PT81299A - Process for preparing alkylsulfonamidophenylalkylamines - Google Patents

Process for preparing alkylsulfonamidophenylalkylamines

Info

Publication number
PT81299A
PT81299A PT81299A PT8129985A PT81299A PT 81299 A PT81299 A PT 81299A PT 81299 A PT81299 A PT 81299A PT 8129985 A PT8129985 A PT 8129985A PT 81299 A PT81299 A PT 81299A
Authority
PT
Portugal
Prior art keywords
alkylsulfonamidophenylalkylamines
preparing
preparing alkylsulfonamidophenylalkylamines
Prior art date
Application number
PT81299A
Other languages
English (en)
Other versions
PT81299B (pt
Inventor
Bryan Barnet Molloy
Mitchell Irvin Steinberg
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PT81299A publication Critical patent/PT81299A/pt
Publication of PT81299B publication Critical patent/PT81299B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/38Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reaction of ammonia or amines with sulfonic acids, or with esters, anhydrides, or halides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/08Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PT81299A 1984-10-15 1985-10-14 Processo para a preparacao de alquilsulfonamidofenilalquilaminas PT81299B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/660,816 US4569801A (en) 1984-10-15 1984-10-15 Alkylsulfonamidophenylalkylamines

Publications (2)

Publication Number Publication Date
PT81299A true PT81299A (en) 1985-11-01
PT81299B PT81299B (pt) 1988-02-17

Family

ID=24651088

Family Applications (1)

Application Number Title Priority Date Filing Date
PT81299A PT81299B (pt) 1984-10-15 1985-10-14 Processo para a preparacao de alquilsulfonamidofenilalquilaminas

Country Status (18)

Country Link
US (1) US4569801A (pt)
EP (1) EP0178874B1 (pt)
JP (1) JPS6197256A (pt)
KR (1) KR880001008B1 (pt)
CN (1) CN1004133B (pt)
AR (1) AR241528A1 (pt)
AT (1) ATE41922T1 (pt)
AU (1) AU586644B2 (pt)
CA (1) CA1291165C (pt)
DK (1) DK164450C (pt)
ES (1) ES8609229A1 (pt)
GR (1) GR852496B (pt)
HU (1) HU195479B (pt)
IL (1) IL76707A0 (pt)
NZ (1) NZ213812A (pt)
PT (1) PT81299B (pt)
SU (1) SU1424730A3 (pt)
ZA (1) ZA857871B (pt)

