PT87086A - Active specific immune suppression - Google Patents

Active specific immune suppression

Info

Publication number
PT87086A
PT87086A PT87086A PT8708688A PT87086A PT 87086 A PT87086 A PT 87086A PT 87086 A PT87086 A PT 87086A PT 8708688 A PT8708688 A PT 8708688A PT 87086 A PT87086 A PT 87086A
Authority
PT
Portugal
Prior art keywords
mammal
cells
immune system
specific immune
immune suppression
Prior art date
Application number
PT87086A
Other languages
English (en)
Other versions
PT87086B (pt
Inventor
Richard L Edelson
Daniel J Tripodi
Original Assignee
Therakos Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therakos Inc filed Critical Therakos Inc
Publication of PT87086A publication Critical patent/PT87086A/pt
Publication of PT87086B publication Critical patent/PT87086B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4621—Cellular immunotherapy characterized by the effect or the function of the cells immunosuppressive or immunotolerising
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/46433—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/46434—Antigens related to induction of tolerance to non-self
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0066—Psoralene-activated UV-A photochemotherapy (PUVA-therapy), e.g. for treatment of psoriasis or eczema, extracorporeal photopheresis with psoralens or fucocoumarins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT87086A 1987-03-27 1988-03-25 Processo para a preparacao de um agente terapeutico para a supressao do sistema imunologico PT87086B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/031,490 US4838852A (en) 1987-03-27 1987-03-27 Active specific immune suppression

Publications (2)

Publication Number Publication Date
PT87086A true PT87086A (pt) 1988-04-01
PT87086B PT87086B (pt) 1992-07-31

Family

ID=21859747

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87086A PT87086B (pt) 1987-03-27 1988-03-25 Processo para a preparacao de um agente terapeutico para a supressao do sistema imunologico

Country Status (10)

Country Link
US (1) US4838852A (pt)
EP (1) EP0284409A3 (pt)
JP (1) JP2958372B2 (pt)
AU (1) AU606666B2 (pt)
CA (1) CA1306678C (pt)
DK (1) DK166688A (pt)
GR (1) GR1000039B (pt)
PH (1) PH25590A (pt)
PT (1) PT87086B (pt)
ZA (1) ZA882159B (pt)

