PT84526A - Therapeutic agents - Google Patents

Therapeutic agents

Info

Publication number
PT84526A
PT84526A PT84526A PT8452687A PT84526A PT 84526 A PT84526 A PT 84526A PT 84526 A PT84526 A PT 84526A PT 8452687 A PT8452687 A PT 8452687A PT 84526 A PT84526 A PT 84526A
Authority
PT
Portugal
Prior art keywords
compaction
ibuprofen
composition
therapeutic agents
crystalline ibuprofen
Prior art date
Application number
PT84526A
Other languages
English (en)
Other versions
PT84526B (pt
Inventor
Keith Allan
Richard Michael Slater
David Wesley Bogan
Jivn-Ren Chen
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of PT84526A publication Critical patent/PT84526A/pt
Publication of PT84526B publication Critical patent/PT84526B/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
PT84526A 1986-03-19 1987-03-19 Processo para a preparacao de uma composicao solida compreendendo granulos consistindo essencialmente de um agregado de cristais de ibuprofeno PT84526B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868606762A GB8606762D0 (en) 1986-03-19 1986-03-19 Therapeutic agents

Publications (2)

Publication Number Publication Date
PT84526A true PT84526A (en) 1987-04-01
PT84526B PT84526B (pt) 1989-11-10

Family

ID=10594868

Family Applications (1)

Application Number Title Priority Date Filing Date
PT84526A PT84526B (pt) 1986-03-19 1987-03-19 Processo para a preparacao de uma composicao solida compreendendo granulos consistindo essencialmente de um agregado de cristais de ibuprofeno

Country Status (21)

Country Link
EP (1) EP0241126B1 (pt)
JP (1) JPS62230723A (pt)
KR (1) KR870008582A (pt)
CN (1) CN87101974A (pt)
AT (1) ATE65393T1 (pt)
AU (1) AU7017787A (pt)
CS (1) CS182787A2 (pt)
DD (1) DD263232A5 (pt)
DE (1) DE3771544D1 (pt)
DK (1) DK136487A (pt)
FI (1) FI871112A (pt)
GB (2) GB8606762D0 (pt)
HU (1) HU195422B (pt)
IL (1) IL81884A0 (pt)
IN (1) IN163939B (pt)
NO (1) NO871120L (pt)
NZ (1) NZ219560A (pt)
PL (1) PL264695A1 (pt)
PT (1) PT84526B (pt)
YU (1) YU47087A (pt)
ZA (1) ZA871836B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3833448A1 (de) * 1988-10-01 1990-04-12 Hoechst Ag Verfahren zur gewinnung von ibuprofen fuer die direkttablettierung
NZ234587A (en) * 1989-08-04 1991-11-26 Mcneil Ppc Inc A chewable pharmaceutical tablet of compressed coated granules
CA2063141C (en) * 1989-08-04 1997-03-04 Edward J. Roche Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
US5191114A (en) * 1991-10-09 1993-03-02 Sage Pharmaceuticals, Inc. Process for enhancing the flow characteristics of ibuprofen
US5605930A (en) * 1991-10-21 1997-02-25 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for treating and preventing pathologies including cancer
US5534262A (en) * 1992-01-10 1996-07-09 Dobrotvorsky; Anatoly E. Pharmaceutical granulated composition and method for preparing same
EG20677A (en) * 1993-10-01 1999-11-30 Astra Ag Method and an apparatus for micronizing the particle size
IS1736B (is) * 1993-10-01 1999-12-30 Astra Ab Aðferð og tæki sem stuðla að aukinni samloðun agna
TWI225402B (en) 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
FR2804603B1 (fr) * 2000-02-04 2004-01-23 Rhodia Chimie Sa Procede continu pour formuler sous forme de granules une ou plusieurs matieres actives pharmaceutiques
DE102005037630A1 (de) 2005-08-09 2007-02-15 Glatt Gmbh Verfahren zur Herstellung von Teilchen aus pharmazeutischen Substanzen, Teilchen aus pharmazeutischen Substanzen sowie deren Verwendung
WO2014078435A1 (en) 2012-11-14 2014-05-22 W. R. Grace & Co.-Conn. Compositions containing a biologically active material and a non-ordered inorganic oxide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476248A (en) * 1983-02-28 1984-10-09 The Upjohn Company Crystallization of ibuprofen
JPS60120616A (ja) * 1983-12-05 1985-06-28 Yaskawa Electric Mfg Co Ltd プリセット型可逆カウンタ装置
US4609675A (en) * 1984-08-17 1986-09-02 The Upjohn Company Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing

Also Published As

Publication number Publication date
PT84526B (pt) 1989-11-10
DE3771544D1 (de) 1991-08-29
NO871120D0 (no) 1987-03-18
AU7017787A (en) 1987-09-24
NO871120L (no) 1987-09-21
GB2187952B (en) 1990-05-09
IL81884A0 (en) 1987-10-20
CN87101974A (zh) 1987-10-21
IN163939B (pt) 1988-12-10
KR870008582A (ko) 1987-10-19
ATE65393T1 (de) 1991-08-15
HUT42939A (en) 1987-09-28
HU195422B (en) 1988-05-30
EP0241126A1 (en) 1987-10-14
FI871112A (fi) 1987-09-20
ZA871836B (en) 1987-09-02
JPS62230723A (ja) 1987-10-09
GB2187952A (en) 1987-09-23
GB8704987D0 (en) 1987-04-08
GB8606762D0 (en) 1986-04-23
DK136487D0 (da) 1987-03-17
NZ219560A (en) 1989-05-29
CS182787A2 (en) 1991-05-14
EP0241126B1 (en) 1991-07-24
YU47087A (en) 1988-04-30
PL264695A1 (en) 1988-05-12
FI871112A0 (fi) 1987-03-13
DD263232A5 (de) 1988-12-28
DK136487A (da) 1987-09-20

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