PT804584E - Sequencias de virus da hepatite c genotipo 7 e sua utilizacao como agentes profilacticos terapeuticos e de diagnostico - Google Patents
Sequencias de virus da hepatite c genotipo 7 e sua utilizacao como agentes profilacticos terapeuticos e de diagnosticoInfo
- Publication number
- PT804584E PT804584E PT95936537T PT95936537T PT804584E PT 804584 E PT804584 E PT 804584E PT 95936537 T PT95936537 T PT 95936537T PT 95936537 T PT95936537 T PT 95936537T PT 804584 E PT804584 E PT 804584E
- Authority
- PT
- Portugal
- Prior art keywords
- sequences
- therapeutic
- genotype
- hepatitis
- proprietary
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 241000700605 Viruses Species 0.000 title 1
- 239000000032 diagnostic agent Substances 0.000 title 1
- 229940039227 diagnostic agent Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 208000006454 hepatitis Diseases 0.000 title 1
- 231100000283 hepatitis Toxicity 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP94870166 | 1994-10-21 | ||
EP95870076 | 1995-06-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT804584E true PT804584E (pt) | 2002-11-29 |
Family
ID=26137782
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT95936537T PT804584E (pt) | 1994-10-21 | 1995-10-23 | Sequencias de virus da hepatite c genotipo 7 e sua utilizacao como agentes profilacticos terapeuticos e de diagnostico |
Country Status (12)
Country | Link |
---|---|
US (2) | US7129337B1 (pt) |
EP (2) | EP0804584B2 (pt) |
JP (2) | JPH10507643A (pt) |
AT (1) | ATE218617T1 (pt) |
AU (1) | AU702436B2 (pt) |
BR (1) | BR9509421A (pt) |
CA (1) | CA2201703A1 (pt) |
DE (1) | DE69526973T3 (pt) |
DK (1) | DK0804584T3 (pt) |
ES (1) | ES2176342T5 (pt) |
PT (1) | PT804584E (pt) |
WO (1) | WO1996013590A2 (pt) |
Families Citing this family (57)
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GB9620075D0 (en) * | 1996-09-26 | 1996-11-13 | Dynal As | Method |
US7078500B1 (en) * | 1998-01-30 | 2006-07-18 | The General Hospital Corporation | Genetic immunization with nonstructural proteins of hepatitis C virus |
AU751362B2 (en) | 1998-04-17 | 2002-08-15 | Innogenetics N.V. | Improved immunodiagnostic assays using reducing agents |
WO1999055385A2 (de) * | 1998-04-28 | 1999-11-04 | Wolfgang Bergter | Radioimmunpharmaka zur therapie der hepatitis c |
DK1090033T4 (da) * | 1998-06-24 | 2008-03-31 | Innogenetics Nv | Partikler af HCV-kappeproteiner: Anvendelse til vaccination |
US6680059B2 (en) * | 2000-08-29 | 2004-01-20 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
US7022830B2 (en) | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
ATE375804T1 (de) * | 2000-08-17 | 2007-11-15 | Tripep Ab | Ribavirin-enthaltende vakzine |
US6858590B2 (en) | 2000-08-17 | 2005-02-22 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
US7101561B2 (en) | 2000-12-01 | 2006-09-05 | Innogenetics N.V. | Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use |
GB0126782D0 (en) * | 2001-11-07 | 2002-01-02 | Medical Res Council | Assay |
US8124747B2 (en) * | 2003-08-29 | 2012-02-28 | Innogenetics | HCV clade and prototype sequences thereof |
