ES8300085A1 - Un procedimiento para la preparacion de nuevos derivados de 2-propanol - Google Patents

Un procedimiento para la preparacion de nuevos derivados de 2-propanol

Info

Publication number
ES8300085A1
ES8300085A1 ES502654A ES502654A ES8300085A1 ES 8300085 A1 ES8300085 A1 ES 8300085A1 ES 502654 A ES502654 A ES 502654A ES 502654 A ES502654 A ES 502654A ES 8300085 A1 ES8300085 A1 ES 8300085A1
Authority
ES
Spain
Prior art keywords
alkoxycarbonyl
alkylamino
phenoxy
propanol
beta receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES502654A
Other languages
English (en)
Other versions
ES502654A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hassle AB
Original Assignee
Hassle AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hassle AB filed Critical Hassle AB
Publication of ES502654A0 publication Critical patent/ES502654A0/es
Publication of ES8300085A1 publication Critical patent/ES8300085A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVADOS DE 2-PROPANOL. SE HACE REACCIONAR UN COMPUESTO DE FORMULA GENERAL (I) CON LA AMINA H2NX3. SE OBTIENE EL COMPUESTO (II) EL CUAL TIENE OPCIONALMENTE UN RESTO ELIMINABLE EN EL ATOMO DE NITROGENO DEL GRUPO AMINO Y/O TIENE OPCIONALMENTE UN RESTO ELIMINABLE EN LOS GRUPOS HIDROXI. CUANDO APAREZCA EL RESTO ELIMINABLE, EL RESTO X ELEVADO A 2 PRESENTA, ES TRANSFORMADO EN EL COMPUESTO (III) Y SI SE DESEA SE INTRODUCEN SUSTITUYENTES, SE ELIMINAN O SE HACEN REACCIONAR PARA OBTENER EL PRODUCTO FINAL Y/O LAS MEZCLAS OBTENIDAS, SE SEPARAN EN ISOMEROS PUROS Y/O LOS RACEMATOS OBTENIDOS SE SEPARAN EN ANTIPODAS OPTICOS Y/O LAS BASES LIBRES SE TRANSFORMAN EN SUS SALES CORRESPONDIENTES. *FORMULA*.
ES502654A 1980-06-02 1981-06-01 Un procedimiento para la preparacion de nuevos derivados de 2-propanol Expired ES8300085A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8004088A SE8004088L (sv) 1980-06-02 1980-06-02 Nya substituerade 3-fenoxi-l-alkoxikarbonylalkylamino-propanol-2-er med beta-receptorblockerande egenskaper samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma och metod att ...

Publications (2)

Publication Number Publication Date
ES502654A0 ES502654A0 (es) 1982-10-01
ES8300085A1 true ES8300085A1 (es) 1982-10-01

Family

ID=20341102

Family Applications (1)

Application Number Title Priority Date Filing Date
ES502654A Expired ES8300085A1 (es) 1980-06-02 1981-06-01 Un procedimiento para la preparacion de nuevos derivados de 2-propanol

Country Status (24)

Country Link
US (1) US5051446A (es)
EP (1) EP0041492B1 (es)
JP (1) JPS5724334A (es)
KR (1) KR850000872B1 (es)
AT (1) ATE12223T1 (es)
AU (1) AU549890B2 (es)
CA (1) CA1167465A (es)
CS (1) CS404681A2 (es)
DD (1) DD159329A5 (es)
DE (1) DE3169348D1 (es)
DK (1) DK152490C (es)
ES (1) ES8300085A1 (es)
FI (1) FI73198C (es)
GR (1) GR75683B (es)
HU (1) HU184859B (es)
IE (1) IE52300B1 (es)
MY (1) MY8600651A (es)
NO (1) NO162283C (es)
NZ (1) NZ197238A (es)
PH (1) PH16848A (es)
PT (1) PT73112B (es)
SE (1) SE8004088L (es)
SU (1) SU1082317A3 (es)
ZA (1) ZA812983B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0053434B1 (en) * 1980-11-28 1986-08-27 American Hospital Supply Corporation Compounds and method for treatment or prophylaxis of cardiac disorders
US4593119A (en) * 1980-11-28 1986-06-03 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4559359A (en) * 1981-06-23 1985-12-17 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4455317A (en) * 1981-06-23 1984-06-19 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4454154A (en) * 1981-06-23 1984-06-12 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4578403A (en) * 1981-06-23 1986-03-25 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
CA1211111A (en) * 1982-02-15 1986-09-09 Isao Yanagisawa Process for preparing novel pyrimidone compounds
EP0117089B1 (en) * 1983-02-03 1988-12-14 The Regents Of The University Of California Beta-adrenergic antagonist compounds and derivatives of beta-adrenergic antagonists
US4687873A (en) * 1983-02-03 1987-08-18 The Regents Of The University Of California Derivatives of β-adrenergic antagonists
JPS63162660A (ja) * 1986-12-26 1988-07-06 Toray Ind Inc 感光性化合物の製造方法
US5084466A (en) * 1989-01-31 1992-01-28 Hoffmann-La Roche Inc. Novel carboxamide pyridine compounds which have useful pharmaceutical utility
US5256812A (en) * 1989-01-31 1993-10-26 Hoffmann-La Roche Inc. Carboxamides and sulfonamides
JP3807573B2 (ja) 1997-11-20 2006-08-09 住友電気工業株式会社 ディスクブレーキ用パッド

