PT3580199T - Método para a preparação num vaso de compostos organoiodados - Google Patents

Método para a preparação num vaso de compostos organoiodados

Info

Publication number
PT3580199T
PT3580199T PT187036025T PT18703602T PT3580199T PT 3580199 T PT3580199 T PT 3580199T PT 187036025 T PT187036025 T PT 187036025T PT 18703602 T PT18703602 T PT 18703602T PT 3580199 T PT3580199 T PT 3580199T
Authority
PT
Portugal
Prior art keywords
organo
iodinated compounds
pot production
pot
production
Prior art date
Application number
PT187036025T
Other languages
English (en)
Original Assignee
Guerbet Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guerbet Sa filed Critical Guerbet Sa
Publication of PT3580199T publication Critical patent/PT3580199T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D309/06Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/16Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT187036025T 2017-02-10 2018-02-09 Método para a preparação num vaso de compostos organoiodados PT3580199T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1751121A FR3062850B1 (fr) 2017-02-10 2017-02-10 Procede de preparation monotope de composes organo-iodes

Publications (1)

Publication Number Publication Date
PT3580199T true PT3580199T (pt) 2023-06-26

Family

ID=59381338

Family Applications (1)

Application Number Title Priority Date Filing Date
PT187036025T PT3580199T (pt) 2017-02-10 2018-02-09 Método para a preparação num vaso de compostos organoiodados

Country Status (10)

Country Link
US (1) US10836711B2 (pt)
EP (1) EP3580199B1 (pt)
CN (1) CN110267937B (pt)
AR (1) AR111036A1 (pt)
ES (1) ES2948507T3 (pt)
FR (2) FR3062850B1 (pt)
IL (1) IL268465B (pt)
PT (1) PT3580199T (pt)
TW (1) TWI770120B (pt)
WO (1) WO2018146285A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3084668A1 (fr) * 2018-08-02 2020-02-07 Guerbet Procede de preparation monotope de composes organo-iodes intermediaires a la synthese du ioversol
CN110903275A (zh) * 2018-09-14 2020-03-24 苏州科伦药物研究有限公司 制备碘比醇的方法、其中间体及其制备方法
CN116354842A (zh) * 2021-12-20 2023-06-30 重庆圣华曦药业股份有限公司 一种改进的碘美普尔制备方法及其在制剂中的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3210412A (en) * 1962-02-06 1965-10-05 Mallinckrodt Chemical Works m-(alkanamidoalkanamido)-2, 4, 6-triiodobenzoic acid compounds
US4141894A (en) * 1976-11-02 1979-02-27 Eli Lilly And Company Trans-5a-aryl-decahydrobenzazepines
US5075502A (en) * 1989-12-13 1991-12-24 Mallinckrodt, Inc. Nonionic x-ray contrast agents, compositions and methods
AU2823795A (en) * 1994-06-24 1996-01-19 Nanosystems L.L.C. 2,4,6-triiodo-5-substituted-amino-isophthalate esters useful as x-ray contrast agents for medical diagnostic imaging
IT1271107B (it) 1994-11-29 1997-05-26 Zambon Spa Processo per la preparazione di un intermedio utile nella sintesi di composti organici
EP0773925B1 (en) 1995-05-23 2000-02-09 Fructamine S.P.A. Process for the preparation of a dicarboxylic acid dichloride
JP4801661B2 (ja) * 2005-03-18 2011-10-26 マナック株式会社 5−アミノ−2,4,6−トリヨードイソフタル酸誘導体のアセチル化方法
EP2230227A1 (en) * 2009-03-20 2010-09-22 Bracco Imaging S.p.A Process for the preparation of triiodinated carboxylic aromatic derivatives
PT105770B (pt) * 2011-06-24 2013-07-08 Hovione Farmaciencia S A Novo intermediário e seu uso na preparação de agente de contrate triiodado
CN102887833B (zh) * 2011-07-21 2014-10-22 浙江司太立制药股份有限公司 一种含碘双聚体造影剂
GB2496971A (en) * 2011-11-25 2013-05-29 Ge Healthcare As Preparation of X-ray contrast agents

Also Published As

Publication number Publication date
WO2018146285A1 (fr) 2018-08-16
EP3580199A1 (fr) 2019-12-18
US10836711B2 (en) 2020-11-17
FR3062851B1 (fr) 2020-05-22
AR111036A1 (es) 2019-05-29
TW201831441A (zh) 2018-09-01
IL268465A (en) 2019-09-26
US20200002269A1 (en) 2020-01-02
CN110267937A (zh) 2019-09-20
FR3062850A1 (fr) 2018-08-17
TWI770120B (zh) 2022-07-11
FR3062851A1 (fr) 2018-08-17
CN110267937B (zh) 2022-09-23
FR3062850B1 (fr) 2020-01-31
IL268465B (en) 2022-01-01
ES2948507T3 (es) 2023-09-13
EP3580199B1 (fr) 2023-04-05

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