PT90339A - Processo para a preparacao de benzodiazepinas, uteis em terapia, e de intermediarios para esse fim - Google Patents
Processo para a preparacao de benzodiazepinas, uteis em terapia, e de intermediarios para esse fimInfo
- Publication number
- PT90339A PT90339A PT90339A PT9033989A PT90339A PT 90339 A PT90339 A PT 90339A PT 90339 A PT90339 A PT 90339A PT 9033989 A PT9033989 A PT 9033989A PT 90339 A PT90339 A PT 90339A
- Authority
- PT
- Portugal
- Prior art keywords
- benzodiazepines
- halogen
- intermediaries
- therapy
- preparation
- Prior art date
Links
- 229940049706 benzodiazepine Drugs 0.000 title abstract 2
- 150000001557 benzodiazepines Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 4
- 125000001041 indolyl group Chemical group 0.000 abstract 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8805443A FR2630440B1 (fr) | 1988-04-25 | 1988-04-25 | Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT90339A true PT90339A (pt) | 1989-11-10 |
| PT90339B PT90339B (pt) | 1994-08-31 |
Family
ID=9365634
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT90339A PT90339B (pt) | 1988-04-25 | 1989-04-21 | Processo para a preparacao de benzodiazepinas, uteis em terapia, e de intermediarios para esse fim |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4929614A (pt) |
| EP (1) | EP0340064B1 (pt) |
| JP (1) | JP2805634B2 (pt) |
| KR (1) | KR0142328B1 (pt) |
| AT (1) | ATE86995T1 (pt) |
| AU (1) | AU618086B2 (pt) |
| CA (1) | CA1340074C (pt) |
| DE (1) | DE68905365T2 (pt) |
| DK (1) | DK172664B1 (pt) |
| ES (1) | ES2054045T3 (pt) |
| FI (1) | FI91409C (pt) |
| FR (1) | FR2630440B1 (pt) |
| HK (1) | HK95496A (pt) |
| IE (1) | IE62663B1 (pt) |
| IS (1) | IS3454A7 (pt) |
| NO (1) | NO169653C (pt) |
| NZ (1) | NZ228650A (pt) |
| PT (1) | PT90339B (pt) |
| ZA (1) | ZA892682B (pt) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5248679A (en) * | 1988-09-09 | 1993-09-28 | Fujisawa Pharmaceutical Co., Ltd. | Tricyclic compounds |
| IL91361A (en) * | 1988-09-09 | 1994-10-07 | Fujisawa Pharmaceutical Co | Disubstituted 1,9-annelated [1,4] benzodiazepinone compounds, processes for the preparation thereof and pharmaceutical compositions containing the same |
| PH26955A (en) * | 1989-03-08 | 1992-12-03 | Kali Chemie Pharma Gmbh | Novel 1,7-fused 1H-indole-2-carboxylic acid N-(1,4-benzodiazepin-3-YL) amides |
| FR2652352A1 (fr) * | 1989-09-28 | 1991-03-29 | Jouveinal Sa | Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique. |
| IE904560A1 (en) * | 1989-12-18 | 1991-06-19 | Merck & Co Inc | New benzodiazepine analogs |
| GB9018601D0 (en) * | 1990-08-24 | 1990-10-10 | Fujisawa Pharmaceutical Co | Tricyclic compounds |
| US5206238A (en) * | 1990-11-13 | 1993-04-27 | Merck & Co., Inc. | Cholecystokinin antagonists |
| CA2056809A1 (en) * | 1990-12-07 | 1992-06-08 | Mark G. Bock | Benzodiazepine analogs |
| WO1994020143A1 (fr) * | 1993-03-03 | 1994-09-15 | Fujisawa Pharmaceutical Co., Ltd. | Inhibiteur d'isomerisation optique |
| WO1996006617A1 (en) * | 1994-08-30 | 1996-03-07 | Fujisawa Pharmaceutical Co., Ltd. | Liposome preparation |
| FR2725719B1 (fr) * | 1994-10-14 | 1996-12-06 | Jouveinal Inst Rech | Diazepino-indoles inhibiteurs de phosphodiesterases iv |
| FR2776660B1 (fr) * | 1998-03-27 | 2000-05-12 | Parke Davis | Diazepino-indoles de phosphodiesterases iv |
| HRP990246A2 (en) * | 1998-08-07 | 2000-06-30 | Du Pont Pharm Co | Succinoylamino benzodiazepines as inhibitors of a beta protein production |
| NZ509241A (en) | 1998-08-07 | 2003-08-29 | Du Pont Pharm Co | Succinoylamino lactams as inhibitors of alpha-beta protein production |
| US6787112B1 (en) * | 1998-08-13 | 2004-09-07 | Symyx Technologies, Inc. | Parallel reactor with internal sensing and method of using same |
| JP4615727B2 (ja) * | 1998-12-24 | 2011-01-19 | ブリストル−マイヤーズ スクイブ ファーマ カンパニー | Aβタンパク質生成の阻害剤としてのスクシノイルアミノベンゾジアゼピン |
