PT3454875T - Processo para a produção de celastrol e de derivados triterpénicos pentacíclicos - Google Patents

Processo para a produção de celastrol e de derivados triterpénicos pentacíclicos

Info

Publication number
PT3454875T
PT3454875T PT177220712T PT17722071T PT3454875T PT 3454875 T PT3454875 T PT 3454875T PT 177220712 T PT177220712 T PT 177220712T PT 17722071 T PT17722071 T PT 17722071T PT 3454875 T PT3454875 T PT 3454875T
Authority
PT
Portugal
Prior art keywords
celastrol
producing
pentacyclic triterpene
triterpene derivatives
derivatives
Prior art date
Application number
PT177220712T
Other languages
English (en)
Original Assignee
Fabre Pierre Dermo Cosmetique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fabre Pierre Dermo Cosmetique filed Critical Fabre Pierre Dermo Cosmetique
Publication of PT3454875T publication Critical patent/PT3454875T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H4/00Plant reproduction by tissue culture techniques ; Tissue culture techniques therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/37Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04Plant cells or tissues
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/11Preparation or pretreatment of starting material involving culturing conditions, e.g. cultivation in the dark or under defined water stress

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Environmental Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT177220712T 2016-05-12 2017-05-12 Processo para a produção de celastrol e de derivados triterpénicos pentacíclicos PT3454875T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1654240A FR3051116B1 (fr) 2016-05-12 2016-05-12 Procede de production du celastrol et de derives triterpeniques pentacycliques

Publications (1)

Publication Number Publication Date
PT3454875T true PT3454875T (pt) 2020-12-11

Family

ID=56404155

Family Applications (1)

Application Number Title Priority Date Filing Date
PT177220712T PT3454875T (pt) 2016-05-12 2017-05-12 Processo para a produção de celastrol e de derivados triterpénicos pentacíclicos

Country Status (12)

Country Link
US (1) US20190134128A1 (pt)
EP (1) EP3454875B1 (pt)
KR (1) KR102513830B1 (pt)
BR (1) BR112018073117B1 (pt)
CA (1) CA3023192A1 (pt)
ES (1) ES2831835T3 (pt)
FR (1) FR3051116B1 (pt)
MX (1) MX2018013728A (pt)
PT (1) PT3454875T (pt)
RU (1) RU2743715C1 (pt)
SG (1) SG11201809948XA (pt)
WO (1) WO2017194757A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3047665B1 (fr) * 2016-02-17 2020-12-11 Pf Medicament Celastrol et ses derives dans le traitement des tumeurs et pathologies pre-cancereuses cutanees
LU101117B1 (en) * 2019-02-07 2020-08-07 Luxembourg Institute Of Science And Tech (List) METHOD FOR PRODUCING A COMPOSITION COMPRISING A 3-O-p-COUMAROYL ESTER OF TORMENTIC ACID FROM A PLANT CELL CULTURE, APPLICATIONS THEREOF AS ANTIPARASITIC AGENT FOR THE TREATMENT OF TRYPANOSOMIASIS
FR3095754B1 (fr) * 2019-05-10 2021-11-19 Fabre Pierre Dermo Cosmetique Triterpènes pentacycliques dans le traitement du vitiligo
FR3120790B1 (fr) 2021-03-10 2024-03-15 Fabre Pierre Dermo Cosmetique Association d’un extrait de myrte et d’un extrait de Tripterygium wilfordii pour lutter contre l’inflammation induite par C. acnes
WO2023066885A1 (en) 2021-10-19 2023-04-27 Glaxosmithkline Biologicals Sa Saponin production
FR3132632A1 (fr) * 2022-02-17 2023-08-18 Pierre Fabre Dermo-Cosmetique Composition comprenant un extrait de myrte et un extrait de Tripterygium wilfordii pour lutter contre l’acné des zones non lésionnelles de la peau acnéique
WO2023242187A1 (en) 2022-06-15 2023-12-21 Glaxosmithkline Biologicals Sa Enzymatic modification of saponins

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101086642B1 (ko) * 2009-02-27 2011-11-24 강원대학교산학협력단 셀라스트롤을 유효성분으로 포함하는 알러지 질환 예방 및 치료용 조성물
FR2952072B1 (fr) * 2009-11-05 2013-09-27 Pf Medicament Procede de production de triptolide
EP2680870A4 (en) * 2011-03-01 2015-09-02 Phytomedics Corp Inc METHODS FOR TREATING PLANT EXTRACTS T. WILFORDII HOOK F.
CN103159822B (zh) * 2013-03-04 2016-05-18 华侨大学 雷公藤甲素及其衍生物组合物的制备方法

Also Published As

Publication number Publication date
RU2743715C1 (ru) 2021-02-24
BR112018073117A2 (pt) 2019-03-06
KR20190006523A (ko) 2019-01-18
KR102513830B1 (ko) 2023-03-23
EP3454875B1 (fr) 2020-09-23
BR112018073117B1 (pt) 2022-10-25
FR3051116B1 (fr) 2019-06-07
WO2017194757A1 (fr) 2017-11-16
CA3023192A1 (fr) 2017-11-16
ES2831835T3 (es) 2021-06-09
SG11201809948XA (en) 2018-12-28
EP3454875A1 (fr) 2019-03-20
MX2018013728A (es) 2019-08-01
FR3051116A1 (fr) 2017-11-17
US20190134128A1 (en) 2019-05-09

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