PT73388B - Process for preparing antiinflammatory 4,5-diaryl-alfa-poly- fluoroalkyl-1h-imidazole-2-methanamides and pharmaceutical compositions containing the same - Google Patents
Process for preparing antiinflammatory 4,5-diaryl-alfa-poly- fluoroalkyl-1h-imidazole-2-methanamides and pharmaceutical compositions containing the sameInfo
- Publication number
- PT73388B PT73388B PT73388A PT7338881A PT73388B PT 73388 B PT73388 B PT 73388B PT 73388 A PT73388 A PT 73388A PT 7338881 A PT7338881 A PT 7338881A PT 73388 B PT73388 B PT 73388B
- Authority
- PT
- Portugal
- Prior art keywords
- methanamides
- alfa
- diaryl
- fluoroalkyl
- imidazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17087180A | 1980-07-21 | 1980-07-21 | |
| US06/271,276 US4348404A (en) | 1980-07-21 | 1981-06-15 | Antiinflammatory 4,5-diaryl-α-polyfluoroalkyl-1H-imidazole-2-methanamines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT73388A PT73388A (en) | 1981-08-01 |
| PT73388B true PT73388B (en) | 1983-09-14 |
Family
ID=26866505
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT73388A PT73388B (en) | 1980-07-21 | 1981-07-17 | Process for preparing antiinflammatory 4,5-diaryl-alfa-poly- fluoroalkyl-1h-imidazole-2-methanamides and pharmaceutical compositions containing the same |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4348404A (pt) |
| EP (1) | EP0044486B1 (pt) |
| AU (1) | AU7312581A (pt) |
| CA (1) | CA1144552A (pt) |
| DE (1) | DE3166949D1 (pt) |
| DK (1) | DK323981A (pt) |
| ES (1) | ES504121A0 (pt) |
| FI (1) | FI812270L (pt) |
| GR (1) | GR76541B (pt) |
| HU (1) | HU185938B (pt) |
| IL (1) | IL63368A0 (pt) |
| NO (1) | NO812484L (pt) |
| NZ (1) | NZ197762A (pt) |
| PH (1) | PH16513A (pt) |
| PT (1) | PT73388B (pt) |
| YU (1) | YU180181A (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA826501B (en) * | 1982-09-06 | 1984-04-25 | Du Pont | Anti-hypertensive imidazole derivative |
| US4478845A (en) * | 1983-01-19 | 1984-10-23 | E. I. Du Pont De Nemours And Company | Antiinflammatory and/or analgesic imidazoimidazoles |
| US4632930A (en) * | 1984-11-30 | 1986-12-30 | E. I. Du Pont De Nemours And Company | Antihypertensive alkyl-arylimidazole, thiazole and oxazole derivatives |
| NZ238688A (en) * | 1990-06-28 | 1992-05-26 | Smithkline Beecham Corp | Substituted histidines: pharmaceutical compositions, preparation and uses thereof |
| US5620999A (en) * | 1994-07-28 | 1997-04-15 | Weier; Richard M. | Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation |
| US6426360B1 (en) * | 1994-07-28 | 2002-07-30 | G D Searle & Co. | 4,5-substituted imidazolyl compounds for the treatment of inflammation |
| US5700826A (en) * | 1995-06-07 | 1997-12-23 | Ontogen Corporation | 1,2,4,5-tetra substituted imidazoles as modulators of multi-drug resistance |
| KR20010014288A (ko) * | 1997-06-30 | 2001-02-26 | 오르토-맥네일 파마슈티칼, 인코퍼레이티드 | 염증성 질환의 치료에 유용한 2-치환된 이미다졸 |
| US5840721A (en) * | 1997-07-09 | 1998-11-24 | Ontogen Corporation | Imidazole derivatives as MDR modulators |
| JP2002516322A (ja) | 1998-05-22 | 2002-06-04 | スミスクライン・ビーチャム・コーポレイション | 新規２−アルキル置換イミダゾール化合物 |
| TWI283577B (en) * | 1999-10-11 | 2007-07-11 | Sod Conseils Rech Applic | Pharmaceutical composition of imidazole derivatives acting as modulators of sodium channels and the use thereof |
| WO2001037835A1 (en) | 1999-11-22 | 2001-05-31 | Smithkline Beecham Plc. | Novel compounds |
| CN1411449A (zh) * | 1999-12-17 | 2003-04-16 | 宝洁公司 | N－(1－苯乙基)－5－苯基－咪唑－2－胺化合物,它们的组合物和应用 |
