PT3544977T - Um sal maleato da base livre de n-[5-(aminossulfonil)-4-metil-1,3-tiazol-2-il]-n-metil-2-[4-(2-piridinil)-fenil]-acetamida, formulações farmacêuticas, métodos de produção e suas utilizações para o tratamento de vírus herpes - Google Patents

Um sal maleato da base livre de n-[5-(aminossulfonil)-4-metil-1,3-tiazol-2-il]-n-metil-2-[4-(2-piridinil)-fenil]-acetamida, formulações farmacêuticas, métodos de produção e suas utilizações para o tratamento de vírus herpes

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Publication number
PT3544977T
PT3544977T PT178165445T PT17816544T PT3544977T PT 3544977 T PT3544977 T PT 3544977T PT 178165445 T PT178165445 T PT 178165445T PT 17816544 T PT17816544 T PT 17816544T PT 3544977 T PT3544977 T PT 3544977T
Authority
PT
Portugal
Prior art keywords
methyl
aminosulfonyl
thiazol
pyridinyl
acetamide
Prior art date
Application number
PT178165445T
Other languages
English (en)
Original Assignee
Aicuris Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aicuris Gmbh & Co Kg filed Critical Aicuris Gmbh & Co Kg
Publication of PT3544977T publication Critical patent/PT3544977T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT178165445T 2016-11-28 2017-11-28 Um sal maleato da base livre de n-[5-(aminossulfonil)-4-metil-1,3-tiazol-2-il]-n-metil-2-[4-(2-piridinil)-fenil]-acetamida, formulações farmacêuticas, métodos de produção e suas utilizações para o tratamento de vírus herpes PT3544977T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16201009 2016-11-28

Publications (1)

Publication Number Publication Date
PT3544977T true PT3544977T (pt) 2021-06-23

Family

ID=57421722

Family Applications (1)

Application Number Title Priority Date Filing Date
PT178165445T PT3544977T (pt) 2016-11-28 2017-11-28 Um sal maleato da base livre de n-[5-(aminossulfonil)-4-metil-1,3-tiazol-2-il]-n-metil-2-[4-(2-piridinil)-fenil]-acetamida, formulações farmacêuticas, métodos de produção e suas utilizações para o tratamento de vírus herpes

Country Status (14)

Country Link
US (2) US11266636B2 (pt)
EP (2) EP3892620A1 (pt)
JP (2) JP7316214B2 (pt)
CN (3) CN117186084A (pt)
AR (1) AR110251A1 (pt)
AU (4) AU2017365639B2 (pt)
CA (1) CA3045063A1 (pt)
ES (1) ES2877854T3 (pt)
HU (1) HUE054845T2 (pt)
PL (1) PL3544977T3 (pt)
PT (1) PT3544977T (pt)
TW (3) TWI808591B (pt)
UY (1) UY37498A (pt)
WO (1) WO2018096177A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2573085A1 (en) 2011-09-26 2013-03-27 AiCuris GmbH & Co. KG N-[5-(aminosulfonyl)-4methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl] acetamide mesylate monohydrate having a specific particle size distribution range and a specific surface area range
HUE054845T2 (hu) * 2016-11-28 2021-10-28 Aicuris Gmbh & Co Kg Az N-[5-(amino-szulfonil)-4-metil-1,3-tiazol-2-il]-N-metil-2-[4-(2-piridinil)fenil]acetamid szabad bázis maleát sója, gyógyászati készítmények, elõállítási eljárások és Herpes vírusok kezelésére történõ alkalmazások
UY37496A (es) * 2016-11-28 2018-06-29 Aicuris Anti Infective Cures Gmbh Hemihidrato de la base libre de n-[5-(aminosulfonil)-4-metil-1,3-tiazol-2-il]-n-metil-2-[4-(2-piridinil)-fenil]-acetamida, métodos de fabricación y usos del mismo
HUE061307T2 (hu) 2017-10-05 2023-06-28 Innovative Molecules Gmbh Szubsztituált tiazolok enantiomerei mint vírusellenes vegyületek
TW202038947A (zh) 2018-11-28 2020-11-01 德商創新分子有限責任公司 在與溶瘤病毒之組合療法中治療癌症的解旋酶引子酶抑制劑

