PT75822B - Process for preparing n-(2,6-dichlorophenyl)-acetamidine and of pharmaceutical compositions containing the same - Google Patents

Process for preparing n-(2,6-dichlorophenyl)-acetamidine and of pharmaceutical compositions containing the same

Info

Publication number
PT75822B
PT75822B PT75822A PT7582282A PT75822B PT 75822 B PT75822 B PT 75822B PT 75822 A PT75822 A PT 75822A PT 7582282 A PT7582282 A PT 7582282A PT 75822 B PT75822 B PT 75822B
Authority
PT
Portugal
Prior art keywords
acetamidine
dichlorophenyl
preparing
same
pharmaceutical compositions
Prior art date
Application number
PT75822A
Other languages
English (en)
Other versions
PT75822A (en
Inventor
Leonardo De Vincentiis
Original Assignee
Ausonia Farma Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ausonia Farma Srl filed Critical Ausonia Farma Srl
Publication of PT75822A publication Critical patent/PT75822A/pt
Publication of PT75822B publication Critical patent/PT75822B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
PT75822A 1981-12-01 1982-11-10 Process for preparing n-(2,6-dichlorophenyl)-acetamidine and of pharmaceutical compositions containing the same PT75822B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8125374A IT1211138B (it) 1981-12-01 1981-12-01 Composto antiipertensivo procedimento per la sua preparazione e relative composizioni farmaceutiche.

Publications (2)

Publication Number Publication Date
PT75822A PT75822A (en) 1982-12-01
PT75822B true PT75822B (en) 1986-01-15

Family

ID=11216504

Family Applications (1)

Application Number Title Priority Date Filing Date
PT75822A PT75822B (en) 1981-12-01 1982-11-10 Process for preparing n-(2,6-dichlorophenyl)-acetamidine and of pharmaceutical compositions containing the same

Country Status (11)

Country Link
US (1) US4503076A (pt)
EP (1) EP0080592B1 (pt)
JP (1) JPS58109463A (pt)
KR (1) KR860000999B1 (pt)
AT (1) ATE11669T1 (pt)
AU (1) AU536365B2 (pt)
DE (1) DE3262231D1 (pt)
ES (1) ES510653A0 (pt)
IT (1) IT1211138B (pt)
PT (1) PT75822B (pt)
ZA (1) ZA828237B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE231126T1 (de) * 1993-08-12 2003-02-15 Astrazeneca Ab Amidin-derivate mit stickstoffoxid-synthease- aktivität
TW201240602A (en) 2011-03-09 2012-10-16 Du Pont Herbicidal bis-nitrogen-containing oxo heterocycles

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3206468A (en) * 1963-11-15 1965-09-14 Merck & Co Inc Methods of preparing benzimidazoles
US3754093A (en) * 1970-04-28 1973-08-21 Ishihara Mining & Chemical Co Method for protecting plants from powdery mildew fungus and fungicidal composition to be used therefor
DE2831671A1 (de) * 1978-07-19 1980-02-07 Boehringer Sohn Ingelheim Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben

Also Published As

Publication number Publication date
ES8307712A1 (es) 1983-07-16
PT75822A (en) 1982-12-01
JPS58109463A (ja) 1983-06-29
ZA828237B (en) 1983-08-31
EP0080592B1 (en) 1985-02-06
AU536365B2 (en) 1984-05-03
KR840002347A (ko) 1984-06-25
JPS6110461B2 (pt) 1986-03-29
EP0080592A1 (en) 1983-06-08
KR860000999B1 (ko) 1986-07-26
IT1211138B (it) 1989-09-29
IT8125374A0 (it) 1981-12-01
DE3262231D1 (en) 1985-03-21
US4503076A (en) 1985-03-05
AU9022782A (en) 1983-06-09
ES510653A0 (es) 1983-07-16
ATE11669T1 (de) 1985-02-15

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