PT3305768T - Sal de sódio de um inibidor do transportador do ácido úrico e forma cristalina do mesmo - Google Patents
Sal de sódio de um inibidor do transportador do ácido úrico e forma cristalina do mesmoInfo
- Publication number
- PT3305768T PT3305768T PT167993310T PT16799331T PT3305768T PT 3305768 T PT3305768 T PT 3305768T PT 167993310 T PT167993310 T PT 167993310T PT 16799331 T PT16799331 T PT 16799331T PT 3305768 T PT3305768 T PT 3305768T
- Authority
- PT
- Portugal
- Prior art keywords
- sodium salt
- crystalline form
- uric acid
- acid transporter
- transporter inhibitor
- Prior art date
Links
- 108010078791 Carrier Proteins Proteins 0.000 title 1
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 title 1
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 159000000000 sodium salts Chemical class 0.000 title 1
- 229940116269 uric acid Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510280720 | 2015-05-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3305768T true PT3305768T (pt) | 2020-08-03 |
Family
ID=57393793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT167993310T PT3305768T (pt) | 2015-05-27 | 2016-05-26 | Sal de sódio de um inibidor do transportador do ácido úrico e forma cristalina do mesmo |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US10196361B2 (pt) |
| EP (1) | EP3305768B1 (pt) |
| JP (1) | JP6738350B2 (pt) |
| KR (1) | KR20180006441A (pt) |
| CN (1) | CN107001276B (pt) |
| AU (1) | AU2016269359B2 (pt) |
| BR (1) | BR112017022505A2 (pt) |
| CA (1) | CA2984961C (pt) |
| CY (1) | CY1123262T1 (pt) |
| DK (1) | DK3305768T3 (pt) |
| ES (1) | ES2811325T3 (pt) |
| HR (1) | HRP20201178T1 (pt) |
| HU (1) | HUE051640T2 (pt) |
| LT (1) | LT3305768T (pt) |
| MX (1) | MX379184B (pt) |
| PL (1) | PL3305768T3 (pt) |
| PT (1) | PT3305768T (pt) |
| RS (1) | RS60749B1 (pt) |
| RU (1) | RU2719484C2 (pt) |
| SI (1) | SI3305768T1 (pt) |
| SM (1) | SMT202000421T1 (pt) |
| WO (1) | WO2016188444A1 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX379184B (es) * | 2015-05-27 | 2025-03-10 | Jiangsu Hengrui Medicine Co | Sal sodica de inhibidor de transportador de acido urico y su forma cristalina. |
| CN108201529B (zh) * | 2016-12-16 | 2021-10-08 | 江苏恒瑞医药股份有限公司 | 一种含有尿酸转运蛋白抑制剂的药物组合物及其制备方法 |
| CN110467571B (zh) * | 2018-05-11 | 2021-02-26 | 江苏恒瑞医药股份有限公司 | 一种制备环烷基甲酸类衍生物或其可药用盐的方法 |
| WO2025072489A2 (en) | 2023-09-27 | 2025-04-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Analogues of n-lactoyl-phenylalanine, methods of synthesis, and methods of use |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SA04250253B1 (ar) * | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| AR051780A1 (es) * | 2004-11-29 | 2007-02-07 | Japan Tobacco Inc | Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos |
| NO2998296T3 (pt) * | 2013-05-13 | 2018-08-11 | ||
| MX379184B (es) * | 2015-05-27 | 2025-03-10 | Jiangsu Hengrui Medicine Co | Sal sodica de inhibidor de transportador de acido urico y su forma cristalina. |
-
2016
- 2016-05-26 MX MX2017014319A patent/MX379184B/es unknown
- 2016-05-26 SM SM20200421T patent/SMT202000421T1/it unknown
- 2016-05-26 LT LTEP16799331.0T patent/LT3305768T/lt unknown
- 2016-05-26 PL PL16799331T patent/PL3305768T3/pl unknown
- 2016-05-26 RU RU2017142996A patent/RU2719484C2/ru active
- 2016-05-26 PT PT167993310T patent/PT3305768T/pt unknown
- 2016-05-26 SI SI201630871T patent/SI3305768T1/sl unknown
- 2016-05-26 HR HRP20201178TT patent/HRP20201178T1/hr unknown
- 2016-05-26 HU HUE16799331A patent/HUE051640T2/hu unknown
- 2016-05-26 ES ES16799331T patent/ES2811325T3/es active Active
- 2016-05-26 BR BR112017022505-0A patent/BR112017022505A2/pt not_active Application Discontinuation
- 2016-05-26 RS RS20200924A patent/RS60749B1/sr unknown
- 2016-05-26 DK DK16799331.0T patent/DK3305768T3/da active
- 2016-05-26 EP EP16799331.0A patent/EP3305768B1/en active Active
- 2016-05-26 US US15/574,328 patent/US10196361B2/en active Active
- 2016-05-26 KR KR1020177035949A patent/KR20180006441A/ko not_active Ceased
- 2016-05-26 AU AU2016269359A patent/AU2016269359B2/en not_active Ceased
- 2016-05-26 CA CA2984961A patent/CA2984961C/en active Active
- 2016-05-26 JP JP2017555478A patent/JP6738350B2/ja not_active Expired - Fee Related
- 2016-05-26 WO PCT/CN2016/083423 patent/WO2016188444A1/zh not_active Ceased
- 2016-05-26 CN CN201680003846.8A patent/CN107001276B/zh active Active
-
2018
- 2018-10-11 US US16/157,696 patent/US10358424B2/en active Active
-
2020
- 2020-08-04 CY CY20201100720T patent/CY1123262T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112017022505A2 (pt) | 2018-07-17 |
| AU2016269359A1 (en) | 2017-11-23 |
| WO2016188444A1 (zh) | 2016-12-01 |
| SMT202000421T1 (it) | 2020-09-10 |
| US20180134663A1 (en) | 2018-05-17 |
| CA2984961A1 (en) | 2016-12-01 |
| KR20180006441A (ko) | 2018-01-17 |
| DK3305768T3 (da) | 2020-08-10 |
| US20190040015A1 (en) | 2019-02-07 |
| CN107001276B (zh) | 2020-03-13 |
| CN107001276A (zh) | 2017-08-01 |
| RU2017142996A3 (pt) | 2019-11-20 |
| RS60749B1 (sr) | 2020-10-30 |
| JP2018515454A (ja) | 2018-06-14 |
| EP3305768A4 (en) | 2019-02-13 |
| AU2016269359B2 (en) | 2020-02-06 |
| EP3305768A1 (en) | 2018-04-11 |
| LT3305768T (lt) | 2020-08-25 |
| HRP20201178T1 (hr) | 2020-11-13 |
| RU2017142996A (ru) | 2019-06-27 |
| CA2984961C (en) | 2023-08-01 |
| ES2811325T3 (es) | 2021-03-11 |
| RU2719484C2 (ru) | 2020-04-17 |
| JP6738350B2 (ja) | 2020-08-12 |
| EP3305768B1 (en) | 2020-07-01 |
| HUE051640T2 (hu) | 2021-03-01 |
| SI3305768T1 (sl) | 2020-10-30 |
| US10358424B2 (en) | 2019-07-23 |
| PL3305768T3 (pl) | 2020-12-28 |
| US10196361B2 (en) | 2019-02-05 |
| MX379184B (es) | 2025-03-10 |
| MX2017014319A (es) | 2018-03-07 |
| CY1123262T1 (el) | 2021-12-31 |
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