) | 2001-07-30 |
| DE69717109D1 (de) | 2002-12-19 |
| CA2259655A1 (en) | 1998-01-15 |
| NZ333513A (en) | 2000-04-28 |
| JPH11514671A (ja) | 1999-12-14 |
| DE69717109T2 (de) | 2003-04-30 |
| AU728592B2 (en) | 2001-01-11 |
| AU3581097A (en) | 1998-02-02 |
| ATE227708T1 (de) | 2002-11-15 |
| HUP9904622A2 (hu) | 2000-06-28 |
| ES2182104T3 (es) | 2003-03-01 |
| CA2259655C (en) | 2003-05-13 |
| EP0912515A1 (en) | 1999-05-06 |
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