FI884036A0 - Rekombinerade eukariotceller, vilka producerar interleukin-2, foerfarande och och vektorer foer deras framstaellning och foerfarande foer framstaellning av interleukin-2. - Google Patents

Rekombinerade eukariotceller, vilka producerar interleukin-2, foerfarande och och vektorer foer deras framstaellning och foerfarande foer framstaellning av interleukin-2.

Info

Publication number
FI884036A0
FI884036A0 FI884036A FI884036A FI884036A0 FI 884036 A0 FI884036 A0 FI 884036A0 FI 884036 A FI884036 A FI 884036A FI 884036 A FI884036 A FI 884036A FI 884036 A0 FI884036 A0 FI 884036A0
Authority
FI
Finland
Prior art keywords
interleukin
far
framstaelling
flear
eucariotceller
Prior art date
Application number
FI884036A
Other languages
English (en)
Other versions
FI884036A (fi
Inventor
Johannes Lupker
Brigitte Miloux
Willem Roskam
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of FI884036A0 publication Critical patent/FI884036A0/fi
Publication of FI884036A publication Critical patent/FI884036A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
FI884036A 1987-09-01 1988-09-01 Rekombinerade eukariotceller, vilka producerar interleukin-2, foerfarande och och vektorer foer deras framstaellning och foerfarande foer framstaellning av interleukin-2. FI884036A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8712166A FR2619719B1 (fr) 1987-09-01 1987-09-01 Procede d'obtention d'interleukine-2 a partir de cellules eucaryotes, vecteurs necessaires a sa mise en oeuvre et lignees cellulaires hautement productrices

Publications (2)

Publication Number Publication Date
FI884036A0 true FI884036A0 (fi) 1988-09-01
FI884036A FI884036A (fi) 1989-03-02

Family

ID=9354552

Family Applications (1)

Application Number Title Priority Date Filing Date
FI884036A FI884036A (fi) 1987-09-01 1988-09-01 Rekombinerade eukariotceller, vilka producerar interleukin-2, foerfarande och och vektorer foer deras framstaellning och foerfarande foer framstaellning av interleukin-2.

Country Status (12)

Country Link
EP (1) EP0307285A1 (fi)
JP (1) JPH01165373A (fi)
KR (1) KR890005264A (fi)
AU (1) AU606453B2 (fi)
DK (1) DK467188A (fi)
FI (1) FI884036A (fi)
FR (1) FR2619719B1 (fi)
IL (1) IL87622A0 (fi)
NO (1) NO883883L (fi)
NZ (1) NZ225983A (fi)
PT (1) PT88372B (fi)
ZA (1) ZA886517B (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992367A (en) * 1986-05-12 1991-02-12 Hoffmann-La Roche Inc. Enhanced expression of human interleukin-2 in mammalian cells
US5417970A (en) * 1988-10-21 1995-05-23 Sanofi Drugs containing a glycosylated interleukin-2
FR2639232A1 (fr) * 1988-10-21 1990-05-25 Sanofi Sa Medicaments contenant une interleukine-2 glycosylee
DE69021335T2 (de) * 1989-06-09 1996-04-11 Gropep Pty. Ltd., Adelaide Wachstumshormonfusionsproteine.
US5679771A (en) * 1990-02-13 1997-10-21 Gropep Pty. Ltd. Method for treating intestinal diseases
IL126121A0 (en) * 1996-05-01 1999-05-09 Genitope Corp Vaccines for treatment of lymphoma and leukemia
US5776746A (en) 1996-05-01 1998-07-07 Genitope Corporation Gene amplification methods
US6083725A (en) 1996-09-13 2000-07-04 Transkaryotic Therapies, Inc. Tranfected human cells expressing human α-galactosidase A protein
HU230275B1 (hu) * 1996-09-13 2015-11-30 Shire Human Genetic Therapies, Inc Eljárás tisztított humán alfa-galaktozidáz-A készítmények előállítására, és a tisztított készítményeket tartalmazó gyógyászati készítmények, alfa-gal-A-deficienciából eredő rendellenességek kezelésében történő alkalmazásra
EP1987845B1 (en) 1997-11-20 2012-03-21 Vical Incorporated Treatment of cancer using cytokine-expressing polynucleotides and compositions therefor.
KR20020043448A (ko) * 2000-12-04 2002-06-10 리송알렉스인근 인터루킨-2 재조합 단백질 및 그의 제조방법
IL140110A0 (en) * 2000-12-05 2002-02-10 Applied Research Systems Improvement of homogeneity and secretion of recombinant proteins in mammalian systems
JP5570677B2 (ja) 2002-04-25 2014-08-13 シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド α−ガラクトシダーゼＡ欠損症の治療
MA40094B1 (fr) 2014-08-06 2022-05-31 Univ Miami Protéines de fusion de l'interleukine-2/récepteur alpha de l'interleukine-2 et procédés d'utilisation
WO2020264321A1 (en) * 2019-06-26 2020-12-30 The Johns Hopkins University Methods and materials for targeted expansion of immune effector cells

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0172619A1 (en) * 1984-06-20 1986-02-26 Takeda Chemical Industries, Ltd. Novel transformant and use thereof
US4992367A (en) * 1986-05-12 1991-02-12 Hoffmann-La Roche Inc. Enhanced expression of human interleukin-2 in mammalian cells

Also Published As

Publication number Publication date
IL87622A0 (en) 1989-01-31
JPH01165373A (ja) 1989-06-29
NO883883L (no) 1989-03-02
DK467188D0 (da) 1988-08-19
NO883883D0 (no) 1988-08-31
PT88372B (pt) 1993-04-30
FR2619719B1 (fr) 1991-05-10
ZA886517B (en) 1989-05-30
NZ225983A (en) 1990-09-26
FR2619719A1 (fr) 1989-03-03
AU606453B2 (en) 1991-02-07
KR890005264A (ko) 1989-05-13
DK467188A (da) 1989-03-02
EP0307285A1 (fr) 1989-03-15
PT88372A (pt) 1989-07-31
FI884036A (fi) 1989-03-02
AU2179688A (en) 1989-03-02

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Legal Events

Date Code Title Description
FA Application withdrawn

Owner name: SANOFI