PT74283A - Process for preparing hexahydro-trans- and tetrahydropyridoin- dole neuroleptic agents - Google Patents

Process for preparing hexahydro-trans- and tetrahydropyridoin- dole neuroleptic agents

Info

Publication number
PT74283A
PT74283A PT74283A PT7428382A PT74283A PT 74283 A PT74283 A PT 74283A PT 74283 A PT74283 A PT 74283A PT 7428382 A PT7428382 A PT 7428382A PT 74283 A PT74283 A PT 74283A
Authority
PT
Portugal
Prior art keywords
tetrahydropyridoin
dole
trans
neuroleptic agents
hexahydro
Prior art date
Application number
PT74283A
Other languages
English (en)
Inventor
Willard Mckowan Welch
Charles Armon Harbert
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT74283A publication Critical patent/PT74283A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT74283A 1981-01-16 1982-01-15 Process for preparing hexahydro-trans- and tetrahydropyridoin- dole neuroleptic agents PT74283A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/225,569 US4337250A (en) 1979-07-30 1981-01-16 Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents

Publications (1)

Publication Number Publication Date
PT74283A true PT74283A (pt) 1982-02-01

Family

ID=22845384

Family Applications (1)

Application Number Title Priority Date Filing Date
PT74283A PT74283A (pt) 1981-01-16 1982-01-15 Process for preparing hexahydro-trans- and tetrahydropyridoin- dole neuroleptic agents

Country Status (27)

Country Link
US (1) US4337250A (pt)
EP (1) EP0060610B1 (pt)
JP (2) JPS57139078A (pt)
KR (1) KR860001819B1 (pt)
AR (1) AR230283A1 (pt)
AT (1) ATE15372T1 (pt)
AU (1) AU528710B2 (pt)
CA (1) CA1177830A (pt)
CS (1) CS248020B2 (pt)
DD (3) DD208980A5 (pt)
DE (1) DE3265922D1 (pt)
DK (1) DK15282A (pt)
EG (1) EG15796A (pt)
ES (11) ES8304966A1 (pt)
FI (1) FI71936C (pt)
GR (1) GR74757B (pt)
HU (1) HU189090B (pt)
IE (1) IE51954B1 (pt)
IL (1) IL64774A (pt)
NO (1) NO159090C (pt)
NZ (1) NZ199473A (pt)
PH (1) PH19614A (pt)
PL (2) PL137682B1 (pt)
PT (1) PT74283A (pt)
SU (2) SU1179930A3 (pt)
YU (1) YU45854B (pt)
ZA (1) ZA82264B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4672117A (en) * 1985-09-16 1987-06-09 American Home Products Corporation Antipsychotic gamma-carbolines
US4636563A (en) * 1985-09-16 1987-01-13 American Home Products Corporation Antipsychotic γ-carbolines
US4732984A (en) * 1985-10-17 1988-03-22 American Home Products Corporation Piperazinoisothiazolones with psychotropic activity
US4748182A (en) * 1986-03-05 1988-05-31 Merrell Dow Pharmaceuticals Inc. Aromatic 2-aminoalkyl-1,2-benzoisothiazol-3(2H)one-1,1-dioxide derivatives and their use as anti-hypertensive and anxiolytic agents
JPH01140486A (ja) * 1987-11-27 1989-06-01 Hitachi Ltd ブロッホラインメモリ駆動回路
FR2661177A1 (fr) * 1990-04-23 1991-10-25 Rhone Poulenc Sante Derives du naphtosultame antagonistes de la serotonine, leur preparation et les medicaments les contenant.
TW470745B (en) * 1996-05-23 2002-01-01 Janssen Pharmaceutica Nv Hexahydro-pyrido[4,3-b]indole derivatives
US5879444A (en) * 1997-09-02 1999-03-09 Bayer Corporation Organic pigment compositions
CA2453537A1 (en) * 2001-08-08 2003-02-20 Pharmacia & Upjohn Company Therapeutic 1h-pyrido¬4,3-b|indoles
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3687961A (en) * 1971-05-03 1972-08-29 Abbott Lab 8-fluoro-2-{8 3-(4-fluorophenylanilinopropyl{9 -gamma-carboline
AR205452A1 (es) * 1973-12-06 1976-05-07 Endo Lab Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles
JPS50126699A (pt) * 1974-03-20 1975-10-04
US4001263A (en) * 1974-04-01 1977-01-04 Pfizer Inc. 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines
SE7702301L (sv) * 1976-04-08 1977-10-09 Endo Lab Trans-hexahydro-pyrido-indoler
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4252811A (en) * 1979-07-30 1981-02-24 Pfizer Inc. Hexahydro-trans-pyridoindole neuroleptic agents

Also Published As

Publication number Publication date
DE3265922D1 (en) 1985-10-10
ES518294A0 (es) 1984-05-16
DD208980A5 (de) 1984-04-18
ES518296A0 (es) 1984-01-01
ES518288A0 (es) 1984-01-01
AR230283A1 (es) 1984-03-01
PL235180A1 (en) 1983-11-21
IL64774A0 (en) 1982-03-31
US4337250A (en) 1982-06-29
GR74757B (pt) 1984-07-11
FI820138L (fi) 1982-07-17
ES518297A0 (es) 1984-06-01
ES8405617A1 (es) 1984-06-16
YU9882A (en) 1986-04-30
NO159090C (no) 1988-11-30
ES8405003A1 (es) 1984-05-16
KR860001819B1 (ko) 1986-10-24
EG15796A (en) 1986-12-30
JPS60185780A (ja) 1985-09-21
DK15282A (da) 1982-08-27
JPS6130674B2 (pt) 1986-07-15
ES8405002A1 (es) 1984-05-16
KR830009095A (ko) 1983-12-17
ATE15372T1 (de) 1985-09-15
PL138924B1 (en) 1986-11-29
IE820061L (en) 1982-07-16
NO159090B (no) 1988-08-22
ES518293A0 (es) 1984-06-16
NZ199473A (en) 1985-10-11
ES518289A0 (es) 1984-05-16
FI71936C (fi) 1987-03-09
FI71936B (fi) 1986-11-28
DD211348A5 (de) 1984-07-11
ES8401963A1 (es) 1984-01-01
ES8404851A1 (es) 1984-05-16
CS248020B2 (en) 1987-01-15
ES518292A0 (es) 1984-01-01
IE51954B1 (en) 1987-04-29
PL137682B1 (en) 1986-07-31
EP0060610B1 (en) 1985-09-04
CA1177830A (en) 1984-11-13
IL64774A (en) 1985-06-30
ZA82264B (en) 1982-12-29
ES508809A0 (es) 1983-03-16
SU1152522A3 (en) 1985-04-23
ES8405391A1 (es) 1984-06-01
ES518290A0 (es) 1984-05-16
ES518295A0 (es) 1984-01-01
ES8304966A1 (es) 1983-03-16
ES8401965A1 (es) 1984-01-01
PH19614A (en) 1986-05-30
DD222027A5 (de) 1985-05-08
ES8401962A1 (es) 1984-01-01
JPS57139078A (en) 1982-08-27
PL241179A1 (en) 1984-03-26
HU189090B (en) 1986-06-30
NO820112L (no) 1982-07-19
ES8405785A1 (es) 1984-06-16
ES518291A0 (es) 1984-06-16
EP0060610A1 (en) 1982-09-22
YU45854B (sh) 1992-09-07
ES8401964A1 (es) 1984-01-01
SU1179930A3 (ru) 1985-09-15
AU528710B2 (en) 1983-05-12
AU7955282A (en) 1982-07-22

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