| EP1222176A1 (en) * | 1999-10-08 | 2002-07-17 | Bristol-Myers Squibb Pharma Company | AMINO LACTAM SULFONAMIDES AS INHIBITORS OF A$g(b) PROTEIN PRODUCTION |
| US6525044B2 (en) * | 2000-02-17 | 2003-02-25 | Bristol-Myers Squibb Company | Succinoylamino carbocycles and heterocycles as inhibitors of a-β protein production |
| AU2001253090A1 (en) * | 2000-04-03 | 2001-10-15 | Bristol-Myers Squibb Pharma Company | Cyclic lactams as inhibitors of abeta protein production |
| US6692708B2 (en) * | 2001-04-05 | 2004-02-17 | Symyx Technologies, Inc. | Parallel reactor for sampling and conducting in situ flow-through reactions and a method of using same |
| KR101155335B1 (ko) * | 2005-01-07 | 2012-06-11 | 엘지전자 주식회사 | 이동통신 단말기의 멀티미디어 메시지 동작방법 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1332410C (en) * | 1984-06-26 | 1994-10-11 | Roger M. Freidinger | Benzodiazepine analogs |
| IL91361A (en) * | 1988-09-09 | 1994-10-07 | Fujisawa Pharmaceutical Co | Disubstituted 1,9-annelated [1,4] benzodiazepinone compounds, processes for the preparation thereof and pharmaceutical compositions containing the same |
| FR2652352A1 (fr) * | 1989-09-28 | 1991-03-29 | Jouveinal Sa | Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique. |
-
1988
- 1988-04-25 FR FR8805443A patent/FR2630440B1/fr not_active Expired - Lifetime
-
1989
- 1989-04-04 IE IE106789A patent/IE62663B1/en not_active IP Right Cessation
- 1989-04-07 IS IS3454A patent/IS3454A7/is unknown
- 1989-04-07 NZ NZ228650A patent/NZ228650A/en unknown
- 1989-04-07 ES ES89400969T patent/ES2054045T3/es not_active Expired - Lifetime
- 1989-04-07 AT AT89400969T patent/ATE86995T1/de not_active IP Right Cessation
- 1989-04-07 DE DE89400969T patent/DE68905365T2/de not_active Expired - Fee Related
- 1989-04-07 EP EP89400969A patent/EP0340064B1/fr not_active Expired - Lifetime
- 1989-04-12 ZA ZA892682A patent/ZA892682B/xx unknown
- 1989-04-14 US US07/337,940 patent/US4929614A/en not_active Expired - Lifetime
- 1989-04-14 AU AU33025/89A patent/AU618086B2/en not_active Ceased
- 1989-04-21 PT PT90339A patent/PT90339B/pt not_active IP Right Cessation
- 1989-04-24 DK DK198901972A patent/DK172664B1/da not_active IP Right Cessation
- 1989-04-24 NO NO891692A patent/NO169653C/no not_active IP Right Cessation
- 1989-04-24 CA CA000597603A patent/CA1340074C/en not_active Expired - Fee Related
- 1989-04-25 KR KR1019890005408A patent/KR0142328B1/ko not_active Expired - Fee Related
- 1989-04-25 JP JP1103583A patent/JP2805634B2/ja not_active Expired - Fee Related
- 1989-04-25 FI FI891952A patent/FI91409C/fi not_active IP Right Cessation
-
1996
- 1996-05-30 HK HK95496A patent/HK95496A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ228650A (en) | 1990-12-21 |
| FR2630440A1 (fr) | 1989-10-27 |
| FI891952A7 (fi) | 1989-10-26 |
| FI891952A0 (fi) | 1989-04-25 |
| KR900016158A (ko) | 1990-11-12 |
| AU618086B2 (en) | 1991-12-12 |
| NO169653C (no) | 1992-07-22 |
| IS3454A7 (is) | 1989-10-26 |
| DE68905365T2 (de) | 1993-10-14 |
| CA1340074C (en) | 1998-10-06 |
| ATE86995T1 (de) | 1993-04-15 |
| FI91409C (fi) | 1994-06-27 |
| NO169653B (no) | 1992-04-13 |
| ZA892682B (en) | 1990-12-28 |
| US4929614A (en) | 1990-05-29 |
| DK197289D0 (da) | 1989-04-24 |
| EP0340064B1 (fr) | 1993-03-17 |
| JPH0215083A (ja) | 1990-01-18 |
| FI91409B (fi) | 1994-03-15 |
| DE68905365D1 (de) | 1993-04-22 |
| EP0340064A1 (fr) | 1989-11-02 |
| NO891692L (no) | 1989-10-26 |
| ES2054045T3 (es) | 1994-08-01 |
| DK197289A (da) | 1989-10-26 |
| KR0142328B1 (ko) | 1998-06-01 |
| DK172664B1 (da) | 1999-05-10 |
| NO891692D0 (no) | 1989-04-24 |
| AU3302589A (en) | 1989-10-26 |
| FR2630440B1 (fr) | 1991-09-20 |
| IE891067L (en) | 1989-10-25 |
| HK95496A (en) | 1996-06-07 |
| PT90339B (pt) | 1994-08-31 |
| JP2805634B2 (ja) | 1998-09-30 |
| IE62663B1 (en) | 1995-02-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19940202 |
|
| MM3A | Annulment or lapse |
Effective date: 20050802 |