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6944877B1 (en) * 1999-08-27 2005-09-13 Koninklijke Philips Electronics N.V. Closed loop addressable advertising system and method of operation
DOP2000000109A (es) 1999-12-23 2002-08-30 Gerald Kleymann Derivados de tiazolilamida
DE10129714A1 (de) 2001-06-22 2003-01-02 Bayer Ag Topische Anwendung von Thiazolylamiden
DE102005014248A1 (de) 2005-03-30 2006-10-05 Aicuris Gmbh & Co. Kg Pharmazeutische Zubereitung von N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamid
ES2610398T3 (es) * 2006-07-03 2017-04-27 Sk Chemicals, Co., Ltd. Sales de derivados de pirrolopirimidinona y procedimiento para su preparación
TW201139432A (en) * 2010-03-18 2011-11-16 Kowa Co Monomaleate of benzothiazine compound
EP2598502B1 (en) * 2011-09-26 2014-05-14 AiCuris GmbH & Co. KG N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-n-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate having a specific particle size distribution range and a specific surface area range for use in pharmaceutical formulations.
EP2573086A1 (en) 2011-09-26 2013-03-27 AiCuris GmbH & Co. KG N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate
EP2573085A1 (en) 2011-09-26 2013-03-27 AiCuris GmbH & Co. KG N-[5-(aminosulfonyl)-4methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl] acetamide mesylate monohydrate having a specific particle size distribution range and a specific surface area range
EA201500836A1 (ru) * 2013-02-12 2016-02-29 Аикурис Гмбх Унд Ко. Кг Ингибиторы хеликазы-примазы для применения в способе лечения болезни альцгеймера
HUE054845T2 (hu) * 2016-11-28 2021-10-28 Aicuris Gmbh & Co Kg Az N-[5-(amino-szulfonil)-4-metil-1,3-tiazol-2-il]-N-metil-2-[4-(2-piridinil)fenil]acetamid szabad bázis maleát sója, gyógyászati készítmények, elõállítási eljárások és Herpes vírusok kezelésére történõ alkalmazások
UY37496A (es) * 2016-11-28 2018-06-29 Aicuris Anti Infective Cures Gmbh Hemihidrato de la base libre de n-[5-(aminosulfonil)-4-metil-1,3-tiazol-2-il]-n-metil-2-[4-(2-piridinil)-fenil]-acetamida, métodos de fabricación y usos del mismo

Also Published As

Publication number Publication date
TW202413354A (zh) 2024-04-01
EP3544977A1 (en) 2019-10-02
TWI753972B (zh) 2022-02-01
HUE054845T2 (hu) 2021-10-28
EP3892620A1 (en) 2021-10-13
AU2022200409A1 (en) 2022-02-17
TW202231638A (zh) 2022-08-16
UY37498A (es) 2018-06-29
AU2022200409B2 (en) 2023-03-02
CN110062755B (zh) 2023-08-29
JP7316214B2 (ja) 2023-07-27
JP2019535780A (ja) 2019-12-12
CA3045063A1 (en) 2018-05-31
AR110251A1 (es) 2019-03-13
WO2018096177A1 (en) 2018-05-31
JP2022145700A (ja) 2022-10-04
PL3544977T3 (pl) 2021-11-08
TW201825482A (zh) 2018-07-16
AU2023200773B2 (en) 2024-02-15
US12070451B2 (en) 2024-08-27
AU2021202942A1 (en) 2021-06-03
CN117186085A (zh) 2023-12-08
AU2017365639B2 (en) 2021-03-04
US20220152009A1 (en) 2022-05-19
AU2021202942B2 (en) 2022-02-17
TWI808591B (zh) 2023-07-11
AU2017365639A1 (en) 2019-06-06
US11266636B2 (en) 2022-03-08
EP3544977B1 (en) 2021-05-19
AU2023200773A1 (en) 2023-03-09
US20200289485A1 (en) 2020-09-17
CN117186084A (zh) 2023-12-08
ES2877854T3 (es) 2021-11-17
CN110062755A (zh) 2019-07-26

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