PT90066A - Processo para a preparacao de compostos que inibem a biosintese de metabolitos do acido araquidonico derivados de lipoxigenase - Google Patents
Processo para a preparacao de compostos que inibem a biosintese de metabolitos do acido araquidonico derivados de lipoxigenaseInfo
- Publication number
- PT90066A PT90066A PT90066A PT9006689A PT90066A PT 90066 A PT90066 A PT 90066A PT 90066 A PT90066 A PT 90066A PT 9006689 A PT9006689 A PT 9006689A PT 90066 A PT90066 A PT 90066A
- Authority
- PT
- Portugal
- Prior art keywords
- biasintese
- lipoxigenase
- metabolites
- inhibit
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/205—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing only six-membered aromatic rings as cyclic parts with unsaturation outside the rings
- C07C39/21—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing only six-membered aromatic rings as cyclic parts with unsaturation outside the rings with at least one hydroxy group on a non-condensed ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/24—Halogenated derivatives
- C07C39/373—Halogenated derivatives with all hydroxy groups on non-condensed rings and with unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/562—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom
- C07C45/565—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom by reaction with hexamethylene-tetramine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17051288A | 1988-03-21 | 1988-03-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT90066A true PT90066A (pt) | 1989-11-10 |
| PT90066B PT90066B (pt) | 1994-05-31 |
Family
ID=22620151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT90066A PT90066B (pt) | 1988-03-21 | 1989-03-21 | Processo para a preparacao de compostos que inibem a biosintese de metabolitos do acido araquidonico derivados de lipoxigenase |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0334119B1 (pt) |
| JP (1) | JPH024729A (pt) |
| KR (1) | KR890014514A (pt) |
| AU (1) | AU628324B2 (pt) |
| DD (1) | DD283602A5 (pt) |
| DE (1) | DE68907095T2 (pt) |
| DK (1) | DK134489A (pt) |
| ES (1) | ES2056983T3 (pt) |
| FI (1) | FI891295A (pt) |
| HU (2) | HU9201174D0 (pt) |
| IL (1) | IL89666A0 (pt) |
| NO (1) | NO169648C (pt) |
| NZ (1) | NZ228410A (pt) |
| PH (1) | PH26928A (pt) |
| PT (1) | PT90066B (pt) |
| ZA (1) | ZA892086B (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0626955A1 (en) * | 1992-02-11 | 1994-12-07 | Allergan, Inc. | Heteroaryl substituted phenylethenyl compounds having retinoid-like biological activity |
| ES2089736T3 (es) * | 1992-10-28 | 1996-10-01 | Shionogi & Co | Derivados de bencilideno. |
| ES2087019B1 (es) * | 1994-02-08 | 1997-03-16 | Bobel246 S L | Uso de derivados de fenoles 2,4-disubstituidos como inhibidores de la 5-lipoxigenasa. |
| TW544448B (en) * | 1997-07-11 | 2003-08-01 | Novartis Ag | Pyridine derivatives |
| US6376524B1 (en) * | 2000-06-21 | 2002-04-23 | Sunesis Pharmaceuticals, Inc. | Triphenyl compounds as interleukin-4 antagonists |
| ES2401077T3 (es) | 2001-01-18 | 2013-04-16 | Glaxo Group Limited | Nuevos derivados 1,2-difenileteno para el tratamiento de enfermedades inmunológicas |
| MXPA04000695A (es) | 2001-07-23 | 2005-08-26 | Galileo Pharmaceuticals Inc | Compuestos citoprotectores, formulaciones farmaceuticas y cosmeticas y metodos. |
| US20070185217A1 (en) | 2003-12-23 | 2007-08-09 | Abraxis Bioscience, Inc. | Propofol analogs, process for their preparation, and methods of use |
