HK1252275A1 - 羥烷基噻二唑衍生物 - Google Patents

羥烷基噻二唑衍生物

Info

Publication number
HK1252275A1
HK1252275A1 HK18111652.6A HK18111652A HK1252275A1 HK 1252275 A1 HK1252275 A1 HK 1252275A1 HK 18111652 A HK18111652 A HK 18111652A HK 1252275 A1 HK1252275 A1 HK 1252275A1
Authority
HK
Hong Kong
Prior art keywords
thiadiazole derivatives
hydroxyalkyl
hydroxyalkyl thiadiazole
derivatives
thiadiazole
Prior art date
Application number
HK18111652.6A
Other languages
English (en)
Inventor
Manoj Kumar Khera
Tarun Mathur
Jitendra A Sattigeri
Nobuhisa Masuda
Tsuyoshi Soneda
Yoshiko Kagoshima
Toshiyuki Konosu
Tetsuya Suzuki
Makoto Yamaoka
Ryo Itooka
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of HK1252275A1 publication Critical patent/HK1252275A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK18111652.6A 2015-09-30 2018-09-11 羥烷基噻二唑衍生物 HK1252275A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN3119DE2015 2015-09-30

Publications (1)

Publication Number Publication Date
HK1252275A1 true HK1252275A1 (zh) 2019-05-24

Family

ID=57218949

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18111652.6A HK1252275A1 (zh) 2015-09-30 2018-09-11 羥烷基噻二唑衍生物

Country Status (19)

Country Link
US (1) US10399968B2 (zh)
EP (1) EP3356361B1 (zh)
JP (1) JP6824256B2 (zh)
KR (1) KR20180054650A (zh)
CN (1) CN108137574B (zh)
AU (1) AU2016330271B2 (zh)
BR (1) BR112018006276A2 (zh)
CA (1) CA2999982C (zh)
CO (1) CO2018003548A2 (zh)
ES (1) ES2817749T3 (zh)
HK (1) HK1252275A1 (zh)
IL (1) IL258411B (zh)
MX (1) MX2018003562A (zh)
MY (1) MY184406A (zh)
PH (1) PH12018500697A1 (zh)
RU (1) RU2737892C1 (zh)
TW (1) TW201731844A (zh)
WO (1) WO2017056012A1 (zh)
ZA (1) ZA201801718B (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108137574B (zh) * 2015-09-30 2021-12-28 第一三共株式会社 羟烷基噻二唑衍生物
JP2020511457A (ja) * 2017-03-14 2020-04-16 第一三共株式会社 ヒドロキシアルキルチアジアゾール誘導体のｎ−ホスホノキシメチルプロドラッグ
US20210323957A1 (en) 2018-09-03 2021-10-21 Univerza V Ljubljani New class of dna gyrase and/or topoisomerase iv inhibitors with activity against gram-positive and gram-negative bacteria
WO2022129327A1 (en) 2020-12-17 2022-06-23 Univerza V Ljubljani New n-phenylpyrrolamide inhibitors of dna gyrase and topoisomerase iv with antibacterial activity
CN115466246B (zh) * 2021-06-11 2024-02-06 中国医学科学院药物研究所 吡咯酰哌啶胺类化合物及其用途

