PT3215158T - Apilimod para utilização no tratamento de cancro renal - Google Patents

Apilimod para utilização no tratamento de cancro renal

Info

Publication number
PT3215158T
PT3215158T PT15795318T PT15795318T PT3215158T PT 3215158 T PT3215158 T PT 3215158T PT 15795318 T PT15795318 T PT 15795318T PT 15795318 T PT15795318 T PT 15795318T PT 3215158 T PT3215158 T PT 3215158T
Authority
PT
Portugal
Prior art keywords
apilimod
treatment
renal cancer
renal
cancer
Prior art date
Application number
PT15795318T
Other languages
English (en)
Portuguese (pt)
Inventor
BEEHARRY Neil
Gayle Sophia
LANDRETTE Sean
Beckett Paul
Conrad Chris
Xu Tian
M Rothberg Jonathan
Lichenstein Henri
Original Assignee
Ai Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ai Therapeutics Inc filed Critical Ai Therapeutics Inc
Publication of PT3215158T publication Critical patent/PT3215158T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
PT15795318T 2014-11-07 2015-11-06 Apilimod para utilização no tratamento de cancro renal PT3215158T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462077127P 2014-11-07 2014-11-07

Publications (1)

Publication Number Publication Date
PT3215158T true PT3215158T (pt) 2019-08-23

Family

ID=54548302

Family Applications (1)

Application Number Title Priority Date Filing Date
PT15795318T PT3215158T (pt) 2014-11-07 2015-11-06 Apilimod para utilização no tratamento de cancro renal

Country Status (16)

Country Link
US (3) US10206910B2 (cg-RX-API-DMAC7.html)
EP (2) EP3215158B1 (cg-RX-API-DMAC7.html)
JP (1) JP6705828B2 (cg-RX-API-DMAC7.html)
KR (1) KR20170098812A (cg-RX-API-DMAC7.html)
CN (1) CN107249638B (cg-RX-API-DMAC7.html)
AU (1) AU2015342869A1 (cg-RX-API-DMAC7.html)
BR (1) BR112017008799A2 (cg-RX-API-DMAC7.html)
CA (1) CA2966359A1 (cg-RX-API-DMAC7.html)
ES (1) ES2741399T3 (cg-RX-API-DMAC7.html)
HU (1) HUE044557T2 (cg-RX-API-DMAC7.html)
IL (1) IL251905B (cg-RX-API-DMAC7.html)
MX (1) MX377593B (cg-RX-API-DMAC7.html)
PL (1) PL3215158T3 (cg-RX-API-DMAC7.html)
PT (1) PT3215158T (cg-RX-API-DMAC7.html)
RU (1) RU2727802C2 (cg-RX-API-DMAC7.html)
WO (1) WO2016073877A1 (cg-RX-API-DMAC7.html)

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EP3215158B1 (en) 2014-11-07 2019-05-08 AI Therapeutics, Inc. Apilimod for use in the treatment of renal cancer
CN107427522B (zh) * 2014-11-07 2021-06-15 人工智能治疗公司 用于治疗黑素瘤的阿吡莫德
US20190015421A1 (en) * 2016-01-21 2019-01-17 Lam Therapeutics, Inc. Biomarkers for Treating Cancer with Apilimod
CN109952113A (zh) * 2016-08-25 2019-06-28 人工智能治疗公司 包含pikfyve抑制剂的组合物和与rank信号传导的抑制相关的方法
CN110167559A (zh) * 2016-10-12 2019-08-23 人工智能治疗公司 阿匹莫德组合物和将其用于治疗阿尔茨海默病中的方法
US11066410B2 (en) 2017-03-24 2021-07-20 3100 Central Expressway Llc Fused triazolo-pyrimidine compounds having useful pharmaceutical application
EA202091786A1 (ru) 2018-01-26 2020-10-20 Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния Способы и композиции для лечения ангиогенных расстройств с применением агентов против фрэс
WO2019164861A1 (en) 2018-02-21 2019-08-29 AI Therapeutics, Inc. Combination therapy with apilimod and glutamatergic agents
MX2022006241A (es) 2019-11-25 2022-08-22 Univ California Inhibidores de vegf de accion prolongada para la neovascularizacion intraocular.
EP4090426B1 (en) 2020-01-13 2025-12-31 Verge Analytics, Inc. Substitutes for pyrazolos and pyrimidines and their uses
CN114306370A (zh) * 2021-12-31 2022-04-12 北京悦康科创医药科技股份有限公司 反义寡核苷酸在制备治疗肾癌药物中的应用

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EP3215158B1 (en) 2014-11-07 2019-05-08 AI Therapeutics, Inc. Apilimod for use in the treatment of renal cancer
CN107427522B (zh) 2014-11-07 2021-06-15 人工智能治疗公司 用于治疗黑素瘤的阿吡莫德
KR101761573B1 (ko) 2014-12-29 2017-07-26 주식회사 인트론바이오테크놀로지 신규한 장출혈성 대장균 박테리오파지 Ｅｓｃ-ＣＨＰ-1 및 이의 장출혈성 대장균 증식 억제 용도
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Also Published As

Publication number Publication date
AU2015342869A1 (en) 2017-06-15
JP6705828B2 (ja) 2020-06-03
HUE044557T2 (hu) 2019-11-28
ES2741399T3 (es) 2020-02-10
EP3215158A1 (en) 2017-09-13
RU2017119065A (ru) 2018-12-07
RU2727802C2 (ru) 2020-07-24
JP2017535601A (ja) 2017-11-30
IL251905A0 (en) 2017-06-29
CN107249638B (zh) 2021-05-14
RU2017119065A3 (cg-RX-API-DMAC7.html) 2019-06-05
EP3581184A1 (en) 2019-12-18
EP3581184B1 (en) 2021-02-24
BR112017008799A2 (pt) 2017-12-19
US11166944B2 (en) 2021-11-09
US20190201385A1 (en) 2019-07-04
IL251905B (en) 2021-03-25
US20200297706A1 (en) 2020-09-24
EP3215158B1 (en) 2019-05-08
WO2016073877A1 (en) 2016-05-12
PL3215158T3 (pl) 2019-11-29
MX2017006015A (es) 2017-11-17
US10206910B2 (en) 2019-02-19
CN107249638A (zh) 2017-10-13
MX377593B (es) 2025-03-10
KR20170098812A (ko) 2017-08-30
US20170333408A1 (en) 2017-11-23
CA2966359A1 (en) 2016-05-12

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