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB673413A (en) * 1950-03-22 1952-06-04 Rhone Poulenc Sa New local anaesthetics which are substituted benzoic esters and processes for making the same
CH512427A (de) * 1967-12-18 1971-09-15 Boehringer Sohn Ingelheim Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-sec. -alkylaminopropanen
DE1922003C3 (de) * 1969-04-30 1979-10-11 Boehringer Mannheim Gmbh, 6800 Mannheim N-(3-Aryloxy-2-hydroxypropyl)-aminocarbonsäuren, deren Ester, Amide und Salze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung von Herzinsuffizienz
SE354851B (es) * 1970-02-18 1973-03-26 Haessle Ab
FR2132570B1 (es) * 1971-04-09 1974-08-02 Lipha
DE2324584A1 (de) * 1972-06-08 1974-01-10 Ciba Geigy Ag Neue amine und verfahren zu ihrer herstellung
SE386892B (sv) * 1972-07-06 1976-08-23 Haessle Ab Forfarande for framstellning av oxaminoforeningar
SE388849B (sv) * 1974-02-14 1976-10-18 Haessle Ab Forfarande for framstellning av nya aminer med beta-receptorstimulerande verkan
PT66890B (fr) * 1976-08-21 1979-01-25 Hexachimie Procede pour la preparation des aryloxy-1 amino-3 propanol-2
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4450173A (en) * 1980-11-28 1984-05-22 American Hospital Supply Corporation Compounds and method for treatment or prophylaxis of cardiac disorders

Also Published As

Publication number Publication date
EP0041492B1 (en) 1985-03-20
JPH0260657B2 (es) 1990-12-17
SU1082317A3 (ru) 1984-03-23
NO162283C (no) 1989-12-06
CS404681A2 (en) 1990-10-12
NO162283B (no) 1989-08-28
DK152490C (da) 1988-08-15
IE811207L (en) 1981-12-02
PT73112A (en) 1981-07-01
DE3169348D1 (en) 1985-04-25
DD159329A5 (de) 1983-03-02
FI811672L (fi) 1981-12-03
JPS5724334A (en) 1982-02-08
ZA812983B (en) 1982-05-26
GR75683B (es) 1984-08-02
DK239481A (da) 1981-12-03
US5051446A (en) 1991-09-24
PH16848A (en) 1984-03-19
MY8600651A (en) 1986-12-31
EP0041492A1 (en) 1981-12-09
FI73198B (fi) 1987-05-29
KR830006181A (ko) 1983-09-20
IE52300B1 (en) 1987-09-02
ATE12223T1 (de) 1985-04-15
FI73198C (fi) 1987-09-10
AU7116781A (en) 1981-12-10
AU549890B2 (en) 1986-02-20
ES502654A0 (es) 1982-10-01
DK152490B (da) 1988-03-07
KR850000872B1 (ko) 1985-06-22
SE8004088L (sv) 1981-12-03
NZ197238A (en) 1984-12-14
PT73112B (en) 1983-05-11
HU184859B (en) 1984-10-29
NO811798L (no) 1981-12-03
CA1167465A (en) 1984-05-15

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Legal Events

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PC1A Transfer granted