PT3744835T - Proteínas de fusão modificadoras do adn e métodos de utilização das mesmas - Google Patents

Proteínas de fusão modificadoras do adn e métodos de utilização das mesmas

Info

Publication number
PT3744835T
PT3744835T PT201837408T PT20183740T PT3744835T PT 3744835 T PT3744835 T PT 3744835T PT 201837408 T PT201837408 T PT 201837408T PT 20183740 T PT20183740 T PT 20183740T PT 3744835 T PT3744835 T PT 3744835T
Authority
PT
Portugal
Prior art keywords
methods
fusion proteins
dna modifying
modifying fusion
dna
Prior art date
Application number
PT201837408T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Massachusetts Gen Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Gen Hospital filed Critical Massachusetts Gen Hospital
Publication of PT3744835T publication Critical patent/PT3744835T/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
    • C07K2319/81—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor containing a Zn-finger domain for DNA binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT201837408T 2012-05-29 2013-05-29 Proteínas de fusão modificadoras do adn e métodos de utilização das mesmas PT3744835T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261652711P 2012-05-29 2012-05-29
US13/838,520 US9890364B2 (en) 2012-05-29 2013-03-15 TAL-Tet1 fusion proteins and methods of use thereof

Publications (1)

Publication Number Publication Date
PT3744835T true PT3744835T (pt) 2024-05-31

Family

ID=49670524

Family Applications (1)

Application Number Title Priority Date Filing Date
PT201837408T PT3744835T (pt) 2012-05-29 2013-05-29 Proteínas de fusão modificadoras do adn e métodos de utilização das mesmas

Country Status (5)

Country Link
US (3) US9890364B2 (da)
EP (4) EP3747999B1 (da)
DK (1) DK3744835T5 (da)
PT (1) PT3744835T (da)
WO (1) WO2013181228A1 (da)

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Also Published As

Publication number Publication date
DK3744835T5 (da) 2024-08-26
DK3744835T3 (da) 2024-05-06
EP2879693A4 (en) 2016-04-13
EP2879693A1 (en) 2015-06-10
EP3747999B1 (en) 2021-09-15
US9890364B2 (en) 2018-02-13
US20180187168A1 (en) 2018-07-05
EP4368249A2 (en) 2024-05-15
EP3747999A1 (en) 2020-12-09
EP2879693B1 (en) 2020-07-08
EP4368249A3 (en) 2024-07-24
WO2013181228A1 (en) 2013-12-05
US20130323220A1 (en) 2013-12-05
EP3744835A1 (en) 2020-12-02
US10894950B2 (en) 2021-01-19
US20210155907A1 (en) 2021-05-27
EP3744835B1 (en) 2024-01-31

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