PT76596B - Process for preparing 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives - Google Patents

Process for preparing 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives

Info

Publication number
PT76596B
PT76596B PT76596A PT7659683A PT76596B PT 76596 B PT76596 B PT 76596B PT 76596 A PT76596 A PT 76596A PT 7659683 A PT7659683 A PT 7659683A PT 76596 B PT76596 B PT 76596B
Authority
PT
Portugal
Prior art keywords
azanaphthyridine
naphthyridine
derivatives
preparing
azanaphthyridine derivatives
Prior art date
Application number
PT76596A
Other languages
English (en)
Other versions
PT76596A (en
Inventor
Margaret H Sherlock
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/371,623 external-priority patent/US4452800A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of PT76596A publication Critical patent/PT76596A/pt
Publication of PT76596B publication Critical patent/PT76596B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT76596A 1982-04-26 1983-04-26 Process for preparing 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives PT76596B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/371,623 US4452800A (en) 1982-04-26 1982-04-26 Salts of 3(n-butyl)-4-hydroxy-1-phenyl-1,8-naphthyridine-2(1H)-one and their use in treating chronic obstructive lung diseases
US43868182A 1982-11-03 1982-11-03

Publications (2)

Publication Number Publication Date
PT76596A PT76596A (en) 1983-05-01
PT76596B true PT76596B (en) 1986-02-27

Family

ID=27005451

Family Applications (1)

Application Number Title Priority Date Filing Date
PT76596A PT76596B (en) 1982-04-26 1983-04-26 Process for preparing 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives

Country Status (13)