CN1977050B (zh) * | 2004-01-07 | 2012-09-05 | 第三次浪潮技术公司 | 丙型肝炎病毒基因型的确定 |
RU2267496C2 (ru) * | 2004-01-15 | 2006-01-10 | Сергей Иванович Черныш | Противоопухолевые и антивирусные пептиды |
CA2618429A1 (en) * | 2005-05-25 | 2007-03-22 | Tripep Ab | A hepatitis c virus non-structural ns3/4a fusion gene |
US20070072211A1 (en) | 2005-06-30 | 2007-03-29 | Roche Molecular Systems, Inc. | Asymmetric PCR coupled with post-PCR characterization for the identification of nucleic acids |
PT2361638E (pt) | 2005-12-12 | 2014-04-17 | Ac Immune Sa | Anticorpos monoclonais específicos beta 1-42 com propriedades terapêuticas |
EP2046833B9 (en) | 2006-07-14 | 2014-02-19 | AC Immune S.A. | Humanized antibody against amyloid beta |
TW201815827A (zh) | 2006-07-14 | 2018-05-01 | 瑞士商Ac免疫公司 | 抗β-類澱粉抗體或其抗原結合片段、其用途及使用方法 |
KR101500017B1 (ko) * | 2006-08-25 | 2015-03-09 | 더 맥파레인 버넷 인스티튜트 포 메디칼 리서치 앤드 퍼블릭 헬스 리미티드 | 재조합 hcv e2 당단백질 |
EP2463389A1 (en) | 2006-10-20 | 2012-06-13 | Innogenetics N.V. | Methodology for analysis of sequence variations within the HCV NS5B genomic region |
WO2008046923A2 (en) | 2006-10-20 | 2008-04-24 | Innogenetics N.V. | Methodology for analysis of sequence variations within the hcv ns3/4a genomic region |
KR101450356B1 (ko) | 2006-11-24 | 2014-10-15 | 에이씨 이뮨 에스.에이. | 알츠하이머와 같은 아밀로이드 또는 아밀로이드-유사 단백질과 관련된 질환의 치료를 위한 n-(메틸)-1h-피라졸-3-아민, n-(메틸)-피리딘-2-아민 및 n-(메틸)-티아졸-2-아민 유도체 |
KR20160017126A (ko) | 2007-06-12 | 2016-02-15 | 에이씨 이뮨 에스.에이. | 모노클로널 항 베타 아밀로이드 항체 |
PE20090766A1 (es) | 2007-06-12 | 2009-07-09 | Ac Immune Sa | Anticuerpo igg1 humanizado |
US20100227314A1 (en) * | 2007-08-09 | 2010-09-09 | Dmitry Alexandrovich Gryadunov | Method of identification of genotype and subtype of hepatitis c virus on a biological microchip |
EP2185195A2 (en) | 2007-08-16 | 2010-05-19 | Tripep Ab | Immunogen platform |
SG178809A1 (en) | 2007-10-05 | 2012-03-29 | Genentech Inc | Use of anti-amyloid beta antibody in ocular diseases |
WO2009130588A2 (en) * | 2008-04-22 | 2009-10-29 | Tripep Ab | Immunogen platform |
EP2311823A1 (en) | 2009-10-15 | 2011-04-20 | AC Immune S.A. | 2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases |
MX337548B (es) | 2010-04-16 | 2016-03-10 | Ac Immune Sa | Nuevos compuestos para tratamiento de enfermedades asociadas con proteinas amiloides o tipo amiloide. |
EP2377860A1 (en) | 2010-04-16 | 2011-10-19 | AC Immune S.A. | Novel compounds for the treatment of diseases associated with amyloid or amyloid-like proteins |
US8962241B2 (en) * | 2010-07-20 | 2015-02-24 | California Institute Of Technology | Triggered molecular geometry based bioimaging probes |
SG187173A1 (en) | 2010-07-30 | 2013-02-28 | Ac Immune Sa | Safe and functional humanized anti beta-amyloid antibody |
WO2012045882A2 (en) | 2010-10-07 | 2012-04-12 | Ac Immune S.A. | Pharmaceutical composition |
TW201223561A (en) | 2010-10-26 | 2012-06-16 | Ac Immune Sa | Preparation of an antigenic construct |
MX354662B (es) | 2011-10-07 | 2018-03-14 | Ac Immune Sa | Anticuerpos fosfoespecificos que reconocen la tau. |
