PT88372A - Cellules eucaryotes recombinees productries d'interleukine-2-procede et vecteurs pour leur obtention et procede d'obtention d'interleukine-2 - Google Patents

Cellules eucaryotes recombinees productries d'interleukine-2-procede et vecteurs pour leur obtention et procede d'obtention d'interleukine-2

Info

Publication number
PT88372A
PT88372A PT88372A PT8837288A PT88372A PT 88372 A PT88372 A PT 88372A PT 88372 A PT88372 A PT 88372A PT 8837288 A PT8837288 A PT 8837288A PT 88372 A PT88372 A PT 88372A
Authority
PT
Portugal
Prior art keywords
interleukine
procede
obtention
recombinees
productries
Prior art date
Application number
PT88372A
Other languages
English (en)
Other versions
PT88372B (pt
Inventor
Johannes Lupker
Brigitte Miloux
Willem Roskam
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of PT88372A publication Critical patent/PT88372A/pt
Publication of PT88372B publication Critical patent/PT88372B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/55IL-2
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
PT88372A 1987-09-01 1988-08-30 Celulas eucarioticas recombinamtes produtoras de interleuquina-2,processo e vectores para a sua obtencao e processo para a obtencao de interleuquina-2 PT88372B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8712166A FR2619719B1 (fr) 1987-09-01 1987-09-01 Procede d'obtention d'interleukine-2 a partir de cellules eucaryotes, vecteurs necessaires a sa mise en oeuvre et lignees cellulaires hautement productrices

Publications (2)

Publication Number Publication Date
PT88372A true PT88372A (pt) 1989-07-31
PT88372B PT88372B (pt) 1993-04-30

Family

ID=9354552

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88372A PT88372B (pt) 1987-09-01 1988-08-30 Celulas eucarioticas recombinamtes produtoras de interleuquina-2,processo e vectores para a sua obtencao e processo para a obtencao de interleuquina-2

Country Status (12)

Country Link
EP (1) EP0307285A1 (pt)
JP (1) JPH01165373A (pt)
KR (1) KR890005264A (pt)
AU (1) AU606453B2 (pt)
DK (1) DK467188A (pt)
FI (1) FI884036A (pt)
FR (1) FR2619719B1 (pt)
IL (1) IL87622A0 (pt)
NO (1) NO883883L (pt)
NZ (1) NZ225983A (pt)
PT (1) PT88372B (pt)
ZA (1) ZA886517B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992367A (en) * 1986-05-12 1991-02-12 Hoffmann-La Roche Inc. Enhanced expression of human interleukin-2 in mammalian cells
US5417970A (en) * 1988-10-21 1995-05-23 Sanofi Drugs containing a glycosylated interleukin-2
FR2639232A1 (fr) * 1988-10-21 1990-05-25 Sanofi Sa Medicaments contenant une interleukine-2 glycosylee
WO1990015142A1 (en) * 1989-06-09 1990-12-13 Gropep Pty. Ltd. Growth hormone fusion proteins
US5679771A (en) * 1990-02-13 1997-10-21 Gropep Pty. Ltd. Method for treating intestinal diseases
IL126121A0 (en) * 1996-05-01 1999-05-09 Genitope Corp Vaccines for treatment of lymphoma and leukemia
US5776746A (en) 1996-05-01 1998-07-07 Genitope Corporation Gene amplification methods
AU4424497A (en) * 1996-09-13 1998-04-02 Transkaryotic Therapies, Inc. Therapy for alpha-galactosidase a deficiency
US6083725A (en) * 1996-09-13 2000-07-04 Transkaryotic Therapies, Inc. Tranfected human cells expressing human α-galactosidase A protein
ATE243045T1 (de) 1997-11-20 2003-07-15 Vical Inc Behandlung von krebs durch verwendung von zytokin-exprimierender polynukleotiden und zusammensetzungen dafür
KR20020043448A (ko) * 2000-12-04 2002-06-10 리송알렉스인근 인터루킨-2 재조합 단백질 및 그의 제조방법
IL140110A0 (en) * 2000-12-05 2002-02-10 Applied Research Systems Improvement of homogeneity and secretion of recombinant proteins in mammalian systems
US20040071686A1 (en) 2002-04-25 2004-04-15 Treco Douglas A. Treatment of alpha-galactosidase A deficiency
MA40094B1 (fr) 2014-08-06 2022-05-31 Univ Miami Protéines de fusion de l'interleukine-2/récepteur alpha de l'interleukine-2 et procédés d'utilisation
EP3990479A4 (en) * 2019-06-26 2023-08-02 The Johns Hopkins University METHODS AND MATERIALS FOR TARGETED EXPANSION OF IMMUNE EFFECTOR CELLS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0172619A1 (en) * 1984-06-20 1986-02-26 Takeda Chemical Industries, Ltd. Novel transformant and use thereof
US4992367A (en) * 1986-05-12 1991-02-12 Hoffmann-La Roche Inc. Enhanced expression of human interleukin-2 in mammalian cells

Also Published As

Publication number Publication date
DK467188D0 (da) 1988-08-19
FR2619719A1 (fr) 1989-03-03
JPH01165373A (ja) 1989-06-29
AU606453B2 (en) 1991-02-07
KR890005264A (ko) 1989-05-13
FR2619719B1 (fr) 1991-05-10
IL87622A0 (en) 1989-01-31
ZA886517B (en) 1989-05-30
NO883883D0 (no) 1988-08-31
AU2179688A (en) 1989-03-02
FI884036A0 (fi) 1988-09-01
FI884036A (fi) 1989-03-02
EP0307285A1 (fr) 1989-03-15
NZ225983A (en) 1990-09-26
DK467188A (da) 1989-03-02
PT88372B (pt) 1993-04-30
NO883883L (no) 1989-03-02

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19921027

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19940430