PT73112B - Process for preparing new substituted 3-phenoxy-1-alkoxy-carbonyl-alkylaminopropanol-2-s having beta receptor blocking properties - Google Patents
Process for preparing new substituted 3-phenoxy-1-alkoxy-carbonyl-alkylaminopropanol-2-s having beta receptor blocking propertiesInfo
- Publication number
- PT73112B PT73112B PT73112A PT7311281A PT73112B PT 73112 B PT73112 B PT 73112B PT 73112 A PT73112 A PT 73112A PT 7311281 A PT7311281 A PT 7311281A PT 73112 B PT73112 B PT 73112B
- Authority
- PT
- Portugal
- Prior art keywords
- alkylaminopropanol
- phenoxy
- carbonyl
- alkoxy
- beta receptor
- Prior art date
Links
- 230000000903 blocking effect Effects 0.000 title abstract 2
- 102000012740 beta Adrenergic Receptors Human genes 0.000 title 1
- 108010079452 beta Adrenergic Receptors Proteins 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 206010000891 acute myocardial infarction Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000015005 beta-adrenergic receptor activity proteins Human genes 0.000 abstract 1
- 108040006818 beta-adrenergic receptor activity proteins Proteins 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8004088A SE8004088L (sv) | 1980-06-02 | 1980-06-02 | Nya substituerade 3-fenoxi-l-alkoxikarbonylalkylamino-propanol-2-er med beta-receptorblockerande egenskaper samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma och metod att ... |
Publications (2)
Publication Number | Publication Date |
---|---|
PT73112A PT73112A (en) | 1981-07-01 |
PT73112B true PT73112B (en) | 1983-05-11 |
Family
ID=20341102
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT73112A PT73112B (en) | 1980-06-02 | 1981-06-01 | Process for preparing new substituted 3-phenoxy-1-alkoxy-carbonyl-alkylaminopropanol-2-s having beta receptor blocking properties |
Country Status (24)
Country | Link |
---|---|
US (1) | US5051446A (en, 2012) |
EP (1) | EP0041492B1 (en, 2012) |
JP (1) | JPS5724334A (en, 2012) |
KR (1) | KR850000872B1 (en, 2012) |
AT (1) | ATE12223T1 (en, 2012) |
AU (1) | AU549890B2 (en, 2012) |
CA (1) | CA1167465A (en, 2012) |
CS (1) | CS404681A2 (en, 2012) |
DD (1) | DD159329A5 (en, 2012) |
DE (1) | DE3169348D1 (en, 2012) |
DK (1) | DK152490C (en, 2012) |
ES (1) | ES502654A0 (en, 2012) |
FI (1) | FI73198C (en, 2012) |
GR (1) | GR75683B (en, 2012) |
HU (1) | HU184859B (en, 2012) |
IE (1) | IE52300B1 (en, 2012) |
MY (1) | MY8600651A (en, 2012) |
NO (1) | NO162283C (en, 2012) |
NZ (1) | NZ197238A (en, 2012) |
PH (1) | PH16848A (en, 2012) |
PT (1) | PT73112B (en, 2012) |
SE (1) | SE8004088L (en, 2012) |
SU (1) | SU1082317A3 (en, 2012) |
ZA (1) | ZA812983B (en, 2012) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4593119A (en) * | 1980-11-28 | 1986-06-03 | American Hospital Supply Corporation | Method for treatment or prophylaxis of cardiac disorders |
EP0053434B1 (en) * | 1980-11-28 | 1986-08-27 | American Hospital Supply Corporation | Compounds and method for treatment or prophylaxis of cardiac disorders |
US4559359A (en) * | 1981-06-23 | 1985-12-17 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
US4578403A (en) * | 1981-06-23 | 1986-03-25 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
US4454154A (en) * | 1981-06-23 | 1984-06-12 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
US4455317A (en) * | 1981-06-23 | 1984-06-19 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
CA1211111A (en) * | 1982-02-15 | 1986-09-09 | Isao Yanagisawa | Process for preparing novel pyrimidone compounds |
DE3475615D1 (en) * | 1983-02-03 | 1989-01-19 | Univ California | Beta-adrenergic antagonist compounds and derivatives of beta-adrenergic antagonists |
US4687873A (en) * | 1983-02-03 | 1987-08-18 | The Regents Of The University Of California | Derivatives of β-adrenergic antagonists |
