PT3116498T - Formulação para análogos anticolinérgicos suaves - Google Patents

Formulação para análogos anticolinérgicos suaves

Info

Publication number
PT3116498T
PT3116498T PT15762178T PT15762178T PT3116498T PT 3116498 T PT3116498 T PT 3116498T PT 15762178 T PT15762178 T PT 15762178T PT 15762178 T PT15762178 T PT 15762178T PT 3116498 T PT3116498 T PT 3116498T
Authority
PT
Portugal
Prior art keywords
anticolinergical
analogs
formulation
soft
soft anticolinergical
Prior art date
Application number
PT15762178T
Other languages
English (en)
Portuguese (pt)
Inventor
S Bodor Nicholas
Angulo David
J Koleng John
Original Assignee
Bodor Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bodor Laboratories Inc filed Critical Bodor Laboratories Inc
Publication of PT3116498T publication Critical patent/PT3116498T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12Oxygen or sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00Anti-perspirants or body deodorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
PT15762178T 2014-03-13 2015-03-12 Formulação para análogos anticolinérgicos suaves PT3116498T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461952505P 2014-03-13 2014-03-13
US14/285,488 US20150259283A1 (en) 2014-03-13 2014-05-22 Formulation for soft anticholinergic analogs

Publications (1)

Publication Number Publication Date
PT3116498T true PT3116498T (pt) 2019-02-11

Family

ID=54068191

Family Applications (2)

Application Number Title Priority Date Filing Date
PT15762178T PT3116498T (pt) 2014-03-13 2015-03-12 Formulação para análogos anticolinérgicos suaves
PT168285534T PT3325487T (pt) 2014-03-13 2016-07-21 Formulação para análogos anticolinérgicos lisos

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT168285534T PT3325487T (pt) 2014-03-13 2016-07-21 Formulação para análogos anticolinérgicos lisos

Country Status (20)

Country Link
US (8) US20150259283A1 (enrdf_load_stackoverflow)
EP (1) EP3116498B1 (enrdf_load_stackoverflow)
JP (5) JP6293919B2 (enrdf_load_stackoverflow)
KR (3) KR20230145522A (enrdf_load_stackoverflow)
CN (3) CN110420167B (enrdf_load_stackoverflow)
AU (2) AU2015229243B2 (enrdf_load_stackoverflow)
BR (1) BR112016021011B1 (enrdf_load_stackoverflow)
CA (1) CA2941649C (enrdf_load_stackoverflow)
DK (2) DK3116498T3 (enrdf_load_stackoverflow)
ES (1) ES2710292T3 (enrdf_load_stackoverflow)
HU (1) HUE041868T2 (enrdf_load_stackoverflow)
IL (1) IL247571B (enrdf_load_stackoverflow)
MX (1) MX369129B (enrdf_load_stackoverflow)
MY (1) MY183531A (enrdf_load_stackoverflow)
PH (1) PH12016501732A1 (enrdf_load_stackoverflow)
PL (1) PL3116498T3 (enrdf_load_stackoverflow)
PT (2) PT3116498T (enrdf_load_stackoverflow)
SG (1) SG11201607480SA (enrdf_load_stackoverflow)
WO (1) WO2015138776A1 (enrdf_load_stackoverflow)
ZA (1) ZA201607071B (enrdf_load_stackoverflow)

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US11807604B1 (en) * 2022-02-16 2023-11-07 Miralogx Llc Pharmaceutical compounds, pharmaceutical compositions, and methods of treating asthma and other disorders
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US20150259283A1 (en) 2014-03-13 2015-09-17 Brickell Biotech, Inc. Formulation for soft anticholinergic analogs
CN119033771A (zh) 2015-07-21 2024-11-29 博多尔实验仪器公司 软性抗胆碱能药类似物的制剂
TWI719046B (zh) 2016-07-21 2021-02-21 美商波德實驗股份有限公司 軟性抗膽鹼類似物之製劑

Also Published As

Publication number Publication date
US20150320722A1 (en) 2015-11-12
HUE041868T2 (hu) 2019-05-28
DK3116498T3 (en) 2019-03-11
US11084788B2 (en) 2021-08-10
KR20160133492A (ko) 2016-11-22
PL3116498T3 (pl) 2019-05-31
US20200113869A1 (en) 2020-04-16
BR112016021011A8 (pt) 2021-07-20
JP2020079321A (ja) 2020-05-28
PT3325487T (pt) 2021-07-29
US20150259283A1 (en) 2015-09-17
WO2015138776A1 (en) 2015-09-17
JP2017507970A (ja) 2017-03-23
CA2941649A1 (en) 2015-09-17
US10961191B2 (en) 2021-03-30
CN110917124A (zh) 2020-03-27
MX369129B (es) 2019-10-30
JP6762047B2 (ja) 2020-09-30
MY183531A (en) 2021-02-25
ES2710292T3 (es) 2019-04-24
DK3325487T3 (da) 2021-08-02
JP6293919B2 (ja) 2018-03-14
EP3116498B1 (en) 2018-12-12
CN110420167A (zh) 2019-11-08
JP2018115203A (ja) 2018-07-26
US20170020845A1 (en) 2017-01-26
AU2015229243A1 (en) 2016-10-20
JP2017214429A (ja) 2017-12-07
BR112016021011B1 (pt) 2022-12-13
SG11201607480SA (en) 2016-10-28
JP2019189650A (ja) 2019-10-31
CN106456603B (zh) 2020-01-10
PH12016501732B1 (en) 2017-02-06
ZA201607071B (en) 2018-12-19
KR20220119517A (ko) 2022-08-29
BR112016021011A2 (pt) 2017-08-15
CN106456603A (zh) 2017-02-22
US11034652B2 (en) 2021-06-15
KR102586868B1 (ko) 2023-10-11
US20210078946A1 (en) 2021-03-18
US20210087142A1 (en) 2021-03-25
JP6756763B2 (ja) 2020-09-16
US12398102B2 (en) 2025-08-26
CN110917124B (zh) 2023-06-20
KR102433868B1 (ko) 2022-08-19
IL247571A0 (en) 2016-11-30
AU2019257421B2 (en) 2021-10-21
PH12016501732A1 (en) 2017-02-06
US20210198195A1 (en) 2021-07-01
EP3116498A4 (en) 2017-11-08
KR20230145522A (ko) 2023-10-17
MX2016011529A (es) 2016-12-07
US10947192B2 (en) 2021-03-16
CA2941649C (en) 2021-03-02
IL247571B (en) 2020-03-31
AU2015229243B2 (en) 2019-11-21
CN110420167B (zh) 2023-02-17
EP3116498A1 (en) 2017-01-18
AU2019257421A1 (en) 2019-11-21
JP6461267B2 (ja) 2019-01-30
US20200093791A1 (en) 2020-03-26

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