PT3585382T - Utilização de 3-[5-amino-4-(3-cianobenzoil)-pirazol-1-il]-n-ciclopropil-4-metilbenzamida no tratamento de exacerbações agudas da doença pulmonar obstrutiva crónica - Google Patents

Utilização de 3-[5-amino-4-(3-cianobenzoil)-pirazol-1-il]-n-ciclopropil-4-metilbenzamida no tratamento de exacerbações agudas da doença pulmonar obstrutiva crónica

Info

Publication number
PT3585382T
PT3585382T PT188193650T PT18819365T PT3585382T PT 3585382 T PT3585382 T PT 3585382T PT 188193650 T PT188193650 T PT 188193650T PT 18819365 T PT18819365 T PT 18819365T PT 3585382 T PT3585382 T PT 3585382T
Authority
PT
Portugal
Prior art keywords
cyanobenzoyl
methylbenzamide
pyrazol
cyclopropyl
amino
Prior art date
Application number
PT188193650T
Other languages
English (en)
Original Assignee
Mereo Biopharma 1 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1720622.8A external-priority patent/GB201720622D0/en
Priority claimed from GBGB1802354.9A external-priority patent/GB201802354D0/en
Application filed by Mereo Biopharma 1 Ltd filed Critical Mereo Biopharma 1 Ltd
Publication of PT3585382T publication Critical patent/PT3585382T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT188193650T 2017-12-11 2018-12-11 Utilização de 3-[5-amino-4-(3-cianobenzoil)-pirazol-1-il]-n-ciclopropil-4-metilbenzamida no tratamento de exacerbações agudas da doença pulmonar obstrutiva crónica PT3585382T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1720622.8A GB201720622D0 (en) 2017-12-11 2017-12-11 Use of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamide in the treatment of acute exacerbations of chronic obstructive pulmonary
GBGB1802354.9A GB201802354D0 (en) 2018-02-13 2018-02-13 Treatment of chronic obstructive pulmonary disease

Publications (1)

Publication Number Publication Date
PT3585382T true PT3585382T (pt) 2021-08-19

Family

ID=64665364

Family Applications (1)

Application Number Title Priority Date Filing Date
PT188193650T PT3585382T (pt) 2017-12-11 2018-12-11 Utilização de 3-[5-amino-4-(3-cianobenzoil)-pirazol-1-il]-n-ciclopropil-4-metilbenzamida no tratamento de exacerbações agudas da doença pulmonar obstrutiva crónica

Country Status (12)

Country Link
US (1) US11701341B2 (pt)
EP (1) EP3585382B1 (pt)
JP (1) JP7280627B2 (pt)
KR (1) KR20200097311A (pt)
AU (1) AU2018382895B2 (pt)
CA (1) CA3085545A1 (pt)
DK (1) DK3585382T3 (pt)
ES (1) ES2884789T3 (pt)
HU (1) HUE055425T2 (pt)
PL (1) PL3585382T3 (pt)
PT (1) PT3585382T (pt)
WO (1) WO2019116021A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7280627B2 (ja) 2017-12-11 2023-05-24 メレオ バイオファーマ １ リミテッド 慢性閉塞性肺疾患の急性増悪の処置における３－［５－アミノ－４－（３－シアノベンゾイル）－ピラゾール－１－イル］－ｎ－シクロプロピル－４－メチルベンズアミドの使用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9501841D0 (en) 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
US6598603B1 (en) 1997-12-31 2003-07-29 Astra Aktiebolag Method for treating respiratory diseases
PT1641764E (pt) 2003-06-26 2011-10-27 Novartis Ag Inibidores de p38 quinase a base de heterociclo de 5 elementos
TWI556829B (zh) 2004-04-09 2016-11-11 艾伯維生物技術有限責任公司 用於治療ＴＮＦα相關失調症之多重可變劑量療法
GB0409703D0 (en) 2004-04-30 2004-06-02 Vectura Ltd Pharmaceutical compositions
GB0603684D0 (en) 2006-02-23 2006-04-05 Novartis Ag Organic compounds
PT2827860T (pt) * 2012-03-20 2016-12-20 Mereo Biopharma 1 Ltd Utilização de um derivado de pirazole no tratamento de exacerbações agudas da doença pulmonar obstructiva crónica
JP6741773B2 (ja) * 2016-03-08 2020-08-19 メレオ バイオファーマ １ リミテッド 炎症状態の急性増悪の治療のための投与レジメン
RU2713203C1 (ru) * 2016-03-08 2020-02-04 Мерео Байофарма 1 Лимитед Режим дозирования при лечении острых обострений хронической обструктивной болезни легких
JP7280627B2 (ja) 2017-12-11 2023-05-24 メレオ バイオファーマ １ リミテッド 慢性閉塞性肺疾患の急性増悪の処置における３－［５－アミノ－４－（３－シアノベンゾイル）－ピラゾール－１－イル］－ｎ－シクロプロピル－４－メチルベンズアミドの使用
ES2882978T3 (es) 2017-12-11 2021-12-03 Mereo Biopharma 1 Ltd Uso de 3-[5-amino-4-(3-cianobenzoil)-pirazol-1-il]-N-ciclopropil-4-metilbenzamida en la prevención de exacerbaciones agudas de la enfermedad de obstrucción pulmonar crónica

