PT3148961T - Método para preparar um sal do ácido acetilsalicílico e um aminoácido básico - Google Patents

Método para preparar um sal do ácido acetilsalicílico e um aminoácido básico

Info

Publication number
PT3148961T
PT3148961T PT15724710T PT15724710T PT3148961T PT 3148961 T PT3148961 T PT 3148961T PT 15724710 T PT15724710 T PT 15724710T PT 15724710 T PT15724710 T PT 15724710T PT 3148961 T PT3148961 T PT 3148961T
Authority
PT
Portugal
Prior art keywords
salt
preparing
basic amino
amino acid
acid
Prior art date
Application number
PT15724710T
Other languages
English (en)
Inventor
Arnal Thierry
Original Assignee
Unither Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unither Pharmaceuticals filed Critical Unither Pharmaceuticals
Publication of PT3148961T publication Critical patent/PT3148961T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38—Separation; Purification; Stabilisation; Use of additives
    • C07C227/40—Separation; Purification
    • C07C227/42—Crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C07C67/52—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/12—Acetic acid esters
    • C07C69/14—Acetic acid esters of monohydroxylic compounds
    • C07C69/145—Acetic acid esters of monohydroxylic compounds of unsaturated alcohols
    • C07C69/157—Acetic acid esters of monohydroxylic compounds of unsaturated alcohols containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT15724710T 2014-05-28 2015-05-28 Método para preparar um sal do ácido acetilsalicílico e um aminoácido básico PT3148961T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1454830A FR3021654B1 (fr) 2014-05-28 2014-05-28 Procede de preparation d'un sel d'acide acetylsalicylique et d'un acide amine basique

Publications (1)

Publication Number Publication Date
PT3148961T true PT3148961T (pt) 2018-11-05

Family

ID=51570555

Family Applications (1)

Application Number Title Priority Date Filing Date
PT15724710T PT3148961T (pt) 2014-05-28 2015-05-28 Método para preparar um sal do ácido acetilsalicílico e um aminoácido básico

Country Status (6)

Country Link
US (1) US9745246B2 (pt)
EP (1) EP3148961B1 (pt)
ES (1) ES2690066T3 (pt)
FR (1) FR3021654B1 (pt)
PT (1) PT3148961T (pt)
WO (1) WO2015181304A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106674036B (zh) * 2016-12-22 2018-08-14 河南中医学院 非有机溶剂法合成赖氨匹林的方法
DK3558920T3 (da) 2016-12-23 2021-07-05 Aspiair Gmbh Forbedret syntese af lysinacetylsalicylat-glycin-partikler

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10034802A1 (de) * 2000-07-18 2002-01-31 Bayer Ag Stabile Salze von O-Acetylsalicylsäure mit basischen Aminosäuren
FR2950625B1 (fr) * 2009-09-30 2016-12-02 Holis Tech Procede de preparation d'un sel d'acide o-acetylsalicylique d'un acide amine basique et composition obtenue
FR2965261B1 (fr) * 2009-09-30 2012-10-26 Holis Technologies Procede de preparation d'un sel d'acide o-acetylsalicylique d'un acide amine basique et composition obtenue par ce procede
FR2973370B1 (fr) * 2011-03-29 2013-05-03 Holis Technologies Procede a faible cout pour la preparation d'un acide o-acetylsalicyclique et d'un acide amine basique
CN102503845A (zh) * 2011-09-28 2012-06-20 广州普星药业有限公司 一种dl-赖氨酸阿司匹林盐的制备方法及其应用
ITMI20121144A1 (it) * 2012-06-28 2013-12-29 Dipharma Francis Srl Procedimento per la preparazione di un sale di un farmaco antinfiammatorio non steroideo

Also Published As

Publication number Publication date
EP3148961B1 (fr) 2018-08-22
US9745246B2 (en) 2017-08-29
US20170081270A1 (en) 2017-03-23
WO2015181304A1 (fr) 2015-12-03
FR3021654A1 (fr) 2015-12-04
EP3148961A1 (fr) 2017-04-05
FR3021654B1 (fr) 2016-06-24
ES2690066T3 (es) 2018-11-19

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