PT84206B - Processo para a preparacao de 1,4-di-hidropiridinas - Google Patents

Processo para a preparacao de 1,4-di-hidropiridinas

Info

Publication number
PT84206B
PT84206B PT84206A PT8420687A PT84206B PT 84206 B PT84206 B PT 84206B PT 84206 A PT84206 A PT 84206A PT 8420687 A PT8420687 A PT 8420687A PT 84206 B PT84206 B PT 84206B
Authority
PT
Portugal
Prior art keywords
optionally substituted
sub
formula
represent
group
Prior art date
Application number
PT84206A
Other languages
English (en)
Other versions
PT84206A (en
Inventor
Terence James Ward
John Leheup Archibald
Albert Opalko
Original Assignee
Wyeth John & Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd
Publication of PT84206A publication Critical patent/PT84206A/pt
Publication of PT84206B publication Critical patent/PT84206B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Manufacture Of Tobacco Products (AREA)
  • Saccharide Compounds (AREA)
PT84206A 1986-02-01 1987-01-28 Processo para a preparacao de 1,4-di-hidropiridinas PT84206B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868602518A GB8602518D0 (en) 1986-02-01 1986-02-01 1 4-dihydropyridines

Publications (2)

Publication Number Publication Date
PT84206A PT84206A (en) 1987-02-01
PT84206B true PT84206B (pt) 1989-11-30

Family

ID=10592383

Family Applications (1)

Application Number Title Priority Date Filing Date
PT84206A PT84206B (pt) 1986-02-01 1987-01-28 Processo para a preparacao de 1,4-di-hidropiridinas

Country Status (12)

Country Link
US (1) US5064842A (pt)
EP (1) EP0233015B1 (pt)
JP (1) JPH0723370B2 (pt)
KR (1) KR950003922B1 (pt)
AT (1) ATE129242T1 (pt)
CA (1) CA1329600C (pt)
DE (1) DE3751562T2 (pt)
ES (1) ES2078215T3 (pt)
GB (2) GB8602518D0 (pt)
GR (1) GR3018729T3 (pt)
HU (1) HU199139B (pt)
PT (1) PT84206B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2036128B1 (es) * 1991-07-10 1993-12-16 Menarini Lab Procedimiento para la preparacion de 4-(imidazo)1,5-a)piridin-8l)-1,4-dihidropiridinas.
US5288866A (en) * 1991-12-20 1994-02-22 American Cyanamid Company 5,6-disubstituted-3-pyridylmethyl ammonium halide compounds useful for the preparation of 5- (substituted methyl)-2,3-pyridinedicarboxylic acids

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2738153A1 (de) * 1977-08-24 1979-03-08 Bayer Ag 2-pyridyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
CA1117117A (en) * 1978-10-10 1982-01-26 Fujisawa Pharmaceutical Co., Ltd. 2-methyl-dihydropyridine compound, processes for preparation thereof and pharmaceutical composition comprising the same
EP0080220B1 (en) * 1981-11-17 1986-02-19 FISONS plc Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
EP0100189B1 (en) * 1982-07-22 1986-05-28 Pfizer Limited Dihydropyridine anti-ischaemic and antihypertensive agents
US4607041A (en) * 1983-04-27 1986-08-19 Fisons Plc Antihypertensive 2-phenyl Hantzsch dihydropyridines
GR851819B (pt) * 1984-08-17 1985-11-26 Wyeth John & Brother Ltd
EP0174131A3 (en) * 1984-09-01 1989-06-07 FISONS plc Dihydropyridines, processes and intermediates for their production, and pharmaceutical formulations containing them
EP0225175A3 (en) * 1985-11-28 1988-12-28 FISONS plc Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
EP0233015A3 (en) 1990-11-07
HUT45988A (en) 1988-09-28
EP0233015A2 (en) 1987-08-19
DE3751562D1 (de) 1995-11-23
ES2078215T3 (es) 1995-12-16
US5064842A (en) 1991-11-12
EP0233015B1 (en) 1995-10-18
GB8702016D0 (en) 1987-03-04
CA1329600C (en) 1994-05-17
PT84206A (en) 1987-02-01
HU199139B (en) 1990-01-29
KR950003922B1 (ko) 1995-04-20
JPS62201868A (ja) 1987-09-05
GB2185982A (en) 1987-08-05
GR3018729T3 (en) 1996-04-30
DE3751562T2 (de) 1996-04-11
JPH0723370B2 (ja) 1995-03-15
GB8602518D0 (en) 1986-03-05
ATE129242T1 (de) 1995-11-15
GB2185982B (en) 1990-05-16
KR870007889A (ko) 1987-09-22

Similar Documents

Publication Publication Date Title
AR010795A1 (es) Compuestos derivados de sulfonamidas, procedimiento para su preparacion y una composicion farmaceutica
ES2051693T3 (es) Procedimiento para preparar compuestos biciclos de sulfonamida.
ATE90107T1 (de) Peptide mit collagenase hemmender wirkung.
ES8604564A1 (es) Procedimiento de obtencion de derivados de 4-aril-1,4-dihi- dropiridinas
BR8502972A (pt) Processo para a preparacao de 5-amino-4-heterociclil-1-fenilpirazois,composicoes herbicidas,aplicacao,processos para a preparacao de composicoes e para a preparacao de derivados de acrilonitrila
ES466532A1 (es) Procedimiento para la obtencion de n-aridiazaciclos oxigena-dos.
GB8814813D0 (en) Novel compounds
ES2037668T3 (es) Un procedimiento para la produccion de compuestos benzotiazolilazolidinas.
DK337883A (da) Fremgangsmaade til fremstilling af muramylpeptider eller salte deraf
PT84206B (pt) Processo para a preparacao de 1,4-di-hidropiridinas
BR8904383A (pt) Composto polimerico,composicao sensivel a radiacao e processo para a producao de um composto polimerico
ATE81651T1 (de) Substituierte aromatische verbindungen mit zentraler nervensystem-wirkung.
ES551421A0 (es) Un procedimiento para preparar imidazol-5-carboximidatos
MX9605994A (es) Formilaminofenilsulfonilureas, metodos para prepararlos y su uso como herbicidas y reguladores de crecimiento de la plantas.
EP0253502A3 (en) Tertiary amine compounds
PT86832A (pt) Process for preparing glycine compounds
FI831193L (fi) Organosilylfoereningar och deras anvaendning som fungicider
ATE27955T1 (de) Verfahren und zwischenprodukte zur herstellung von 2-substituierten 4-acetyl-imidazolen.
ATE31404T1 (de) Verfahren zur herstellung von cycklopropanabkoemmlingen.
ES457575A2 (es) Procedimiento para la preparacion de un compuesto diarilico sulfurado ynu oxigenado.
JPS5732265A (en) Novel 4,4-disubstituted 1,4-dihydropyridine compound
MX9201575A (es) Compuestos novedosos.

Legal Events

Date Code Title Description
MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20011130