Also Published As

Publication number Publication date
AU2018382895B2 (en) 2024-05-16
AU2018382895A1 (en) 2020-06-25
DK3585382T3 (da) 2021-08-09
JP2021505631A (ja) 2021-02-18
EP3585382A1 (en) 2020-01-01
US20200352909A1 (en) 2020-11-12
EP3585382B1 (en) 2021-07-14
PL3585382T3 (pl) 2021-12-06
CA3085545A1 (en) 2019-06-20
JP7280627B2 (ja) 2023-05-24
US11701341B2 (en) 2023-07-18
KR20200097311A (ko) 2020-08-18
WO2019116021A1 (en) 2019-06-20
ES2884789T3 (es) 2021-12-13
HUE055425T2 (hu) 2021-11-29

Similar Documents

Publication Publication Date Title
HK1251257A1 (zh) 用於醫治疾病的外泌體的用途
EP3554342C0 (en) TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A TNF INHIBITOR
HK1244453A1 (zh) 使用syk抑制劑對慢性移植物抗宿主病的治療
IL254142B (en) Tredifitant for use in the treatment of a disease or medical condition that responds to Tredifitent
ZA201607740B (en) Treatment of the complications of chronic liver disease with caspase inhibitors
HK1200352A1 (zh) 吡唑衍生物用於治療慢性阻塞性肺病急性惡化的用途
GB201711190D0 (en) Use of cannabininoids in the treatment of a neurodegenerative disease or disorder
LT3630164T (lt) Dulagliutidas, skirtas lėtinės inkstų ligos gydymui
IL275349A (en) Use of hM4Di in the treatment of seizure disorders
PL3585383T3 (pl) Zastosowanie 3-[5-amino-4-(3-cyjanobenzoilo)pirazol-1-ilo]- n-cyklopropylo- 4-metylobenzamidu w zapobieganiu ostrym zaostrzeniom przewlekłej obturacyjnej choroby płuc
HUE050456T2 (hu) Dimetil-amino-mikeliolid tüdõfibrózis kezelésében történõ alkalmazásra
HUE055425T2 (hu) 3-[5-amino-4-(3-cianobenzoil)-pirazol-1-il]-N-ciklopropil-4-metilbenzamid alkalmazása krónikus elzáródásos tüdõbetegség akut fokozódásának kezelésében
GB201515244D0 (en) Treatment of inflammatory disease or condition
DK3050574T3 (da) Anvendelse af plerixafor til behandling og/eller forebyggelse af akutte forværringer af kronisk obstruktiv lungesygdom
IL256413B (en) IL-8 inhibitors for use in the treatment of certain urological disorders
GB201720622D0 (en) Use of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamide in the treatment of acute exacerbations of chronic obstructive pulmonary
GB201720624D0 (en) Use of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamide in the prevention or reduction of acute exacerbations
EP3383415A4 (en) USE OF MITOCHONDRIAL IRON RADIATORS FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE LUNG DISEASE
GB201802353D0 (en) Treatment of chronic obstructive pulmonary disease
GB201802354D0 (en) Treatment of chronic obstructive pulmonary disease
TH1401005467B (th) การใช้อนุพันธ์ไพราโซลในการรักษาการกำเริบแบบเฉียบพลันของโรคปอดอุดกั้นชนิดเรื้อรัง