DK3585382T3 - Anvendelse af 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamid i behandlingen af akutte forværringer af kronisk obstruktiv lungesygdom - Google Patents

Anvendelse af 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamid i behandlingen af akutte forværringer af kronisk obstruktiv lungesygdom Download PDF

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Publication number
DK3585382T3
DK3585382T3 DK18819365.0T DK18819365T DK3585382T3 DK 3585382 T3 DK3585382 T3 DK 3585382T3 DK 18819365 T DK18819365 T DK 18819365T DK 3585382 T3 DK3585382 T3 DK 3585382T3
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DK
Denmark
Prior art keywords
cyanobenzoyl
methylbenzamide
pyrazol
cyclopropyl
extensions
Prior art date
Application number
DK18819365.0T
Other languages
English (en)
Inventor
Alastair Mackinnon
Jacqueline Parkin
Original Assignee
Mereo Biopharma 1 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1720622.8A external-priority patent/GB201720622D0/en
Priority claimed from GBGB1802354.9A external-priority patent/GB201802354D0/en
Application filed by Mereo Biopharma 1 Ltd filed Critical Mereo Biopharma 1 Ltd
Application granted granted Critical
Publication of DK3585382T3 publication Critical patent/DK3585382T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK18819365.0T 2017-12-11 2018-12-11 Anvendelse af 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamid i behandlingen af akutte forværringer af kronisk obstruktiv lungesygdom DK3585382T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1720622.8A GB201720622D0 (en) 2017-12-11 2017-12-11 Use of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamide in the treatment of acute exacerbations of chronic obstructive pulmonary
GBGB1802354.9A GB201802354D0 (en) 2018-02-13 2018-02-13 Treatment of chronic obstructive pulmonary disease
PCT/GB2018/053590 WO2019116021A1 (en) 2017-12-11 2018-12-11 Use of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamide in the treatment of acute exacerbations of chronic obstructive pulmonary disease

Publications (1)

Publication Number Publication Date
DK3585382T3 true DK3585382T3 (da) 2021-08-09

Family

ID=64665364

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18819365.0T DK3585382T3 (da) 2017-12-11 2018-12-11 Anvendelse af 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamid i behandlingen af akutte forværringer af kronisk obstruktiv lungesygdom

Country Status (12)

Country Link
US (1) US11701341B2 (da)
EP (1) EP3585382B1 (da)
JP (1) JP7280627B2 (da)
KR (1) KR20200097311A (da)
AU (1) AU2018382895A1 (da)
CA (1) CA3085545A1 (da)
DK (1) DK3585382T3 (da)
ES (1) ES2884789T3 (da)
HU (1) HUE055425T2 (da)
PL (1) PL3585382T3 (da)
PT (1) PT3585382T (da)
WO (1) WO2019116021A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3585382B1 (en) 2017-12-11 2021-07-14 Mereo BioPharma 1 Limited Use of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamide in the treatment of acute exacerbations of chronic obstructive pulmonary disease

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9501841D0 (en) 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
US6598603B1 (en) 1997-12-31 2003-07-29 Astra Aktiebolag Method for treating respiratory diseases
TWI452035B (zh) * 2003-06-26 2014-09-11 Novartis Ag 以５員雜環為主之ｐ３８激酶抑制劑
TW201705980A (zh) 2004-04-09 2017-02-16 艾伯維生物技術有限責任公司 用於治療ＴＮＦα相關失調症之多重可變劑量療法
GB0409703D0 (en) 2004-04-30 2004-06-02 Vectura Ltd Pharmaceutical compositions
GB0603684D0 (en) 2006-02-23 2006-04-05 Novartis Ag Organic compounds
NZ628392A (en) * 2012-03-20 2016-06-24 Mereo Biopharma 1 Ltd Use of a pyrazole derivative in the treatment of acute exacerbations of chronic obstructive pulmonary disease
CA3016488C (en) * 2016-03-08 2023-04-11 Mereo Biopharma 1 Limited Dosage regimen for the treatment of acute exacerbations of chronic obstructive pulmonary disease
WO2017153701A1 (en) * 2016-03-08 2017-09-14 Mereo Biopharma 1 Limited Dosage regimen for the treatment of acute exacerbations of inflammatory conditions
HUE054266T2 (hu) 2017-12-11 2021-08-30 Mereo Biopharma 1 Ltd 3-[5-amino-4-(3-cianobenzoil)-pirazol-1-il]-N-ciklopropil-4-metilbenzamid alkalmazása krónikus obstruktív tüdõbetegség akut megjelenésének megelõzésében
EP3585382B1 (en) 2017-12-11 2021-07-14 Mereo BioPharma 1 Limited Use of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamide in the treatment of acute exacerbations of chronic obstructive pulmonary disease

Also Published As

Publication number Publication date
JP2021505631A (ja) 2021-02-18
US20200352909A1 (en) 2020-11-12
AU2018382895A1 (en) 2020-06-25
ES2884789T3 (es) 2021-12-13
EP3585382A1 (en) 2020-01-01
KR20200097311A (ko) 2020-08-18
HUE055425T2 (hu) 2021-11-29
WO2019116021A1 (en) 2019-06-20
CA3085545A1 (en) 2019-06-20
JP7280627B2 (ja) 2023-05-24
US11701341B2 (en) 2023-07-18
EP3585382B1 (en) 2021-07-14
PL3585382T3 (pl) 2021-12-06
PT3585382T (pt) 2021-08-19

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