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* Cited by examiner, † Cited by third party
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US5155268A (en) * 1984-05-04 1992-10-13 The Upjohn Company Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides
GB8609630D0 (en) * 1986-04-19 1986-05-21 Pfizer Ltd Anti-arrhythmia agents
EG18188A (en) * 1986-05-01 1992-09-30 Pfizer Ltd Process for preparation anti-arhythmia agents
GB8706662D0 (en) * 1987-03-20 1987-04-23 Pfizer Ltd Anti-arrhythmia agents
DE3732094A1 (de) * 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
US4906634A (en) * 1988-03-08 1990-03-06 Schering A.G. Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents
CA1337128C (en) * 1988-04-08 1995-09-26 David Wayne Robertson Propanamine derivatives
US5238959A (en) * 1988-04-08 1993-08-24 Eli Lilly And Company 3-phenyloxy-3-phenyl propanamines
US5405997A (en) * 1989-07-25 1995-04-11 The Upjohn Company Antiarrhythmic methanesulfonamides
JPH10505829A (ja) * 1994-09-12 1998-06-09 ファルマシア・アンド・アップジョン・カンパニー 抗不整脈活性を有する4−(4−メタンスルホンアミドフェニル)ブチルアミン誘導体
US5874475A (en) * 1995-12-21 1999-02-23 Pharmacia & Upjohn Company Antiarrhythmic (S)-enantiomers of methanesulfonamides
US6012457A (en) 1997-07-08 2000-01-11 The Regents Of The University Of California Device and method for forming a circumferential conduction block in a pulmonary vein
US5971983A (en) * 1997-05-09 1999-10-26 The Regents Of The University Of California Tissue ablation device and method of use
US6024740A (en) 1997-07-08 2000-02-15 The Regents Of The University Of California Circumferential ablation device assembly
US6514249B1 (en) 1997-07-08 2003-02-04 Atrionix, Inc. Positioning system and method for orienting an ablation element within a pulmonary vein ostium
US6245064B1 (en) 1997-07-08 2001-06-12 Atrionix, Inc. Circumferential ablation device assembly
US6966908B2 (en) 1997-07-08 2005-11-22 Atrionix, Inc. Tissue ablation device assembly and method for electrically isolating a pulmonary vein ostium from an atrial wall
US6997925B2 (en) * 1997-07-08 2006-02-14 Atrionx, Inc. Tissue ablation device assembly and method for electrically isolating a pulmonary vein ostium from an atrial wall
US6500174B1 (en) 1997-07-08 2002-12-31 Atrionix, Inc. Circumferential ablation device assembly and methods of use and manufacture providing an ablative circumferential band along an expandable member
US6164283A (en) * 1997-07-08 2000-12-26 The Regents Of The University Of California Device and method for forming a circumferential conduction block in a pulmonary vein
US6869431B2 (en) 1997-07-08 2005-03-22 Atrionix, Inc. Medical device with sensor cooperating with expandable member
US6652515B1 (en) 1997-07-08 2003-11-25 Atrionix, Inc. Tissue ablation device assembly and method for electrically isolating a pulmonary vein ostium from an atrial wall
WO2000010557A1 (fr) * 1998-08-25 2000-03-02 Nippon Shinyaku Co.,Ltd. Preparations solides stabilisees
US6607502B1 (en) 1998-11-25 2003-08-19 Atrionix, Inc. Apparatus and method incorporating an ultrasound transducer onto a delivery member
EP3369453B1 (en) 1999-05-11 2020-03-18 Atrionix, Inc. Medical device positioning system including a balloon anchor wire
US6758830B1 (en) * 1999-05-11 2004-07-06 Atrionix, Inc. Catheter positioning system
JP4754148B2 (ja) * 2000-05-16 2011-08-24 アトリオニックス・インコーポレイテッド 超音波トランスデューサを配送部材に組み込む装置および方法
DE60109444T2 (de) 2000-06-13 2006-04-13 Atrionix, Inc., Irwindale Chirurgische ablationssonde zum formen einer ringförmigen läsion
PT1227766E (pt) 2000-09-08 2005-07-29 Atrionix Inc Dispositivo medico que possui um sensor que coopera com um componente expansivel
US6755822B2 (en) 2001-06-01 2004-06-29 Cryocor, Inc. Device and method for the creation of a circumferential cryogenic lesion in a pulmonary vein
US20040106896A1 (en) * 2002-11-29 2004-06-03 The Regents Of The University Of California System and method for forming a non-ablative cardiac conduction block
EP1503819A4 (en) * 2002-05-08 2007-07-25 Univ California SYSTEM AND METHOD FOR PRODUCING A NON-ABSORBENT HEADLINE BLOCK
US6932804B2 (en) 2003-01-21 2005-08-23 The Regents Of The University Of California System and method for forming a non-ablative cardiac conduction block
US6786202B2 (en) * 2002-09-24 2004-09-07 Caterpillar Inc Hydraulic pump circuit
US7317950B2 (en) * 2002-11-16 2008-01-08 The Regents Of The University Of California Cardiac stimulation system with delivery of conductive agent
US7247269B2 (en) * 2003-07-21 2007-07-24 Biosense Webster, Inc. Method for making a spiral array ultrasound transducer
US7670335B2 (en) 2003-07-21 2010-03-02 Biosense Webster, Inc. Ablation device with spiral array ultrasound transducer
AU2004312058B2 (en) * 2003-12-31 2010-12-02 Biosense Webster, Inc. Circumferential ablation device assembly with dual expandable members
US20060270900A1 (en) * 2005-05-26 2006-11-30 Chin Albert K Apparatus and methods for performing ablation
US8932208B2 (en) * 2005-05-26 2015-01-13 Maquet Cardiovascular Llc Apparatus and methods for performing minimally-invasive surgical procedures
US20070185479A1 (en) * 2006-02-06 2007-08-09 Liming Lau Methods and devices for performing ablation and assessing efficacy thereof
US20070225697A1 (en) * 2006-03-23 2007-09-27 Ketan Shroff Apparatus and methods for cardiac ablation
US20080039879A1 (en) * 2006-08-09 2008-02-14 Chin Albert K Devices and methods for atrial appendage exclusion
US8728073B2 (en) 2006-10-10 2014-05-20 Biosense Webster, Inc. Multi-region staged inflation balloon
US8512387B2 (en) * 2007-09-07 2013-08-20 Robert S. Fishel Esophageal cooling system for ablation procedures associated with cardiac arrhythmias
JP2010540160A (ja) 2007-10-05 2010-12-24 マッケ カーディオバスキュラー,エルエルシー 最小限に侵襲的な外科的処置のための装置および方法
US20090209986A1 (en) * 2008-02-15 2009-08-20 Stewart Michael C Devices, Tools and Methods for Atrial Appendage Exclusion

