PT3365345T - Composto de oxa- azaespiro tendo atividade contra a dor - Google Patents
Composto de oxa- azaespiro tendo atividade contra a dorInfo
- Publication number
- PT3365345T PT3365345T PT167847946T PT16784794T PT3365345T PT 3365345 T PT3365345 T PT 3365345T PT 167847946 T PT167847946 T PT 167847946T PT 16784794 T PT16784794 T PT 16784794T PT 3365345 T PT3365345 T PT 3365345T
- Authority
- PT
- Portugal
- Prior art keywords
- oxa
- activity against
- against pain
- azaspiro compounds
- azaspiro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15382522 | 2015-10-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3365345T true PT3365345T (pt) | 2020-05-27 |
Family
ID=54364220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT167847946T PT3365345T (pt) | 2015-10-23 | 2016-10-21 | Composto de oxa- azaespiro tendo atividade contra a dor |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10183918B2 (pt) |
| EP (1) | EP3365345B1 (pt) |
| JP (1) | JP6891386B2 (pt) |
| CN (1) | CN108137617B (pt) |
| AR (1) | AR106444A1 (pt) |
| CA (1) | CA2999924A1 (pt) |
| ES (1) | ES2794801T3 (pt) |
| MX (1) | MX2018004776A (pt) |
| PT (1) | PT3365345T (pt) |
| TW (1) | TW201808921A (pt) |
| WO (1) | WO2017067663A1 (pt) |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9603137D0 (en) * | 1996-02-15 | 1996-04-17 | Merck Sharp & Dohme | Therapeutic agents |
| US6114541A (en) | 1997-03-10 | 2000-09-05 | Hoffmann-La Roche Inc. | Method for the preparation of α-Bromo-Lactam derivatives |
| EP1634873A1 (en) | 2004-08-27 | 2006-03-15 | Laboratorios Del Dr. Esteve, S.A. | Sigma receptor inhibitors |
| EP1829869A1 (en) | 2006-03-02 | 2007-09-05 | Laboratorios Del Dr. Esteve, S.A. | 4,5,6,7-Tetrahydrobenzo[b]thiophene derivatives and their use as sigma receptor ligands |
| EP1847542A1 (en) | 2006-04-21 | 2007-10-24 | Laboratorios del Dr. Esteve S.A. | Spiro[benzopyran] or spiro[benzofuran] derivatives which inhibit the sigma receptor |
| GB0700786D0 (en) * | 2007-01-15 | 2007-02-21 | Pfizer Ltd | Morpholine dopamine agonists for the treatment of pain |
| EP2070933A1 (en) | 2007-12-07 | 2009-06-17 | Laboratorios del Dr. Esteve S.A. | Tricyclic triazolic compounds |
| AU2012229187B2 (en) * | 2011-03-14 | 2016-11-10 | Vertex Pharmaceuticals Incorporated | Morpholine-spirocyclic piperidine amides as modulators of ion channels |
| TW201615643A (zh) * | 2014-06-02 | 2016-05-01 | 伊史帝夫博士實驗室股份有限公司 | 具有多重模式抗疼痛活性之１－氧雜－４，９－二氮雜螺十一烷化合物之烷基與芳基衍生物 |
| TW201615642A (zh) * | 2014-06-02 | 2016-05-01 | 伊史帝夫博士實驗室股份有限公司 | 具有多重模式抗疼痛活性的１－氧雜－４，９－二氮雜螺十一烷化合物之醯胺衍生物 |
| TWI685497B (zh) * | 2014-06-02 | 2020-02-21 | 西班牙商伊史帝夫製藥公司 | 具有多重模式抗疼痛活性的１-氧雜-４,９-二氮雜螺十一烷化合物之烷基衍生物 |
-
2016
- 2016-10-21 MX MX2018004776A patent/MX2018004776A/es unknown
- 2016-10-21 EP EP16784794.6A patent/EP3365345B1/en active Active
- 2016-10-21 JP JP2018520109A patent/JP6891386B2/ja active Active
- 2016-10-21 US US15/769,502 patent/US10183918B2/en active Active
- 2016-10-21 AR ARP160103224A patent/AR106444A1/es unknown
- 2016-10-21 CN CN201680061705.1A patent/CN108137617B/zh active Active
- 2016-10-21 ES ES16784794T patent/ES2794801T3/es active Active
- 2016-10-21 TW TW105134201A patent/TW201808921A/zh unknown
- 2016-10-21 CA CA2999924A patent/CA2999924A1/en not_active Abandoned
- 2016-10-21 PT PT167847946T patent/PT3365345T/pt unknown
- 2016-10-21 WO PCT/EP2016/001741 patent/WO2017067663A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| TW201808921A (zh) | 2018-03-16 |
| EP3365345A1 (en) | 2018-08-29 |
| CN108137617A (zh) | 2018-06-08 |
| WO2017067663A1 (en) | 2017-04-27 |
| US10183918B2 (en) | 2019-01-22 |
| CN108137617B (zh) | 2021-07-02 |
| MX2018004776A (es) | 2018-06-19 |
| ES2794801T3 (es) | 2020-11-19 |
| JP2018531267A (ja) | 2018-10-25 |
| US20180312479A1 (en) | 2018-11-01 |
| EP3365345B1 (en) | 2020-02-26 |
| AR106444A1 (es) | 2018-01-17 |
| JP6891386B2 (ja) | 2021-06-18 |
| CA2999924A1 (en) | 2017-04-27 |
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