PT759942E - Receptor de interleucina-15 - Google Patents
Receptor de interleucina-15Info
- Publication number
- PT759942E PT759942E PT95918389T PT95918389T PT759942E PT 759942 E PT759942 E PT 759942E PT 95918389 T PT95918389 T PT 95918389T PT 95918389 T PT95918389 T PT 95918389T PT 759942 E PT759942 E PT 759942E
- Authority
- PT
- Portugal
- Prior art keywords
- receptor
- interleucina
- disclosed
- interleukin
- dnas
- Prior art date
Links
- 102000004556 Interleukin-15 Receptors Human genes 0.000 abstract 5
- 108010017535 Interleukin-15 Receptors Proteins 0.000 abstract 5
- 238000004113 cell culture Methods 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23691994A | 1994-05-06 | 1994-05-06 | |
| US08/300,903 US5591630A (en) | 1994-05-06 | 1994-09-06 | Monoclonal antibodies that bind interleukin-15 receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT759942E true PT759942E (pt) | 2003-07-31 |
Family
ID=26930223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT95918389T PT759942E (pt) | 1994-05-06 | 1995-05-04 | Receptor de interleucina-15 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5591630A (pt) |
| EP (1) | EP0759942B1 (pt) |
| AT (1) | ATE233788T1 (pt) |
| AU (1) | AU695798B2 (pt) |
| CA (1) | CA2188279C (pt) |
| DE (1) | DE69529822T2 (pt) |
| DK (1) | DK0759942T3 (pt) |
| ES (1) | ES2193192T3 (pt) |
| NZ (1) | NZ285292A (pt) |
| PT (1) | PT759942E (pt) |
| WO (1) | WO1995030695A1 (pt) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6548065B1 (en) * | 1994-05-06 | 2003-04-15 | Immunex Corporation | Interleukin-15 receptors |
| US5795966A (en) * | 1995-02-22 | 1998-08-18 | Immunex Corp | Antagonists of interleukin-15 |
| WO1998016254A1 (en) * | 1996-10-17 | 1998-04-23 | Immunomedics, Inc. | Non-antigenic toxin-conjugate and fusion protein of internalizing receptor system |
| DE69810091T2 (de) * | 1997-02-21 | 2003-10-09 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw., Zwijnaarde | Verwendung von interleukin-15 |
| US20030013668A1 (en) * | 1998-07-07 | 2003-01-16 | Dange Veerapanane Ph.D | Antisense oligonucleotides targeted to il-15 |
| CA2401979A1 (en) * | 2000-03-03 | 2001-09-13 | University Of Utah Research Foundation | Mass1 gene, a target for anticonvulsant drug development |
| US7329405B2 (en) * | 2001-08-23 | 2008-02-12 | Genmab A/S | Human antibodies specific for interleukin 15 (IL-15) |
| HU229776B1 (hu) * | 2001-08-23 | 2014-07-28 | Genmab As | Interleukin 15-re (IL-15-re) specifikus emberi antitestek |
| US7247304B2 (en) * | 2001-08-23 | 2007-07-24 | Genmab A/S | Methods of treating using anti-IL-15 antibodies |
| PL3263581T3 (pl) | 2005-05-17 | 2021-05-04 | University Of Connecticut | Kompozycje i sposoby immunomodulacji w organizmie |
| EP1777294A1 (en) | 2005-10-20 | 2007-04-25 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | IL-15Ralpha sushi domain as a selective and potent enhancer of IL-15 action through IL-15Rbeta/gamma, and hyperagonist (IL15Ralpha sushi -IL15) fusion proteins |
| AU2007207785B2 (en) | 2006-01-13 | 2013-11-14 | The Government Of The United States, As Represented By The Secretary Of The Department Of Health And Human Services, National Institutes Of Health | Codon optimized IL- 15 and IL- 15R-alpha genes for expression in mammalian cells |
| NZ599338A (en) | 2007-06-27 | 2013-11-29 | Marinepolymer Tech Inc | Complexes of il-15 and il-15ralpha and uses thereof |
| AU2010282280B2 (en) | 2009-08-14 | 2016-06-09 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of IL-15 to increase thymic output and to treat lymphopenia |
| WO2011031986A1 (en) | 2009-09-10 | 2011-03-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institutes Of Health | Assays for soluble il-15 receptor alpha |
| NZ630790A (en) | 2012-10-24 | 2016-11-25 | Admune Therapeutics Llc | Il-15r alpha forms, cells expressing il-15r alpha forms, and therapeutic uses of il-15r alpha and il-15/il-15r alpha complexes |
| KR20150145260A (ko) | 2013-04-19 | 2015-12-29 | 싸이튠 파마 | 감소된 혈관 누출 증후근에 대한 사이토카인 유도체 치료 |
| EP3174974B1 (en) | 2014-07-29 | 2020-05-20 | Novartis AG | Il-15 and il-15ralpha heterodimer dose escalation regimens for treating conditions |
| EP3468581A1 (en) | 2016-06-13 | 2019-04-17 | Torque Therapeutics, Inc. | Methods and compositions for promoting immune cell function |
| JP7285828B2 (ja) | 2017-09-05 | 2023-06-02 | トルク セラピューティクス， インコーポレイテッド | 治療用タンパク質組成物ならびにその作製および使用方法 |
| CN112795543B (zh) * | 2021-02-04 | 2022-09-27 | 华中农业大学 | 杂交瘤细胞株及其分泌的抗草鱼IL-15Rα单克隆抗体和应用 |
| WO2024040132A2 (en) | 2022-08-16 | 2024-02-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic | Synergistic interactions for improved cancer treatment |
-
1994
- 1994-09-06 US US08/300,903 patent/US5591630A/en not_active Expired - Lifetime
-
1995
- 1995-05-04 ES ES95918389T patent/ES2193192T3/es not_active Expired - Lifetime
- 1995-05-04 CA CA2188279A patent/CA2188279C/en not_active Expired - Fee Related
- 1995-05-04 DE DE69529822T patent/DE69529822T2/de not_active Expired - Lifetime
- 1995-05-04 NZ NZ285292A patent/NZ285292A/en not_active IP Right Cessation
- 1995-05-04 AU AU24344/95A patent/AU695798B2/en not_active Ceased
- 1995-05-04 AT AT95918389T patent/ATE233788T1/de active
- 1995-05-04 WO PCT/US1995/005585 patent/WO1995030695A1/en active IP Right Grant
- 1995-05-04 EP EP95918389A patent/EP0759942B1/en not_active Expired - Lifetime
- 1995-05-04 PT PT95918389T patent/PT759942E/pt unknown
- 1995-05-04 DK DK95918389T patent/DK0759942T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| US5591630A (en) | 1997-01-07 |
| CA2188279A1 (en) | 1995-11-16 |
| DE69529822T2 (de) | 2003-12-11 |
| EP0759942B1 (en) | 2003-03-05 |
| EP0759942A1 (en) | 1997-03-05 |
| WO1995030695A1 (en) | 1995-11-16 |
| CA2188279C (en) | 2010-01-26 |
| DK0759942T3 (da) | 2003-06-10 |
| NZ285292A (en) | 1998-08-26 |
| EP0759942A4 (en) | 1999-05-12 |
| ATE233788T1 (de) | 2003-03-15 |
| AU695798B2 (en) | 1998-08-20 |
| AU2434495A (en) | 1995-11-29 |
| ES2193192T3 (es) | 2003-11-01 |
| DE69529822D1 (de) | 2003-04-10 |
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