PT2991976T - Síntese de 3-(5-amino-2-metil-4-oxoquinazolina-3(4h)il)piperidina-2,6-diona - Google Patents

Síntese de 3-(5-amino-2-metil-4-oxoquinazolina-3(4h)il)piperidina-2,6-diona

Info

Publication number
PT2991976T
PT2991976T PT147283816T PT14728381T PT2991976T PT 2991976 T PT2991976 T PT 2991976T PT 147283816 T PT147283816 T PT 147283816T PT 14728381 T PT14728381 T PT 14728381T PT 2991976 T PT2991976 T PT 2991976T
Authority
PT
Portugal
Prior art keywords
oxoquinazolin
dione
piperidine
synthesis
amino
Prior art date
Application number
PT147283816T
Other languages
English (en)
Inventor
Choudhury Anusuya
Man Hon-Wah
L Ruchelman Alexander
M Cohen Benjamin
M Kreilein Matthew
W Leong William
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of PT2991976T publication Critical patent/PT2991976T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
PT147283816T 2013-05-01 2014-04-30 Síntese de 3-(5-amino-2-metil-4-oxoquinazolina-3(4h)il)piperidina-2,6-diona PT2991976T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361818254P 2013-05-01 2013-05-01

Publications (1)

Publication Number Publication Date
PT2991976T true PT2991976T (pt) 2017-11-14

Family

ID=50885008

Family Applications (1)

Application Number Title Priority Date Filing Date
PT147283816T PT2991976T (pt) 2013-05-01 2014-04-30 Síntese de 3-(5-amino-2-metil-4-oxoquinazolina-3(4h)il)piperidina-2,6-diona

Country Status (25)

Country Link
US (3) US9067912B2 (pt)
EP (2) EP2991976B1 (pt)
JP (2) JP6490055B2 (pt)
KR (1) KR20160003228A (pt)
CN (2) CN107935994A (pt)
AR (1) AR096165A1 (pt)
AU (2) AU2014260011A1 (pt)
CA (1) CA2910971A1 (pt)
CY (1) CY1119525T1 (pt)
DK (1) DK2991976T3 (pt)
ES (1) ES2645944T3 (pt)
HR (1) HRP20171535T1 (pt)
HU (1) HUE034770T2 (pt)
LT (1) LT2991976T (pt)
MX (1) MX363652B (pt)
NZ (1) NZ628322A (pt)
PH (1) PH12015502477A1 (pt)
PL (1) PL2991976T3 (pt)
PT (1) PT2991976T (pt)
RS (1) RS56565B1 (pt)
RU (1) RU2015151359A (pt)
SG (1) SG11201508836XA (pt)
SI (1) SI2991976T1 (pt)
TW (1) TW201536766A (pt)
WO (1) WO2014179416A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2420497T3 (en) 2006-09-26 2016-03-07 Celgene Corp 5-substituted quinazolinone derivatives as anticancer agents
MX2013010360A (es) 2011-03-11 2014-04-14 Celgene Corp Formas solidas sde 3-(5-amino-2-metil-4-oxo-4h-quinazolin-3-il)-pi peridin-2,6-diona, y sus composiciones farmaceuticas y usos.
ES2814952T3 (es) 2012-09-04 2021-03-29 Celgene Corp Isotopólogos de 3-(5-amino-2-metil-4-oxoquinazolin-3(4H)-il) piperidina-2-6-diona y métodos de preparación de los mismos
US10973822B2 (en) 2015-07-02 2021-04-13 Celgene Corporation Combination therapy for treatment of hematological cancers and solid tumors
CN106083622B (zh) * 2016-06-16 2018-06-19 常州齐晖药业有限公司 一种甲苯咪唑中间体3,4-二氨基二苯甲酮的制备方法
WO2018165142A1 (en) * 2017-03-07 2018-09-13 Celgene Corporation Solid forms of 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione, and their pharmaceutical compositions and uses
CN113101295A (zh) * 2020-03-20 2021-07-13 上海疆云医疗健康科技有限公司 二苯乙烯类似物在治疗糖尿病肾脏疾病中的用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101528702A (zh) * 2006-06-08 2009-09-09 阿雷生物药品公司 喹啉化合物和使用方法
DK2420497T3 (en) * 2006-09-26 2016-03-07 Celgene Corp 5-substituted quinazolinone derivatives as anticancer agents
CA2829592A1 (en) * 2011-03-11 2012-09-20 Celgene Corporation Methods of treating cancer using 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione
MX2013010360A (es) * 2011-03-11 2014-04-14 Celgene Corp Formas solidas sde 3-(5-amino-2-metil-4-oxo-4h-quinazolin-3-il)-pi peridin-2,6-diona, y sus composiciones farmaceuticas y usos.
ES2814952T3 (es) 2012-09-04 2021-03-29 Celgene Corp Isotopólogos de 3-(5-amino-2-metil-4-oxoquinazolin-3(4H)-il) piperidina-2-6-diona y métodos de preparación de los mismos
US9540340B2 (en) * 2013-01-14 2017-01-10 Deuterx, Llc 3-(5-substituted-4-oxoquinazolin-3(4H)-yl)-3-deutero-piperidine-2,6-dione derivatives and compositions comprising and methods of using the same

Also Published As

Publication number Publication date
EP3199532A1 (en) 2017-08-02
MX2015015073A (es) 2016-03-03
SI2991976T1 (sl) 2017-11-30
CN105377831A (zh) 2016-03-02
MX363652B (es) 2019-03-28
WO2014179416A1 (en) 2014-11-06
AU2014260011A1 (en) 2015-11-12
SG11201508836XA (en) 2015-11-27
HUE034770T2 (hu) 2018-02-28
RU2015151359A (ru) 2017-06-06
CN105377831B (zh) 2018-02-02
US9303014B2 (en) 2016-04-05
US9266858B2 (en) 2016-02-23
PH12015502477A1 (en) 2016-02-22
PL2991976T3 (pl) 2018-01-31
AR096165A1 (es) 2015-12-09
CA2910971A1 (en) 2014-11-06
NZ628322A (en) 2017-06-30
LT2991976T (lt) 2017-10-25
TW201536766A (zh) 2015-10-01
CN107935994A (zh) 2018-04-20
US20140330016A1 (en) 2014-11-06
JP2016517886A (ja) 2016-06-20
ES2645944T3 (es) 2017-12-11
RS56565B1 (sr) 2018-02-28
CY1119525T1 (el) 2018-03-07
EP2991976B1 (en) 2017-09-20
AU2017200965A1 (en) 2017-03-02
HRP20171535T1 (hr) 2017-11-17
US20160009685A1 (en) 2016-01-14
US20150274694A1 (en) 2015-10-01
JP2019069958A (ja) 2019-05-09
EP2991976A1 (en) 2016-03-09
US9067912B2 (en) 2015-06-30
DK2991976T3 (da) 2017-11-06
JP6490055B2 (ja) 2019-03-27
KR20160003228A (ko) 2016-01-08

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