| WO2006078941A2 (en) * | 2005-01-20 | 2006-07-27 | Sirtris Pharmaceuticals, Inc. | Novel sirtuin activating compounds and methods of use thereof |
| EP3706725A4 (en) | 2017-11-10 | 2021-08-25 | Dermavant Sciences GmbH | PROCESS FOR THE PREPARATION OF TAPINAROF |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3188315A (en) * | 1960-05-18 | 1965-06-08 | Schering Corp | Novel compounds for lowering blood cholesterol levels |
| FR1390978A (fr) * | 1963-11-20 | 1965-03-05 | Ind Chimique Sa | Procédé de préparation de l'alpha-(thiényl-2) 4-hydroxystilbène et de quelques dérivés et produits obtenus |
| US4758586A (en) * | 1985-02-01 | 1988-07-19 | Usv Pharmaceutical Corp. | Indolyl compounds and hyposensitivity use thereof |
| DE3602473A1 (de) * | 1986-01-28 | 1987-07-30 | Basf Ag | Vinylphenolderivate, ihre herstellung und verwendung |
| US4743606A (en) * | 1986-03-25 | 1988-05-10 | Boehringer Ingelheim Pharmaceuticals, Inc. | 3-[2-(3',5'-di-t-butyl-4'-hydroxyphenyl)ethenyl]pyridine having anti-inflammatory and anti-arthritic properties |
| US4851423A (en) * | 1986-12-10 | 1989-07-25 | Schering Corporation | Pharmaceutically active compounds |
| CA1338645C (en) * | 1987-01-06 | 1996-10-15 | George R. Pettit | Isolation, structural elucidation and synthesis of novel antineoplastic substances denominated "combretastatins" |
-
1989
- 1989-03-10 DE DE89104251T patent/DE68907095T2/de not_active Expired - Fee Related
- 1989-03-10 ES ES89104251T patent/ES2056983T3/es not_active Expired - Lifetime
- 1989-03-10 EP EP89104251A patent/EP0334119B1/en not_active Expired - Lifetime
- 1989-03-15 NO NO891114A patent/NO169648C/no unknown
- 1989-03-20 HU HU9201174A patent/HU9201174D0/hu active Pending
- 1989-03-20 AU AU31514/89A patent/AU628324B2/en not_active Ceased
- 1989-03-20 DD DD89326756A patent/DD283602A5/de not_active IP Right Cessation
- 1989-03-20 NZ NZ228410A patent/NZ228410A/xx unknown
- 1989-03-20 FI FI891295A patent/FI891295A/fi not_active Application Discontinuation
- 1989-03-20 JP JP1069109A patent/JPH024729A/ja active Pending
- 1989-03-20 IL IL89666A patent/IL89666A0/xx unknown
- 1989-03-20 HU HU891323A patent/HU207858B/hu not_active IP Right Cessation
- 1989-03-20 KR KR1019890003422A patent/KR890014514A/ko not_active Application Discontinuation
- 1989-03-20 DK DK134489A patent/DK134489A/da not_active Application Discontinuation
- 1989-03-20 ZA ZA892086A patent/ZA892086B/xx unknown
- 1989-03-21 PH PH38366A patent/PH26928A/en unknown
- 1989-03-21 PT PT90066A patent/PT90066B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT90066B (pt) | 1994-05-31 |
| KR890014514A (ko) | 1989-10-24 |
| HU9201174D0 (en) | 1992-07-28 |
| ES2056983T3 (es) | 1994-10-16 |
| FI891295A0 (fi) | 1989-03-20 |
| DE68907095D1 (de) | 1993-07-22 |
| ZA892086B (en) | 1990-11-28 |
| IL89666A0 (en) | 1989-09-28 |
| FI891295A (fi) | 1989-09-22 |
| DK134489D0 (da) | 1989-03-20 |
| EP0334119A1 (en) | 1989-09-27 |
| AU3151489A (en) | 1989-09-21 |
| HUT50093A (en) | 1989-12-28 |
| EP0334119B1 (en) | 1993-06-16 |
| DK134489A (da) | 1989-09-22 |
| DE68907095T2 (de) | 1994-01-05 |
| PH26928A (en) | 1992-12-03 |
| JPH024729A (ja) | 1990-01-09 |
| AU628324B2 (en) | 1992-09-17 |
| DD283602A5 (de) | 1990-10-17 |
| NZ228410A (en) | 1993-08-26 |
| NO891114L (no) | 1989-09-22 |
| NO891114D0 (no) | 1989-03-15 |
| NO169648C (no) | 1992-07-22 |
| HU207858B (en) | 1993-06-28 |
| NO169648B (no) | 1992-04-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19931110 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19950531 |