JPS63162660A (ja) * | 1986-12-26 | 1988-07-06 | Toray Ind Inc | 感光性化合物の製造方法 |
US5256812A (en) * | 1989-01-31 | 1993-10-26 | Hoffmann-La Roche Inc. | Carboxamides and sulfonamides |
US5084466A (en) * | 1989-01-31 | 1992-01-28 | Hoffmann-La Roche Inc. | Novel carboxamide pyridine compounds which have useful pharmaceutical utility |
JP3807573B2 (ja) | 1997-11-20 | 2006-08-09 | 住友電気工業株式会社 | ディスクブレーキ用パッド |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB673413A (en) * | 1950-03-22 | 1952-06-04 | Rhone Poulenc Sa | New local anaesthetics which are substituted benzoic esters and processes for making the same |
NL163775C (nl) * | 1967-12-18 | 1980-10-15 | Boehringer Sohn Ingelheim | Werkwijze ter bereiding van farmaceutische preparaten met beta-receptoren blokkerende werking, alsmede werkwijze ter bereiding van 1-(cyaanfenoxy)-2-hydroxy-3-(sec.alkylamino) propaanderivaten. |
DE1922003C3 (de) * | 1969-04-30 | 1979-10-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | N-(3-Aryloxy-2-hydroxypropyl)-aminocarbonsäuren, deren Ester, Amide und Salze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung von Herzinsuffizienz |
SE354851B (en, 2012) * | 1970-02-18 | 1973-03-26 | Haessle Ab | |
FR2132570B1 (en, 2012) * | 1971-04-09 | 1974-08-02 | Lipha | |
DE2324584A1 (de) * | 1972-06-08 | 1974-01-10 | Ciba Geigy Ag | Neue amine und verfahren zu ihrer herstellung |
SE386892B (sv) * | 1972-07-06 | 1976-08-23 | Haessle Ab | Forfarande for framstellning av oxaminoforeningar |
SE388849B (sv) | 1974-02-14 | 1976-10-18 | Haessle Ab | Forfarande for framstellning av nya aminer med beta-receptorstimulerande verkan |
PT66890B (fr) * | 1976-08-21 | 1979-01-25 | Hexachimie | Procede pour la preparation des aryloxy-1 amino-3 propanol-2 |
US4450173A (en) * | 1980-11-28 | 1984-05-22 | American Hospital Supply Corporation | Compounds and method for treatment or prophylaxis of cardiac disorders |
US4387103A (en) * | 1980-11-28 | 1983-06-07 | American Hospital Supply Corporation | Method for treatment or prophylaxis of cardiac disorders |
-
1980
- 1980-06-02 SE SE8004088A patent/SE8004088L/xx not_active Application Discontinuation
-
1981
- 1981-05-05 ZA ZA00812983A patent/ZA812983B/xx unknown
- 1981-05-08 CA CA000377144A patent/CA1167465A/en not_active Expired
- 1981-05-27 DE DE8181850096T patent/DE3169348D1/de not_active Expired
- 1981-05-27 AT AT81850096T patent/ATE12223T1/de not_active IP Right Cessation
- 1981-05-27 NO NO811798A patent/NO162283C/no not_active IP Right Cessation
- 1981-05-27 EP EP81850096A patent/EP0041492B1/en not_active Expired
- 1981-05-28 PH PH25684A patent/PH16848A/en unknown
- 1981-05-29 AU AU71167/81A patent/AU549890B2/en not_active Ceased
- 1981-05-29 IE IE1207/81A patent/IE52300B1/en not_active IP Right Cessation
- 1981-05-29 FI FI811672A patent/FI73198C/fi not_active IP Right Cessation
- 1981-05-29 NZ NZ197238A patent/NZ197238A/en unknown
- 1981-05-30 KR KR1019810001932A patent/KR850000872B1/ko not_active Expired
- 1981-06-01 CS CS814046A patent/CS404681A2/cs unknown
- 1981-06-01 DK DK239481A patent/DK152490C/da active
- 1981-06-01 SU SU813289352A patent/SU1082317A3/ru active
- 1981-06-01 GR GR65115A patent/GR75683B/el unknown
- 1981-06-01 HU HU811623A patent/HU184859B/hu unknown
- 1981-06-01 PT PT73112A patent/PT73112B/pt unknown
- 1981-06-01 DD DD81230465A patent/DD159329A5/de not_active IP Right Cessation
- 1981-06-01 ES ES502654A patent/ES502654A0/es active Granted
- 1981-06-02 JP JP8390481A patent/JPS5724334A/ja active Granted
-
1986
- 1986-12-30 MY MY651/86A patent/MY8600651A/xx unknown
-
1989
- 1989-03-13 US US07/323,194 patent/US5051446A/en not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC3A | Transfer or assignment |
Free format text: 920721 DU PONT MERCK PHARMACEUTICAL COMPANY, THE US |
|
PC3A | Transfer or assignment |
Free format text: 940126 OHMEDA GB |