AU2013243861A1 (en) | 2012-04-05 | 2014-10-23 | Ac Immune S.A. | Humanized Tau antibody |
SI2859017T1 (sl) | 2012-06-08 | 2019-05-31 | Sutro Biopharma, Inc. | Protitelesa, ki vsebujejo specifične nenaravne aminokislinske ostanke, postopki njihove priprave in postopki njihove uporabe |
WO2014004639A1 (en) | 2012-06-26 | 2014-01-03 | Sutro Biopharma, Inc. | Modified fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use |
CN102766701B (zh) * | 2012-07-04 | 2016-05-04 | 福州泰普生物科学有限公司 | 丙型肝炎病毒基因分型的试剂盒及方法 |
ES2907763T3 (es) | 2012-08-31 | 2022-04-26 | Sutro Biopharma Inc | Aminoácidos modificados que comprenden un grupo azido |
CA2902910A1 (en) | 2013-03-15 | 2014-09-25 | Ac Immune S.A. | Anti-tau antibodies and methods of use |
WO2014183109A1 (en) * | 2013-05-10 | 2014-11-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Compositions and methods for simultaneous detection of hcv antigen/antibody |
EP3019522B1 (en) | 2013-07-10 | 2017-12-13 | Sutro Biopharma, Inc. | Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use |
WO2015032932A1 (en) | 2013-09-05 | 2015-03-12 | Ab2 Bio Sa | Il-18 binding protein (il-18bp) in inflammatory diseases |
WO2015054658A1 (en) | 2013-10-11 | 2015-04-16 | Sutro Biopharma, Inc. | Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use |
MX2017010919A (es) | 2015-03-05 | 2017-12-07 | Ab2 Bio Sa | Proteina de union il-18 (il-18bp) y anticuerpos en enfermedades inflamatorias. |
EP3472197A1 (en) | 2016-06-15 | 2019-04-24 | Sutro Biopharma, Inc. | Antibodies with engineered ch2 domains, compositions thereof and methods of using the same |
GB201807367D0 (en) | 2018-05-04 | 2018-06-20 | Univ Newcastle | Biomarker |
EP4114852A1 (en) | 2020-03-03 | 2023-01-11 | Sutro Biopharma, Inc. | Antibodies comprising site-specific glutamine tags, methods of their preparation and methods of their use |
US20230173021A1 (en) | 2020-05-06 | 2023-06-08 | Ab2 Bio Sa | IL-18 Binding Protein (IL-18BP) In Respiratory Diseases |
EP3943097A1 (en) | 2020-07-24 | 2022-01-26 | AB2 Bio SA | Car-t cell therapy |
WO2023166206A1 (en) | 2022-03-04 | 2023-09-07 | Ab2 Bio Sa | Il-18 binding protein (il-18bp) in the treatment of vexas |
WO2024006563A1 (en) | 2022-07-01 | 2024-01-04 | Sutro Biopharma, Inc. | Il-12 mutants with reduced toxicity, compositions thereof and methods of using the same |
WO2024044780A1 (en) | 2022-08-26 | 2024-02-29 | Sutro Biopharma, Inc. | Interleukin-18 variants and uses thereof |
WO2024098023A2 (en) | 2022-11-04 | 2024-05-10 | Sutro Biopharma, Inc. | Interferon alpha polypeptides and conjugates |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR0185373B1 (ko) | 1989-03-17 | 1999-05-01 | 로버트 피. 블랙버언 | Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용 |
WO1991004262A1 (en) | 1989-09-15 | 1991-04-04 | National Institute Of Health Of Japan | New hcv isolates |
US5372928A (en) | 1989-09-15 | 1994-12-13 | Chiron Corporation | Hepatitis C virus isolates |
DK298190A (da) | 1989-12-18 | 1991-06-19 | Wellcome Found | Viralt middel |