Country Link
US (1) US4492702A (pt)
EP (1) EP0092786B1 (pt)
AU (1) AU553958B2 (pt)
CA (1) CA1198109A (pt)
DE (1) DE3368929D1 (pt)
DK (1) DK181983A (pt)
HK (1) HK20590A (pt)
IE (1) IE55113B1 (pt)
IL (1) IL68487A0 (pt)
NZ (1) NZ204004A (pt)
PH (1) PH21641A (pt)
PT (1) PT76596B (pt)
SG (1) SG76889G (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4628055A (en) * 1982-11-03 1986-12-09 Schering Corporation Method for treating allergic reactions and compositions therefore
US4680298A (en) * 1983-05-31 1987-07-14 Schering Corporation Tricyclic anti-allergy and use as anti-inflammatory agents
EP0144996B1 (en) * 1983-12-14 1990-02-28 Schering Corporation Substituted spiro pyridine derivatives, pharmaceutical compositions containing them and processes for the preparation of such compounds and compositions
US4632923A (en) * 1984-08-15 1986-12-30 Schering Corporation Substituted hetero spiro pyridine derivatives as anti-allergy and anti-inflammatory agents
FR2567520B1 (fr) * 1984-07-11 1987-01-02 Carpibem Nouvelles phenyl-naphthyridines, leur procede de preparation, medicaments les contenant, notamment anti-ulceres
DK127086A (da) * 1985-03-25 1986-09-26 Schering Corp Substituerede 1,8-naphthyridoner, fremgangsmaader til deres fremstilling og farmaceutiske kompositioner, der indeholder disse forbindelser
DE3669656D1 (de) * 1985-06-18 1990-04-26 Schering Corp Azanaphthalene enthaltende arzneimittelzusammensetzungen.
US4684727A (en) * 1985-07-29 1987-08-04 Schering Corporation Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents
US5011860A (en) * 1986-04-11 1991-04-30 Schering Corporation Aryl-substituted naphthyridine and pyridopyrazine derivatives and their use in treating hyperproliferative skin diseases
US4760073A (en) * 1986-04-11 1988-07-26 Schering Corporation Aryl-substituted naphthyridine and pyridopyrazine derivatives, useful as anti-allergic agents
US4917896A (en) * 1986-08-15 1990-04-17 Nelson Research & Development Co. Penetration enhancers for transdermal delivery of systemic agents
US4916131A (en) * 1986-10-15 1990-04-10 Schering Corporation Naphthyridine derivatives and method for treating allergic reactions
US5037826A (en) * 1986-10-15 1991-08-06 Schering Corporation 1-substituted naphthyridine and pyridopyrazine derivatives
EP0267691A3 (en) * 1986-10-15 1989-08-23 Schering Corporation Use of 1-substituted naphthyridine and pyridopyrazine derivatives for the preparation of medicaments with immunosuppressor activity.
US4775686A (en) * 1986-10-15 1988-10-04 Schering Corporation Naphthyridine derivatives and method for treating allergic reactions
US5045542A (en) * 1986-10-20 1991-09-03 Schering Corporation Immune suppression method employing aryl-substituted naphthyridine and pyridopyrazine derivatives
CA1305478C (en) * 1986-11-06 1992-07-21 Margaret H. Sherlock Naphthyridine and pyridopyrazine compounds and pharmaceutical usage thereof
US4897487A (en) * 1988-04-06 1990-01-30 Schering Corporation Process for preparing intermediates for pharmaceutically useful bicyclic compounds
WO1989000571A2 (en) * 1987-07-22 1989-01-26 Schering Corporation Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation
US4859669A (en) * 1987-12-23 1989-08-22 Schering Corporation Antiinflammatory and anti-hyperproliferative naphthyridin-4-ones
US5079360A (en) * 1988-04-06 1992-01-07 Schering Corporation Processes for preparing bicyclic compounds and intermediates thereof
US5180823A (en) * 1988-04-06 1993-01-19 Schering Corporation Processes for preparing bicyclic compounds
US4996212A (en) * 1989-12-21 1991-02-26 Schering Corporation Antiinflammatory and anti-hyperproliferative compounds
JP2988739B2 (ja) * 1990-04-16 1999-12-13 協和醗酵工業株式会社 １，８−ナフチリジン−２−オン誘導体
NZ291507A (en) * 1994-08-29 1997-12-19 Yamanouchi Pharma Co Ltd 1,8-naphthyridine derivatives; medicaments
WO2001042244A1 (fr) * 1999-12-08 2001-06-14 Grelan Pharmaceutical Co., Ltd. Nouveaux derives 1,8-naphtyridin-2(1h)-one
EP1397359B1 (en) * 2001-05-24 2005-08-31 Merck Frosst Canada & Co. 1-biaryl-1,8-napthyridin-4-one phosphodiesterase-4 inhibitors
GB0614471D0 (en) 2006-07-20 2006-08-30 Syngenta Ltd Herbicidal Compounds
AU2009309837A1 (en) * 2008-10-29 2010-05-06 Basf Se Substituted pyridines having a herbicidal effect

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5854152B2 (ja) * 1976-03-25 1983-12-02 久光製薬株式会社 新規なナフチリジン誘導体
US4128649A (en) * 1977-06-29 1978-12-05 Sandoz, Inc. 4-Hydroxy-pyrido[2,3-b]pyridine-2(1H)-one-3-carboxylic acids and esters
JP3774543B2 (ja) * 1997-06-17 2006-05-17 株式会社日立製作所 立軸ポンプおよびその駆動装置

Also Published As

Publication number Publication date
DK181983D0 (da) 1983-04-25
PH21641A (en) 1988-01-13
IE55113B1 (en) 1990-06-06
DK181983A (da) 1983-10-27
AU1392783A (en) 1983-11-03
CA1198109A (en) 1985-12-17
US4492702A (en) 1985-01-08
SG76889G (en) 1990-04-20
IE830934L (en) 1983-10-26
HK20590A (en) 1990-03-23
EP0092786A2 (en) 1983-11-02
PT76596A (en) 1983-05-01
DE3368929D1 (de) 1987-02-12
AU553958B2 (en) 1986-07-31
NZ204004A (en) 1986-03-14
EP0092786A3 (en) 1984-07-25
EP0092786B1 (en) 1987-01-07
IL68487A0 (en) 1983-07-31

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