PT3365338T - Derivados de morfolina substituídos tendo atividade contra a dor - Google Patents
Derivados de morfolina substituídos tendo atividade contra a dorInfo
- Publication number
- PT3365338T PT3365338T PT167853480T PT16785348T PT3365338T PT 3365338 T PT3365338 T PT 3365338T PT 167853480 T PT167853480 T PT 167853480T PT 16785348 T PT16785348 T PT 16785348T PT 3365338 T PT3365338 T PT 3365338T
- Authority
- PT
- Portugal
- Prior art keywords
- activity against
- morpholine derivatives
- substituted morpholine
- against pain
- pain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15382524 | 2015-10-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3365338T true PT3365338T (pt) | 2022-10-26 |
Family
ID=54364222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT167853480T PT3365338T (pt) | 2015-10-23 | 2016-10-21 | Derivados de morfolina substituídos tendo atividade contra a dor |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10421750B2 (pt) |
| EP (1) | EP3365338B1 (pt) |
| JP (1) | JP6844822B2 (pt) |
| CN (1) | CN108137569B (pt) |
| AR (1) | AR106445A1 (pt) |
| CA (1) | CA2999940A1 (pt) |
| ES (1) | ES2929358T3 (pt) |
| MX (1) | MX2018004774A (pt) |
| PT (1) | PT3365338T (pt) |
| TW (1) | TW201734009A (pt) |
| WO (1) | WO2017067665A1 (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20200061076A1 (en) * | 2017-05-11 | 2020-02-27 | Ramot At Tel-Aviv University Ltd. | Methods of treating leukodystrophies |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6114541A (en) | 1997-03-10 | 2000-09-05 | Hoffmann-La Roche Inc. | Method for the preparation of α-Bromo-Lactam derivatives |
| US6611010B2 (en) | 1999-12-03 | 2003-08-26 | Kabushiki Kaisha Toshiba | Semiconductor device |
| FR2805818B1 (fr) * | 2000-03-03 | 2002-04-26 | Aventis Pharma Sa | Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant |
| US6479479B2 (en) | 2000-03-03 | 2002-11-12 | Aventis Pharma S.A. | Azetidine derivatives, their preparation and pharmaceutical compositions containing them |
| EP1634873A1 (en) | 2004-08-27 | 2006-03-15 | Laboratorios Del Dr. Esteve, S.A. | Sigma receptor inhibitors |
| JP2008528604A (ja) | 2005-01-25 | 2008-07-31 | グラクソ グループ リミテッド | 抗菌剤 |
| PE20061378A1 (es) | 2005-04-20 | 2006-12-03 | Smithkline Beecham Corp | INHIBIDORES DE LA ACTIVIDAD DE Akt |
| EP1829869A1 (en) | 2006-03-02 | 2007-09-05 | Laboratorios Del Dr. Esteve, S.A. | 4,5,6,7-Tetrahydrobenzo[b]thiophene derivatives and their use as sigma receptor ligands |
| EP1847542A1 (en) | 2006-04-21 | 2007-10-24 | Laboratorios del Dr. Esteve S.A. | Spiro[benzopyran] or spiro[benzofuran] derivatives which inhibit the sigma receptor |
| GB0700786D0 (en) * | 2007-01-15 | 2007-02-21 | Pfizer Ltd | Morpholine dopamine agonists for the treatment of pain |
| EP2070933A1 (en) | 2007-12-07 | 2009-06-17 | Laboratorios del Dr. Esteve S.A. | Tricyclic triazolic compounds |
| AU2012229187B2 (en) * | 2011-03-14 | 2016-11-10 | Vertex Pharmaceuticals Incorporated | Morpholine-spirocyclic piperidine amides as modulators of ion channels |
| ES2660265T3 (es) | 2011-10-07 | 2018-03-21 | Nerviano Medical Sciences S.R.L. | Derivados de 3,4-dihidropirrolo[1,2-a]pirazin-1(2h)-ona 4-alquil-sustituidos como inhibidores de cinasa |
| CA2931219A1 (en) * | 2013-12-20 | 2015-06-25 | Laboratorios Del Dr. Esteve, S.A. | Piperidine compounds having multimodal activity against pain |
-
2016
- 2016-10-21 CN CN201680061685.8A patent/CN108137569B/zh active Active
- 2016-10-21 JP JP2018519876A patent/JP6844822B2/ja active Active
- 2016-10-21 AR ARP160103226A patent/AR106445A1/es unknown
- 2016-10-21 PT PT167853480T patent/PT3365338T/pt unknown
- 2016-10-21 EP EP16785348.0A patent/EP3365338B1/en active Active
- 2016-10-21 TW TW105134202A patent/TW201734009A/zh unknown
- 2016-10-21 US US15/769,520 patent/US10421750B2/en active Active
- 2016-10-21 MX MX2018004774A patent/MX2018004774A/es unknown
- 2016-10-21 CA CA2999940A patent/CA2999940A1/en not_active Abandoned
- 2016-10-21 WO PCT/EP2016/001743 patent/WO2017067665A1/en active Application Filing
- 2016-10-21 ES ES16785348T patent/ES2929358T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| TW201734009A (zh) | 2017-10-01 |
| MX2018004774A (es) | 2018-05-30 |
| US20180305343A1 (en) | 2018-10-25 |
| CN108137569A (zh) | 2018-06-08 |
| WO2017067665A1 (en) | 2017-04-27 |
| ES2929358T3 (es) | 2022-11-28 |
| JP6844822B2 (ja) | 2021-03-17 |
| US10421750B2 (en) | 2019-09-24 |
| CA2999940A1 (en) | 2017-04-27 |
| AR106445A1 (es) | 2018-01-17 |
| EP3365338A1 (en) | 2018-08-29 |
| JP2018531949A (ja) | 2018-11-01 |
| CN108137569B (zh) | 2022-03-15 |
| EP3365338B1 (en) | 2022-08-03 |
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