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200526626A (en) 2003-09-13 2005-08-16 Astrazeneca Ab Chemical compounds
UA94901C2 (ru) 2005-02-18 2011-06-25 Астразенека Аб Антибактериальные производные пиперидина
CN101163697A (zh) 2005-02-18 2008-04-16 阿斯利康(瑞典)有限公司 作为dna促旋酶和拓扑异构酶抑制剂的吡咯衍生物
WO2006087548A2 (en) 2005-02-18 2006-08-24 Astrazeneca Ab Pyrrole derivatives as dna gyrase and topoisomerase inhibitors
US20090253671A1 (en) 2005-03-04 2009-10-08 Astrazeneca Ab Tricyclic derivatives of azetidine and pyrrole with antibacterial activity
CN101171247A (zh) 2005-03-04 2008-04-30 阿斯利康(瑞典)有限公司 作为dna促旋酶和拓扑异构酶抑制剂的吡咯衍生物
JP2009520785A (ja) 2005-12-23 2009-05-28 アストラゼネカ アクチボラグ 抗菌性のピロロピリジン、ピロロピリミジン、及びピロロアゼピン
WO2008020229A2 (en) 2006-08-17 2008-02-21 Astrazeneca Ab Antibacterial pyrrolecarboxamides
TW200819437A (en) * 2006-08-17 2008-05-01 Astrazeneca Ab Chemical compounds
WO2008020227A2 (en) 2006-08-17 2008-02-21 Astrazeneca Ab Antibacterial pyrrolecarboxamides
TW200906412A (en) 2007-06-12 2009-02-16 Astrazeneca Ab Piperidine compounds and uses thereof
TWI498115B (zh) 2007-12-27 2015-09-01 Daiichi Sankyo Co Ltd 咪唑羰基化合物
US20120108565A1 (en) 2008-07-30 2012-05-03 Lalima Sharma Pyrrole carboxylic acid derivatives as antibacterial agents
TW201026694A (en) * 2008-12-12 2010-07-16 Astrazeneca Ab Compound 468
TW201026695A (en) 2008-12-12 2010-07-16 Astrazeneca Ab Piperidine compounds and uses thereof-596
JP2011026305A (ja) * 2009-06-24 2011-02-10 Daiichi Sankyo Co Ltd イミダゾールカルボニル化合物を含有する医薬組成物
EP2906216B1 (en) 2012-10-10 2020-06-24 Kumar, Ajay Inhibitors of dna gyrase for the treatment of bacterial infections
CN108137574B (zh) * 2015-09-30 2021-12-28 第一三共株式会社 羟烷基噻二唑衍生物

Also Published As

Publication number Publication date
AU2016330271A1 (en) 2018-04-12
US10399968B2 (en) 2019-09-03
CO2018003548A2 (es) 2018-07-19
CN108137574A (zh) 2018-06-08
US20180327399A1 (en) 2018-11-15
BR112018006276A2 (pt) 2018-10-16
JP6824256B2 (ja) 2021-02-03
ZA201801718B (en) 2019-01-30
IL258411A (en) 2018-05-31
KR20180054650A (ko) 2018-05-24
MY184406A (en) 2021-04-01
CA2999982C (en) 2020-07-28
CN108137574B (zh) 2021-12-28
EP3356361A1 (en) 2018-08-08
ES2817749T3 (es) 2021-04-08
PH12018500697A1 (en) 2018-10-01
AU2016330271B2 (en) 2020-04-30
EP3356361B1 (en) 2020-07-08
TW201731844A (zh) 2017-09-16
JP2018529696A (ja) 2018-10-11
CA2999982A1 (en) 2017-04-06
WO2017056012A1 (en) 2017-04-06
MX2018003562A (es) 2018-06-19
RU2737892C1 (ru) 2020-12-04
IL258411B (en) 2021-08-31

Similar Documents

Publication Publication Date Title
HK1255045A1 (zh) 取代的氧代吡啶衍生物
SG11201706729SA (en) Derivatives of sobetirome
IL253381A0 (en) History of h9-pyrrolo-dipyridine
IL271607A (en) New azaquinoline histories
IL263050B (en) History of Subtirum
HK1245258A1 (zh) 新的二氟酮酰胺衍生物
HK1252275A1 (zh) 羥烷基噻二唑衍生物
HUE050450T2 (hu) Fluoralkil-fluorén-származékok
IL248773A0 (en) History of naphthyridinedione
IL248629A0 (en) Substances containing diheteroaryl conjugated to cycloalkyl and their uses
IL251005B (en) Pyrido-oxazinone derivatives
HK1254202A1 (zh) 三唑衍生物
HUE057600T2 (hu) Szubsztituált xantin-származékok
PL3119744T3 (pl) Pochodne 2-cyjano-3-cyklopropylo-3-hydroksy-N-arylo-tioakryloamidu
IL271290A (en) Dihydro-pyrrolo-pyridine derivatives
GB201416351D0 (en) Heterocyclic derivatives
PT3319956T (pt) Derivados de oxopiridina substituída