PT912515E - Piperidinas 1,4-di-substituidas como antagonistas muscarinicos - Google Patents
Piperidinas 1,4-di-substituidas como antagonistas muscarinicosInfo
- Publication number
- PT912515E PT912515E PT97932321T PT97932321T PT912515E PT 912515 E PT912515 E PT 912515E PT 97932321 T PT97932321 T PT 97932321T PT 97932321 T PT97932321 T PT 97932321T PT 912515 E PT912515 E PT 912515E
- Authority
- PT
- Portugal
- Prior art keywords
- alkyl
- cycloalkyl
- heteroaryl
- aryl
- alkylheteroaryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67861896A | 1996-07-10 | 1996-07-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT912515E true PT912515E (pt) | 2003-03-31 |
Family
ID=24723553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97932321T PT912515E (pt) | 1996-07-10 | 1997-07-08 | Piperidinas 1,4-di-substituidas como antagonistas muscarinicos |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0912515B1 (pt) |
| JP (1) | JP3068206B2 (pt) |
| KR (1) | KR20000023599A (pt) |
| AT (1) | ATE227708T1 (pt) |
| AU (1) | AU728592B2 (pt) |
| CA (1) | CA2259655C (pt) |
| DE (1) | DE69717109T2 (pt) |
| DK (1) | DK0912515T3 (pt) |
| ES (1) | ES2182104T3 (pt) |
| HU (1) | HUP9904622A3 (pt) |
| IL (1) | IL127942A0 (pt) |
| NZ (1) | NZ333513A (pt) |
| PT (1) | PT912515E (pt) |
| WO (1) | WO1998001425A1 (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999043658A1 (en) * | 1998-02-27 | 1999-09-02 | Warner-Lambert Company | Heterocyclic substituted aniline calcium channel blockers |
| US6635646B1 (en) | 1999-05-04 | 2003-10-21 | Schering Corporation | Pegylated interferon alfa-CCR5 antagonist combination HIV therapy |
| ATE299866T1 (de) * | 1999-05-04 | 2005-08-15 | Schering Corp | Piperidinderivate verwendbar als ccr5 antagonisten |
| US6387930B1 (en) | 1999-05-04 | 2002-05-14 | Schering Corporation | Piperidine derivatives useful as CCR5 antagonists |
| AR033517A1 (es) | 2000-04-08 | 2003-12-26 | Astrazeneca Ab | Derivados de piperidina, proceso para su preparacion y uso de estos derivados en la fabricacion de medicamentos |
| JP3942897B2 (ja) | 2000-04-28 | 2007-07-11 | エフ．ホフマン−ラ ロシュ アーゲー | ｐ−（スルホニル）アリール及びヘテロアリール |
| US6640155B2 (en) | 2000-08-22 | 2003-10-28 | Lam Research Corporation | Chemical mechanical polishing apparatus and methods with central control of polishing pressure applied by polishing head |
| ES2258642T3 (es) | 2001-07-02 | 2006-09-01 | Astrazeneca Ab | Derivados de piperidina utiles como moduladores de la actividad del receptor de quimiocina. |
| GB0120461D0 (en) | 2001-08-22 | 2001-10-17 | Astrazeneca Ab | Novel compounds |
| AR036366A1 (es) | 2001-08-29 | 2004-09-01 | Schering Corp | Derivados de piperidina utiles como antagonistas de ccr5, composiciones farmaceuticas, el uso de dichos derivados para la fabricación de un medicamento y un kit |
| GB0122503D0 (en) | 2001-09-18 | 2001-11-07 | Astrazeneca Ab | Chemical compounds |
| CN100358870C (zh) | 2001-12-03 | 2008-01-02 | 弗·哈夫曼-拉罗切有限公司 | 作为毒蕈碱受体拮抗剂的氨基四氢萘衍生物 |
| SE0200844D0 (sv) | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
| SE0200843D0 (sv) | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
| BRPI0311780B8 (pt) | 2002-06-14 | 2021-05-25 | Toyama Chemical Co Ltd | composição farmacêutica para melhorar a função cerebral |
| SE0202838D0 (sv) * | 2002-09-24 | 2002-09-24 | Astrazeneca Ab | Chemical compounds |
| GB0223223D0 (en) * | 2002-10-07 | 2002-11-13 | Novartis Ag | Organic compounds |
| SE0300957D0 (sv) | 2003-04-01 | 2003-04-01 | Astrazeneca Ab | Chemical compounds |
| EP2402316A1 (en) | 2005-07-21 | 2012-01-04 | AstraZeneca AB (Publ) | Piperidine derivatives |
| BRPI0614262A2 (pt) | 2005-08-02 | 2011-03-15 | Lexicon Pharmaceuticals Inc | aril piridinas e métodos para uso das mesmas |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995004050A1 (fr) * | 1993-07-28 | 1995-02-09 | Santen Pharmaceutical Co., Ltd. | Nouveau derive de 1,4-di(phenylalkyl)piperazine |
| IL117149A0 (en) * | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
-
1997
- 1997-07-08 EP EP97932321A patent/EP0912515B1/en not_active Expired - Lifetime
- 1997-07-08 HU HU9904622A patent/HUP9904622A3/hu unknown
- 1997-07-08 JP JP10505232A patent/JP3068206B2/ja not_active Expired - Fee Related
- 1997-07-08 WO PCT/US1997/011176 patent/WO1998001425A1/en active IP Right Grant
- 1997-07-08 IL IL12794297A patent/IL127942A0/xx unknown
- 1997-07-08 NZ NZ333513A patent/NZ333513A/xx unknown
- 1997-07-08 AT AT97932321T patent/ATE227708T1/de not_active IP Right Cessation
- 1997-07-08 PT PT97932321T patent/PT912515E/pt unknown
- 1997-07-08 AU AU35810/97A patent/AU728592B2/en not_active Ceased
- 1997-07-08 CA CA002259655A patent/CA2259655C/en not_active Expired - Fee Related
- 1997-07-08 DK DK97932321T patent/DK0912515T3/da active
- 1997-07-08 ES ES97932321T patent/ES2182104T3/es not_active Expired - Lifetime
- 1997-07-08 DE DE69717109T patent/DE69717109T2/de not_active Expired - Fee Related
-
1999
- 1999-01-07 KR KR1019997000045A patent/KR20000023599A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0912515B1 (en) | 2002-11-13 |
| AU3581097A (en) | 1998-02-02 |
| ES2182104T3 (es) | 2003-03-01 |
| DE69717109D1 (de) | 2002-12-19 |
| WO1998001425A1 (en) | 1998-01-15 |
| JPH11514671A (ja) | 1999-12-14 |
| EP0912515A1 (en) | 1999-05-06 |
| CA2259655A1 (en) | 1998-01-15 |
| JP3068206B2 (ja) | 2000-07-24 |
| DE69717109T2 (de) | 2003-04-30 |
| AU728592B2 (en) | 2001-01-11 |
| KR20000023599A (ko) | 2000-04-25 |
| HUP9904622A2 (hu) | 2000-06-28 |
| NZ333513A (en) | 2000-04-28 |
| CA2259655C (en) | 2003-05-13 |
| ATE227708T1 (de) | 2002-11-15 |
| DK0912515T3 (da) | 2003-03-10 |
| IL127942A0 (en) | 1999-11-30 |
| HUP9904622A3 (en) | 2001-07-30 |
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