PT3709996T - Derivado de coumarina para terapia ou profilaxia de um distúrbio de proliferação celular - Google Patents
Derivado de coumarina para terapia ou profilaxia de um distúrbio de proliferação celularInfo
- Publication number
- PT3709996T PT3709996T PT187248927T PT18724892T PT3709996T PT 3709996 T PT3709996 T PT 3709996T PT 187248927 T PT187248927 T PT 187248927T PT 18724892 T PT18724892 T PT 18724892T PT 3709996 T PT3709996 T PT 3709996T
- Authority
- PT
- Portugal
- Prior art keywords
- prophylaxis
- therapy
- cell proliferative
- proliferative disorder
- coumarin derivative
- Prior art date
Links
- CFNMUZCFSDMZPQ-GHXNOFRVSA-N 7-[(z)-3-methyl-4-(4-methyl-5-oxo-2h-furan-2-yl)but-2-enoxy]chromen-2-one Chemical compound C=1C=C2C=CC(=O)OC2=CC=1OC/C=C(/C)CC1OC(=O)C(C)=C1 CFNMUZCFSDMZPQ-GHXNOFRVSA-N 0.000 title 1
- 230000002062 proliferating effect Effects 0.000 title 1
- 238000011321 prophylaxis Methods 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2017/079506 WO2019096397A1 (en) | 2017-11-16 | 2017-11-16 | Coumarin derivative for therapy or prophylaxis of a cell proliferative disorder |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3709996T true PT3709996T (pt) | 2024-04-15 |
Family
ID=60331633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT187248927T PT3709996T (pt) | 2017-11-16 | 2018-05-16 | Derivado de coumarina para terapia ou profilaxia de um distúrbio de proliferação celular |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US11400090B2 (pt) |
| EP (2) | EP3709996B1 (pt) |
| KR (1) | KR102669822B1 (pt) |
| CN (1) | CN111542317A (pt) |
| AU (1) | AU2018369325A1 (pt) |
| BR (1) | BR112020009452A2 (pt) |
| CA (1) | CA3082619A1 (pt) |
| DK (1) | DK3709996T3 (pt) |
| FI (1) | FI3709996T3 (pt) |
| MX (2) | MX2020005006A (pt) |
| PT (1) | PT3709996T (pt) |
| RU (1) | RU2760006C1 (pt) |
| SG (1) | SG11202004376TA (pt) |
| TW (1) | TWI795405B (pt) |
| WO (2) | WO2019096397A1 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021047783A1 (en) * | 2019-09-13 | 2021-03-18 | The Institute Of Cancer Research: Royal Cancer Hospital | Vs-6063 in combination with ch5126766 for the treatment of cancer |
| US11873296B2 (en) | 2022-06-07 | 2024-01-16 | Verastem, Inc. | Solid forms of a dual RAF/MEK inhibitor |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9920908D0 (en) | 1999-09-03 | 1999-11-10 | Indena Spa | Chalcone coumarins |
| AR059339A1 (es) | 2006-02-09 | 2008-03-26 | Chugai Pharmaceutical Co Ltd | Derivados de la cumarina para trastornos proliferativos de celulas, composicion farmaceutica y agente terapeutico que los contiene |
| JP5325103B2 (ja) | 2007-07-20 | 2013-10-23 | 中外製薬株式会社 | ｐ２７蛋白質誘導剤 |
| US9133174B2 (en) | 2011-09-05 | 2015-09-15 | Chugai Seiyaku Kabushiki Kaisha | Method for producing coumarin derivative |
-
2017
- 2017-11-16 RU RU2020119399A patent/RU2760006C1/ru active
- 2017-11-16 WO PCT/EP2017/079506 patent/WO2019096397A1/en active Application Filing
-
2018
- 2018-05-16 CN CN201880073974.9A patent/CN111542317A/zh active Pending
- 2018-05-16 AU AU2018369325A patent/AU2018369325A1/en active Pending
- 2018-05-16 TW TW107116587A patent/TWI795405B/zh active
- 2018-05-16 EP EP18724892.7A patent/EP3709996B1/en active Active
- 2018-05-16 CA CA3082619A patent/CA3082619A1/en active Pending
- 2018-05-16 KR KR1020207017064A patent/KR102669822B1/ko active IP Right Grant
- 2018-05-16 SG SG11202004376TA patent/SG11202004376TA/en unknown
- 2018-05-16 PT PT187248927T patent/PT3709996T/pt unknown
- 2018-05-16 DK DK18724892.7T patent/DK3709996T3/da active
- 2018-05-16 MX MX2020005006A patent/MX2020005006A/es unknown
- 2018-05-16 US US16/764,242 patent/US11400090B2/en active Active
- 2018-05-16 EP EP24159280.7A patent/EP4364807A2/en active Pending
- 2018-05-16 FI FIEP18724892.7T patent/FI3709996T3/fi active
- 2018-05-16 BR BR112020009452-8A patent/BR112020009452A2/pt unknown
- 2018-05-16 WO PCT/EP2018/062805 patent/WO2019096449A1/en unknown
-
2020
- 2020-07-13 MX MX2023011203A patent/MX2023011203A/es unknown
-
2022
- 2022-06-27 US US17/850,463 patent/US20230012116A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR102669822B1 (ko) | 2024-05-28 |
| EP3709996B1 (en) | 2024-02-28 |
| US20210330670A1 (en) | 2021-10-28 |
| DK3709996T3 (da) | 2024-03-11 |
| WO2019096397A1 (en) | 2019-05-23 |
| WO2019096449A1 (en) | 2019-05-23 |
| US11400090B2 (en) | 2022-08-02 |
| SG11202004376TA (en) | 2020-06-29 |
| CN111542317A (zh) | 2020-08-14 |
| FI3709996T3 (fi) | 2024-03-22 |
| BR112020009452A2 (pt) | 2020-12-22 |
| MX2020005006A (es) | 2020-10-12 |
| EP3709996A1 (en) | 2020-09-23 |
| US20230012116A1 (en) | 2023-01-12 |
| EP4364807A2 (en) | 2024-05-08 |
| TWI795405B (zh) | 2023-03-11 |
| AU2018369325A1 (en) | 2020-06-18 |
| RU2760006C1 (ru) | 2021-11-22 |
| TW201922254A (zh) | 2019-06-16 |
| KR20200096538A (ko) | 2020-08-12 |
| CA3082619A1 (en) | 2019-05-23 |
| MX2023011203A (es) | 2023-10-02 |
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