GB8806073D0 - 4-benzylthiophene(or furan)-2-sulfonamides as antiglaucoma agents - Google Patents

4-benzylthiophene(or furan)-2-sulfonamides as antiglaucoma agents

Info

Publication number
GB8806073D0
GB8806073D0 GB888806073A GB8806073A GB8806073D0 GB 8806073 D0 GB8806073 D0 GB 8806073D0 GB 888806073 A GB888806073 A GB 888806073A GB 8806073 A GB8806073 A GB 8806073A GB 8806073 D0 GB8806073 D0 GB 8806073D0
Authority
GB
United Kingdom
Prior art keywords
benzylthiophene
sulfonamides
furan
antiglaucoma agents
antiglaucoma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB888806073A
Other versions
GB2202532A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB8806073D0 publication Critical patent/GB8806073D0/en
Publication of GB2202532A publication Critical patent/GB2202532A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/64—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB08806073A 1987-03-23 1988-03-15 4-benzylthiophene(or furan)-2-sulfonamides as antiglaucoma agents Withdrawn GB2202532A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/028,825 US4914111A (en) 1987-03-23 1987-03-23 4-Benzylthiophene (or furan)-2-sulfonamides as antiglaucoma agents

Publications (2)

Publication Number Publication Date
GB8806073D0 true GB8806073D0 (en) 1988-04-13
GB2202532A GB2202532A (en) 1988-09-28

Family

ID=21845670

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08806073A Withdrawn GB2202532A (en) 1987-03-23 1988-03-15 4-benzylthiophene(or furan)-2-sulfonamides as antiglaucoma agents

Country Status (2)

Country Link
US (1) US4914111A (en)
GB (1) GB2202532A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935528A (en) * 1985-06-07 1990-06-19 Ishihara Sangyo Kaisha Ltd. Thiophenesulfonamide compounds, herbicidal compositions containing them, and process for their production
US5300499A (en) * 1992-09-02 1994-04-05 Allergan, Inc. 5-substituted 3-thiophene sulfonamides as antiglaucoma agents
US5629345A (en) * 1993-07-23 1997-05-13 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
US5965620A (en) * 1993-07-23 1999-10-12 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4416890A (en) * 1981-07-13 1983-11-22 Merck & Co., Inc. Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure
US4386098A (en) * 1981-11-03 1983-05-31 Merck & Co., Inc. 6-Hydroxy-2-benzothiazolesulfonamide for the topical treatment of elevated intraocular pressure
US4426388A (en) * 1982-04-02 1984-01-17 Merck & Co., Inc. 5-Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure
US4477466A (en) * 1983-05-23 1984-10-16 Merck & Co., Inc. Acyloxy derivatives of [phenylsulfonyl(or sulfinyl)]thiophenesulfonamide for the topical treatment of elevated intraocular pressure
US4542152A (en) * 1983-05-23 1985-09-17 Merck & Co., Inc. 5-[Phenylsulfonyl(or sulfinyl)]thiophene-2-sulfonamides for the topical treatment of elevated intraocular pressure
US4585787A (en) * 1983-06-20 1986-04-29 Merck & Co., Inc. 5-[2(Or 3)-hydroxyphenylsulfonyl]thiophene-2-sulfonamides for the topical treatment of elevated intraocular pressure
US4486444A (en) * 1983-06-20 1984-12-04 Merck & Co., Inc. (Hydroxybenzoyl)thiophenesulfonamide and acyl derivatives thereof for the topical treatment of elevated intraocular pressure
US4544667A (en) * 1984-02-09 1985-10-01 Merck & Co., Inc. 2-Sulfamoylbenzo[b]furan derivatives for the treatment of elevated intraocular pressure
US4665090A (en) * 1985-10-09 1987-05-12 Merck & Co., Inc. Substituted thiophene-2-sulfonamide antiglaucoma agents

Also Published As

Publication number Publication date
US4914111A (en) 1990-04-03
GB2202532A (en) 1988-09-28

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)