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR152F (pt) * 1962-01-24
US3574741A (en) * 1969-04-14 1971-04-13 Mead Johnson & Co Sulfonamidophenalkylamines
HU173192B (hu) * 1973-08-13 1979-03-28 Fujisawa Pharmaceutical Co Sposob poluchenija novykh proizvodnykh fenilglicina
US4289787A (en) * 1977-12-19 1981-09-15 Eli Lilly And Company Quaternary ammonium antiarrhythmic drugs
US4277501A (en) * 1977-12-19 1981-07-07 Eli Lilly And Company Para-nitrophenylalkylamines and pharmaceutical compositions
DK268579A (da) * 1978-07-03 1980-01-04 Lilly Co Eli Fremgangsmaade til fremstilling af phenetamolaminer
US4336269A (en) * 1979-12-10 1982-06-22 Eli Lilly And Company Para-nitrophenylalkylamines
DE3566886D1 (en) * 1984-05-04 1989-01-26 Upjohn Co N-(aminoalkylphenyl)sulfonamides their preparation and therapeutic use

Also Published As

Publication number Publication date
EP0178874B1 (en) 1989-04-05
US4569801A (en) 1986-02-11
HUT38610A (en) 1986-06-30
ZA857871B (en) 1987-05-27
CN85107020A (zh) 1986-04-10
JPS6197256A (ja) 1986-05-15
AU4855885A (en) 1986-04-24
DK164450B (da) 1992-06-29
KR880001008B1 (ko) 1988-06-13
ATE41922T1 (de) 1989-04-15
NZ213812A (en) 1989-01-06
AU586644B2 (en) 1989-07-20
DK468185D0 (da) 1985-10-14
AR241528A1 (es) 1992-08-31
CA1291165C (en) 1991-10-22
DK164450C (da) 1992-11-16
ES8609229A1 (es) 1986-09-01
SU1424730A3 (ru) 1988-09-15
EP0178874A1 (en) 1986-04-23
KR860003210A (ko) 1986-05-21
IL76707A0 (en) 1986-02-28
DK468185A (da) 1986-04-16
CN1004133B (zh) 1989-05-10
PT81299B (pt) 1988-02-17
ES547840A0 (es) 1986-09-01
HU195479B (en) 1988-05-30
GR852496B (pt) 1986-02-18

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Legal Events

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Effective date: 19940228