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US4960408A (en) * 1989-01-10 1990-10-02 Klainer Albert S Treatment methods and vaccines for stimulating an immunological response against retroviruses
IL92996A (en) * 1989-01-10 1996-06-18 Bisaccia Emil Photovoltaic compounds as drugs for the treatment of viral infections and a method for the production of vaccines
US5150705A (en) * 1989-07-12 1992-09-29 Stinson Randy L Apparatus and method for irradiating cells
US5503721A (en) 1991-07-18 1996-04-02 Hri Research, Inc. Method for photoactivation
US5116307A (en) * 1990-07-09 1992-05-26 Collins Harvey T Method and system for treatment of AIDS
JP3051998B2 (ja) * 1990-12-20 2000-06-12 バクスター、インターナショナル、インコーポレイテッド 光活性療法及び細胞分離技術を用いる血液のような液体中の遊離の及び同伴された汚染物を同時に除去するためのシステム並びに方法
EP0516836B1 (en) * 1990-12-20 1996-03-13 Baxter International Inc. A device and method for eradicating contaminants in fluids
JP3051996B2 (ja) * 1990-12-20 2000-06-12 バクスター、インターナショナル、インコーポレイテッド 液体中の汚染物を根絶するためのシステム
ZA919934B (en) * 1990-12-20 1992-09-30 Baxter Int Systems and methods for eradicating contaminants using photoactive materials in fluids like blood using discrete sources of radiation
US5263925A (en) * 1991-07-22 1993-11-23 Gilmore Jr Thomas F Photopheresis blood treatment
US6669965B2 (en) 1992-02-07 2003-12-30 Vasogen Ireland Limited Method of treating atherosclerosis
US5980954A (en) 1992-02-07 1999-11-09 Vasogen Ireland Limited Treatment of autoimmune diseases
US5651993A (en) * 1992-11-18 1997-07-29 Yale University Specific immune system modulation
US5820872A (en) * 1992-11-18 1998-10-13 Yale University Methods and compositions for improving the effectiveness of X-irradiation therapy for the treatment of an internal solid tumor
US5354774A (en) * 1992-12-24 1994-10-11 Yale University Inhibition of smooth muscle cell proliferation by 8-methoxypsoralen photoactivated by visible light
US5462733A (en) * 1993-02-04 1995-10-31 Yale University Immune system modulation using psoralens activated with visible light
RU2118177C1 (ru) * 1993-08-02 1998-08-27 Алексей Борисович Башкиров Способ индукции иммунного ответа организма
EP0699441A1 (de) * 1994-07-09 1996-03-06 Plewig, Gerd, Prof. Dr. med. Mittel zur Behandlung des atopischen Ekzems und Verfahren zur Herstellung desselben
US5527704A (en) 1994-12-06 1996-06-18 Baxter International Inc. Apparatus and method for inactivating viral contaminants in body fluids
US5882328A (en) * 1995-01-13 1999-03-16 Qlt Phototherapeutics, Inc. Method to prevent transplant rejection
US5789433A (en) * 1995-01-17 1998-08-04 Quadra Logic Technologies, Inc. Green porphyrins as immunomodulators
US6096776A (en) * 1995-01-17 2000-08-01 Qlt Phototherapeutics, Inc. Green porphyrins as immunomodulators
US6107325A (en) * 1995-01-17 2000-08-22 Qlt Phototherapeutics, Inc. Green porphyrins as immunomodulators
US5704888A (en) * 1995-04-14 1998-01-06 Cobe Laboratories, Inc. Intermittent collection of mononuclear cells in a centrifuge apparatus
US5704889A (en) * 1995-04-14 1998-01-06 Cobe Laboratories, Inc. Spillover collection of sparse components such as mononuclear cells in a centrifuge apparatus
WO1997036581A1 (en) * 1996-03-29 1997-10-09 Therakos, Inc. Photopheresis treatment of leukocytes
WO1997037536A1 (en) 1996-04-09 1997-10-16 Therakos, Inc. Method for removal of psoralens from biological fluids
EP0981371A1 (en) * 1997-05-16 2000-03-01 QLT Phototherapeutics, Inc. Green porphyrins as immunomodulators
IL133913A0 (en) * 1997-07-10 2001-04-30 Therakos Inc Treatment of inflammatory disorders of the bowel and urinary bladder
JP2003520563A (ja) * 1997-07-21 2003-07-08 シーラス コーポレイション 白血球を処置する方法、白血球組成物およびそれを使用する方法
US20080241815A1 (en) * 1999-04-20 2008-10-02 Edelson Richard L Methods for Inducing the Differentiation of Blood Monocytes into Functional Dendritic Cells
CA2368855C (en) 1999-04-20 2012-05-29 Richard Leslie Edelson Differentiation of monocytes into functional dendritic cells
US20050084966A1 (en) * 1999-04-20 2005-04-21 Edelson Richard L. Methods for inducing the differentiation of blood monocytes into functional dendritic cells
US7109031B2 (en) * 1999-04-20 2006-09-19 Yale University Methods for inducing the differentiation of monocytes into functional dendritic cells and immunotherapeutic compositions including such dendritic cells
US20050158856A1 (en) * 1999-04-20 2005-07-21 Edelson Richard L. Methods for producing functional antigen presenting dendritic cells using biodegradable microparticles for delivery of antigenic materials
US6219584B1 (en) 1999-07-09 2001-04-17 Therakos, Inc. Method and system for determining an effective amount of light energy to delivery to fluids having targets for the light energy
US6495366B1 (en) * 1999-09-03 2002-12-17 Therakos, Inc. Uninterrupted flow pump apparatus and method
US8722422B2 (en) 1999-09-03 2014-05-13 Therakos, Inc. Uninterrupted flow pump apparatus and method
US6793643B1 (en) 2000-04-21 2004-09-21 Therakos, Inc. Low extracorporeal volume treatment system
WO2002060376A2 (en) * 2001-01-31 2002-08-08 Tolaren Induction of tolerance by apoptotic and/or necrotic cells
US20050202098A1 (en) * 2001-01-31 2005-09-15 Tolaren Disease therapy using dying or dead cells
EP1399740A2 (en) * 2001-06-22 2004-03-24 The University of British Columbia Type 1 diabetes diagnostics and therapeutics
US20070129307A1 (en) * 2001-06-22 2007-06-07 The University Of British Columbia Insulin epitopes for the treatment of type 1 diabetes
EP1427462B1 (en) * 2001-08-13 2010-01-13 Yale University Method for inducing selectively suppressed immune response
AU2007200894B2 (en) * 2001-08-13 2009-10-29 Yale University Method for inducing selectively suppressed immune response
US7727523B2 (en) * 2001-08-13 2010-06-01 Yale University Method for suppressing immune system response to transplanted tissue or cells
US20030139466A1 (en) * 2001-11-29 2003-07-24 Peritt David L. Methods for pretreating a subject with extracorporeal photopheresis
AU2002360791A1 (en) * 2001-12-18 2003-06-30 Health Research, Inc. Method of enhancing immunogenicity by covalent linkage of antigens to proteins on the surface of dendritic cells
US7223368B2 (en) * 2002-05-03 2007-05-29 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
US7939078B2 (en) * 2005-07-07 2011-05-10 Codman & Shurtleff Methods of enhancing the immune response to autoantigens in mucosal associated lymphatic tissue
CA2620230A1 (en) * 2005-10-05 2007-04-12 Gambro Bct, Inc. Method and apparatus for leukoreduction of red blood cells
US20070087029A1 (en) * 2005-10-14 2007-04-19 Pakala Syamasundar V Localized delivery to the lymphatic system
US20080102505A1 (en) * 2006-09-18 2008-05-01 Petrie Thomas R Jr Method of treating viral infections with ultraviolet light
US9358292B2 (en) 2007-04-08 2016-06-07 Immunolight, Llc Methods and systems for treating cell proliferation disorders
US8524495B2 (en) * 2007-05-16 2013-09-03 Yale University Methods for inducing the differentiation of blood monocytes into functional dendritic cells
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EP2729175B1 (en) 2011-07-08 2021-12-01 Duke University System for light stimulation within a medium
US9399093B2 (en) 2012-01-27 2016-07-26 Fenwal, Inc. Systems and methods for performing online extracorporeal photopheresis
EP3097108B8 (en) 2014-01-23 2021-04-07 Immunolight, LLC Use of psoralen derivatives and combination therapy for treatment of cell proliferation disorders
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Also Published As

Publication number Publication date
PT87086B (pt) 1992-07-31
GR1000039B (el) 1990-03-12
PH25590A (en) 1991-08-08
AU1358488A (en) 1988-09-29
EP0284409A2 (en) 1988-09-28
AU606666B2 (en) 1991-02-14
ZA882159B (en) 1989-11-29
DK166688D0 (da) 1988-03-25
JP2958372B2 (ja) 1999-10-06
JPS63275525A (ja) 1988-11-14
GR880100184A (en) 1989-01-31
US4838852A (en) 1989-06-13
CA1306678C (en) 1992-08-25
EP0284409A3 (en) 1989-02-08
DK166688A (da) 1988-09-28

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FG3A Patent granted, date of granting

Effective date: 19920109

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

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Effective date: 20080325