| US6596739B2 (en) | 2000-03-29 | 2003-07-22 | The Procter & Gamble Company | N-(1-phenylethyl)-5-phenyl-imidazole-2-amine compounds, their compositions and uses |
| GB0112348D0 (en) * | 2001-05-19 | 2001-07-11 | Smithkline Beecham Plc | Compounds |
| WO2003022837A1 (en) * | 2001-09-05 | 2003-03-20 | Smithkline Beecham P.L.C. | Heterocycle-carboxamide derivatives as raf kinase inhibitors |
| DE60304778T2 (de) | 2002-08-30 | 2006-09-21 | Ishida Co., Ltd. | Display-Streifen |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2532547A (en) * | 1950-12-05 | Z-aminoalkyl-glyoxaline derivatives | ||
| US3197480A (en) * | 1962-12-12 | 1965-07-27 | Du Pont | 2 and 2, 4-(alpha hydroxypolyperhalocycloalkyl)-thiophenes, pyrroles, and furans; 2 and 2, 4-[(alpha hydroxyalpha, alpha dipolyperhalo hydrocarbon) methyl]-thiophenes, pyrroles and furans and process for making them |
| US3707475A (en) * | 1970-11-16 | 1972-12-26 | Pfizer | Antiinflammatory imidazoles |
| US3929807A (en) * | 1971-05-10 | 1975-12-30 | Ciba Geigy Corp | 2-Substituted-4(5)-(aryl)-5(4)-(2,3 or -4-pyridyl)-imidazoles |
| BE793407A (fr) | 1971-12-28 | 1973-06-28 | Hoechst Ag | Imidazolyl - (2) -carbinols ayant une activite hypolipidemique et leur procede de preparation |
| US4190666A (en) * | 1975-08-11 | 1980-02-26 | E. I. Du Pont De Nemours And Company | Anti-inflammatory 4,5-diarly-2-(substituted-thio)imidazoles and their corresponding sulfoxides and sulfones |
| US4159338A (en) * | 1977-02-09 | 1979-06-26 | E. I. Du Pont De Nemours And Company | Antiinflammatory-4,5-dicyclic-2-(substituted thio)-imidazoles and their corresponding sulfoxides and sulfones |
| DE2960506D1 (en) * | 1978-04-24 | 1981-10-29 | Dumex Ltd As | Arylimidazoles, their synthesis and pharmaceutical or veterinary preparations containing them |
| US4199592A (en) * | 1978-08-29 | 1980-04-22 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-2-nitroimidazoles |
-
1981
- 1981-06-15 US US06/271,276 patent/US4348404A/en not_active Expired - Fee Related
- 1981-07-10 DE DE8181105392T patent/DE3166949D1/de not_active Expired
- 1981-07-10 EP EP81105392A patent/EP0044486B1/en not_active Expired
- 1981-07-16 CA CA000381924A patent/CA1144552A/en not_active Expired
- 1981-07-17 PT PT73388A patent/PT73388B/pt unknown
- 1981-07-20 GR GR65568A patent/GR76541B/el unknown
- 1981-07-20 FI FI812270A patent/FI812270L/fi not_active Application Discontinuation
- 1981-07-20 NZ NZ197762A patent/NZ197762A/en unknown
- 1981-07-20 HU HU812114A patent/HU185938B/hu unknown
- 1981-07-20 PH PH25933A patent/PH16513A/en unknown
- 1981-07-20 DK DK323981A patent/DK323981A/da not_active Application Discontinuation
- 1981-07-20 NO NO812484A patent/NO812484L/no unknown
- 1981-07-20 AU AU73125/81A patent/AU7312581A/en not_active Abandoned
- 1981-07-20 ES ES504121A patent/ES504121A0/es active Granted
- 1981-07-20 IL IL63368A patent/IL63368A0/xx unknown
- 1981-07-21 YU YU01801/81A patent/YU180181A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4348404A (en) | 1982-09-07 |
| IL63368A0 (en) | 1981-10-30 |
| GR76541B (pt) | 1984-08-10 |
| FI812270L (fi) | 1982-01-22 |
| ES8301218A1 (es) | 1982-12-01 |
| CA1144552A (en) | 1983-04-12 |
| PT73388A (en) | 1981-08-01 |
| DE3166949D1 (de) | 1984-12-06 |
| DK323981A (da) | 1982-01-22 |
| YU180181A (en) | 1984-02-29 |
| EP0044486A1 (en) | 1982-01-27 |
| NZ197762A (en) | 1984-09-28 |
| NO812484L (no) | 1982-01-22 |
| ES504121A0 (es) | 1982-12-01 |
| EP0044486B1 (en) | 1984-10-31 |
| AU7312581A (en) | 1982-01-28 |
| PH16513A (en) | 1983-11-08 |
| HU185938B (en) | 1985-04-28 |
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