CA2045326A1 (en) | 1990-06-25 | 1991-12-26 | Hiroto Okayama | Non-a, non-b, hepatitis virus particles |
ATE252154T1 (de) | 1991-05-08 | 2003-11-15 | Chiron Corp | Genomische hcv-sequenzen für diagnostik und therapie |
RO117329B1 (ro) * | 1991-06-24 | 2002-01-30 | Chiron Corp Emeryville | Polipeptide care contin o secventa a virusului hepatitei c |
EP0532167A3 (en) | 1991-08-09 | 1993-03-31 | Immuno Japan Inc. | Non-a, non-b hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems |
JPH06511149A (ja) | 1991-09-13 | 1994-12-15 | カイロン コーポレイション | 免疫反応性c型肝炎ウイルスのポリペプチド組成物 |
JP3688290B2 (ja) | 1991-11-21 | 2005-08-24 | コモン サーヴィシス エージェンシー | C型肝炎ウイルス検査 |
ATE373093T1 (de) * | 1993-04-27 | 2007-09-15 | Innogenetics Nv | Sequenzen der genotype des hepatitis-c-virus sowie ihre verwendung als arzneimitteln und diagnostika |
JPH06319563A (ja) * | 1993-05-13 | 1994-11-22 | Imuno Japan:Kk | C型肝炎ウイルス遺伝子、オリゴヌクレオチド、並びにc型 肝炎ウイルス遺伝子型判定方法 |
US5514539A (en) | 1993-06-29 | 1996-05-07 | The United States Of America As Represented By The Department Of Health And Human Services | Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines |
-
1995
- 1995-10-23 US US08/836,075 patent/US7129337B1/en not_active Expired - Fee Related
- 1995-10-23 DK DK95936537T patent/DK0804584T3/da active
- 1995-10-23 JP JP8514299A patent/JPH10507643A/ja active Pending
- 1995-10-23 AU AU38440/95A patent/AU702436B2/en not_active Ceased
- 1995-10-23 PT PT95936537T patent/PT804584E/pt unknown
- 1995-10-23 EP EP95936537A patent/EP0804584B2/en not_active Expired - Lifetime
- 1995-10-23 BR BR9509421A patent/BR9509421A/pt not_active Application Discontinuation
- 1995-10-23 DE DE69526973T patent/DE69526973T3/de not_active Expired - Lifetime
- 1995-10-23 ES ES95936537T patent/ES2176342T5/es not_active Expired - Lifetime
- 1995-10-23 EP EP00118731A patent/EP1076092A3/en not_active Withdrawn
- 1995-10-23 AT AT95936537T patent/ATE218617T1/de not_active IP Right Cessation
- 1995-10-23 WO PCT/EP1995/004155 patent/WO1996013590A2/en active IP Right Grant
- 1995-10-23 CA CA002201703A patent/CA2201703A1/en not_active Abandoned
-
2001
- 2001-05-09 US US09/851,138 patent/US6974864B2/en not_active Expired - Fee Related
-
2004
- 2004-10-20 JP JP2004305574A patent/JP2005118044A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ES2176342T3 (es) | 2002-12-01 |
WO1996013590A3 (en) | 1996-08-15 |
JP2005118044A (ja) | 2005-05-12 |
EP1076092A2 (en) | 2001-02-14 |
DE69526973D1 (de) | 2002-07-11 |
US20020183508A1 (en) | 2002-12-05 |
EP0804584B2 (en) | 2008-07-09 |
CA2201703A1 (en) | 1996-05-09 |
BR9509421A (pt) | 1997-09-30 |
US6974864B2 (en) | 2005-12-13 |
US7129337B1 (en) | 2006-10-31 |
AU702436B2 (en) | 1999-02-18 |
ES2176342T5 (es) | 2010-02-09 |
DE69526973T3 (de) | 2010-01-07 |
ATE218617T1 (de) | 2002-06-15 |
AU3844095A (en) | 1996-05-23 |
DE69526973T2 (de) | 2003-01-02 |
EP0804584B1 (en) | 2002-06-05 |
JPH10507643A (ja) | 1998-07-28 |
DK0804584T3 (da) | 2002-09-23 |
WO1996013590A2 (en) | 1996-05-09 |
EP0804584A1 (en) | 1997-11-05 |
EP1076092A3 (en) | 2001-03-28 |
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